KEGG   Pan paniscus (bonobo): 100975534
Entry
100975534         CDS       T02283                                 
Symbol
F2
Name
(RefSeq) prothrombin
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04072  Phospholipase D signaling pathway
pps04080  Neuroactive ligand-receptor interaction
pps04610  Complement and coagulation cascades
pps04611  Platelet activation
pps04810  Regulation of actin cytoskeleton
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    100975534 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100975534 (F2)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100975534 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    100975534 (F2)
   04611 Platelet activation
    100975534 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100975534 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100975534 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pps01002]
    100975534 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pps04147]
    100975534 (F2)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100975534 (F2)
Enzymes [BR:pps01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     100975534 (F2)
Peptidases and inhibitors [BR:pps01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100975534 (F2)
Exosome [BR:pps04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   100975534 (F2)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   100975534 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 100975534
NCBI-ProteinID: XP_003815248
Ensembl: ENSPPAG00000041509
UniProt: A0A2R9C6W7
Position
11:46669925..46690391
AA seq 622 aa
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPSEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDPDRAIEGRTATSEYQPFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
NT seq 1869 nt   +upstreamnt  +downstreamnt
atggcgcacgtccgaggcttgcagctgcctggctgcctggccctggctgccctgtgtagc
cttgtgcacagccagcatgtgttcctggctcctcagcaagcgcggtcgctgctccagcgg
gtccggcgagccaacaccttcctggaggaggtgcgcaagggcaacctggagcgagagtgt
gtggaggagacgtgcagctacgaggaggccttcgaggctctggagtcctccacggctacg
gatgtgttctgggccaagtacacagcttgtgagacagcgaggacgcctcgagataagctt
gctgcatgtctggaaggtaactgtgctgagggtctgggtacgaactaccgagggcatgtg
aacatcacccggtcaggcattgagtgccagctatggaggagtcgctacccacataagcct
gaaatcaactccactacccatcccggggccgacctacaggagaatttctgccgcaacccc
gacagcagcaccacgggaccctggtgctacactacagaccccaccgtgaggaggcaggaa
tgcagcatccctgtctgtggccaggatcaagtcactgtagcgatgactccacgctccgaa
ggctccagtgtgaatctgtcacctccatcggagcagtgtgtccctgatcgagggcagcag
taccaggggcgcctggcagtgaccacacatgggctcccctgcctggcctgggccagcgca
caggccaaggccctgagcaagcaccaggacttcaactcagccgtgcagctggtggagaac
ttctgccgcaacccagacggggatgaggagggtgtgtggtgctatgtggccgggaagcct
ggcgactttgggtactgcgacctcaactattgtgaggaggccgtggaggaggagacagga
gatgggctggatgaggacccagacagggccatcgaagggcgtaccgccaccagtgagtac
cagcctttcttcaatccgaggacctttggctcgggagaggcagactgtgggctgcgacct
ctgttcgagaagaagtcgctggaggacaaaaccgaaagagagctcctggaatcctacatc
gacgggcgtattgtggagggctcggacgcagagatcggcatgtcaccttggcaggtgatg
cttttccggaagagtccccaggagctgctgtgtggggccagcctcatcagtgaccgctgg
gtcctcaccgccgcccactgcctcctgtacccgccctgggacaagaacttcaccgagaat
gaccttctggtgcgcattggcaagcactcccgcaccaggtacgagcgaaacattgaaaag
atatccatgttggaaaagatctacatccaccccaggtacaactggcgggagaacctggac
cgggacattgccctgatgaagctgaagaagcctgttgccttcagtgactacattcaccct
gtgtgtctgcccgacagggagacggcagccagcttgctccaggctggatacaaggggcgg
gtgacaggctggggcaacctgaaggagacgtggacagccaacgttggtaaggggcagccc
agtgtcctgcaggtggtgaacctgcccattgtggagcggccggtctgcaaggactccacc
cggatccgcatcactgacaacatgttctgtgctggttacaagcctgatgaagggaaacga
ggggatgcctgtgaaggtgacagtgggggaccctttgtcatgaagagcccctttaacaac
cgctggtatcaaatgggcatcgtctcatggggtgaaggctgtgaccgggatgggaaatat
ggcttctacacacacgtgttccgcctgaagaagtggatacagaaggtcattgatcagttt
ggagagtag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (28)   

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