KEGG   Pan paniscus (bonobo): 100976893
Entry
100976893         CDS       T02283                                 
Symbol
AMBRA1
Name
(RefSeq) activating molecule in BECN1-regulated autophagy protein 1 isoform X9
  KO
K17985  activating molecule in BECN1-regulated autophagy protein 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04137  Mitophagy - animal
pps04140  Autophagy - animal
pps05010  Alzheimer disease
pps05014  Amyotrophic lateral sclerosis
pps05016  Huntington disease
pps05017  Spinocerebellar ataxia
pps05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:pps00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100976893 (AMBRA1)
   04137 Mitophagy - animal
    100976893 (AMBRA1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100976893 (AMBRA1)
   05014 Amyotrophic lateral sclerosis
    100976893 (AMBRA1)
   05016 Huntington disease
    100976893 (AMBRA1)
   05017 Spinocerebellar ataxia
    100976893 (AMBRA1)
   05022 Pathways of neurodegeneration - multiple diseases
    100976893 (AMBRA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pps04131]
    100976893 (AMBRA1)
   03029 Mitochondrial biogenesis [BR:pps03029]
    100976893 (AMBRA1)
Membrane trafficking [BR:pps04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    100976893 (AMBRA1)
Mitochondrial biogenesis [BR:pps03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    100976893 (AMBRA1)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 eIF2A Acyl_CoA_thio
Other DBs
NCBI-GeneID: 100976893
NCBI-ProteinID: XP_003815252
Ensembl: ENSPPAG00000034195
UniProt: A0A2R9AYL3
Position
11:complement(46355026..46556091)
AA seq 1208 aa
MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA
FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV
RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM
ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL
HNFLHMLSSRSSGIQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGP
TRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSV
LRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEY
DRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRA
CHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSS
RLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLR
RRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQ
NRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFL
LPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKF
DLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHN
LGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETS
MRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWD
QLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQ
LQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQST
TMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRT
ASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCDLTNNNHLLDGGSSRGDAAG
PRGEPRNR
NT seq 3627 nt   +upstreamnt  +downstreamnt
atgaaggttgtcccagaaaagaatgctgtccggatactctgggggcgagaacggggtgct
cgggccatgggagctcagcggcttctgcaggagctggtagaagataaaacccggtggatg
aaatgggagggcaagagagtagaactgccggatagtccacgctctaccttcttattggcc
ttcagcccagacaggactctcttagcctccacccatgtgaaccataatatctatattacg
gaggtgaagactggcaagtgtgttcattccctgattggacaccgccgtactccatggtgt
gtcacttttcatcccaccatctcaggccttattgcttctggctgcctagatggggaggtt
aggatttgggatttacacggtggcagtgaaagctggttcacagatagcaacaatgccatt
gcctccctggctttccaccctacggctcagctcctgctgattgccactgccaatgagatc
cacttctgggactggagtcgacgggaaccctttgctgtggtgaagacagctagtgagatg
