KEGG   Pan paniscus (bonobo): 100981353
Entry
100981353         CDS       T02283                                 
Symbol
KDM6A
Name
(RefSeq) lysine-specific demethylase 6A isoform X7
  KO
K11447  lysine-specific demethylase 6A [EC:1.14.11.68]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100981353 (KDM6A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pps03036]
    100981353 (KDM6A)
Enzymes [BR:pps01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     100981353 (KDM6A)
Chromosome and associated proteins [BR:pps03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    MLL3/MLL4 complex
     100981353 (KDM6A)
   Histone demethylases
    100981353 (KDM6A)
SSDB
Motif
Pfam: KDM6_C-hel JmjC TPR_1 KDM6_GATAL TPR_2 TPR_8 TPR_17 TPR_16 TPR_12 TPR_19 