gaacgggtccgtctggtgagatttgatccacttggacactacttactcacagcaattgtt
aacccctctaatcaacagggtgatgacgaaccagagatccccatagatggaacagaatta
tcccactaccgtcagcgtgccctcctgcaatcacagccagttcgccggacacctctcctc
cacaatttcctgcacatgctgtcctcccgctcttctggcatccagaccgagcccttccat
cccccggagcaggcctcgtcaacgcagcaagaccagggcctcctgaaccggccgtctgcc
ttcagtacagtccagagcagcactgccggcaacacgctccgcaacctcagtctgggtcct
acccgccgctctttgggagggcctctgtctagccacccttctagatatcaccgagaaata
gctcctgggttgacaggatctgagtggacccggacagtactcagtctgaactcccgctct
gaggcggaatccatgcccccgcccagaaccagtgcctcttcggtgagtttgctgtctgtg
ctgagacagcaggaaggtggctctcaggcatctgtgtacacttcagccacagaagggagg
ggttttccagcatcagggttggcaactgagtcagatggagggaatggctccagccaaaac
aactcaggcagcattcgccatgagcttcagtgtgacctgagacgcttctttctggagtat
gaccggcttcaggagctggatcagagcctgagtggggaagctccccagacccaacaggcc
caggaaatgctcaacaataacattgaatctgagaggccaggcccttcccaccagcccacc
ccacacagcagtgagaacaactccaacctgtcccgtggccacctgaatcgctgtcgtgct
tgccacaatctcctgaccttcaacaacgataccctgcgctgggaaagaaccacacctaac
tattcctctggcgaggctagctcatcttggcaggtccccagctcctttgagagtgtgcca
tcaagtggcagccagttgccacctctcgagcggactgagggccaaacgcccagctccagc
aggctggagttgagcagctctgctagtccgcaggaggagaggactgtgggggtggccttt
aaccaggagacaggccactgggaaagaatttacacccagtccagcagatctggaactgtg
tcacaggaggccttacatcaggatatgcctgaggagagctctgaggaggattcactcagg
aggaggctgctggaatcttccctcatttcattatcccgttatgatggagcaggatccaga
gagcacccaatttacccagacccagcgagattatctcctgctgcatactacgcccagagg
atgatccagtatctctcacggagagacagtattcgccagcgctccatgcgctaccaacag
aaccgtctccgttcttccacctcctcctcttcctcagacaaccagggtccatcagtagag
ggaaccgacttggaatttgaggactttgaggacaatggtgacagatccaggcaccgagct
ccacgcaatgcccggatgtctgcaccttcgcttggacgctttgtcccaaggcgtttcttg
ctgcctgagtacttgccttatgctgggatttttcatgaacgtggacagcctggcttggct
actcactcttctgttaacagggtcctggcaggggcagtgatcggtgatggacagtctgct
gtggccagtaacattgccaatactacctaccggctccagtggtgggacttcactaagttt
gacctccctgaaatcagtaatgcttccgtgaatgtgctggtgcagaactgcaagatctac
aatgatgccagctgtgacatttctgcagatggccagctcctggcagctttcatccccagc
agccagaggggctttcccgatgaaggcatcctggcagtgtactccctggccccccataac
ctgggcgaaatgctctacaccaagcgatttggtcccaatgccatttcggtgagcctgtcc
ccaatgggcagatatgtaatggtgggcttggcctcacgaaggatcctgctgcacccctcc
acagagcacatggtggcccaggtcttcaggctgcaacaggcccatggtggagagacctcc
atgaggagagttttcaacgtcctttatcccatgcctgctgaccagcggagacatgtcagt
atcaactctgcccgttggctgcctgagccagggcttggcttggcctatggtactaacaaa
ggagacctggtgatctgccgaccagaggccttaaactctggtgttgagtactactgggac
cagctgaacgagacggtcttcactgtccattccaacagcaggagcagcgagcggcctgga
accagcagagccacatggaggacagacagagacatggggctgatgaatgccattgggctt
cagccccggaaccctgccacctcagtgacatctcagggcacccagactctggcccttcag
ctgcagaatgccgaaacacagactgagagggaggtgccggagccagggacagccgcctca
ggtcctggtgaaggtgagggttcagagtatggtgccagtggagaagatgcgctcagcagg
atccagaggctgatggcggagggcggcatgacagccgtggtgcagcgggagcagagcacc
accatggcctccatgggcggcttcggcaacaacatcatcgtcagccaccgcattcaccgc
agctctcagacgggcactgaacctggtgctgcccacacctcctcaccccagccctccacc
tctcggggactgctcccagaggccgggcaactggcagagcgaggcctaagcccccggaca
gcttcctgggaccagcctggtacccctgggcgggagccaacccagccaaccctgccctct
tcctcccctgtccccattcctgtttcccttcccagcgctgagggaccaaccctccactgc
gacttgaccaataacaaccaccttctggatggtggcagcagcaggggggacgctgcaggc
cctaggggagaaccacggaacaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   RefSeq(pep) (16)   
DNA sequence (16)   
   RefSeq(nuc) (16)   
Protein domain (4)   
   Pfam (4)   
All databases (53)   

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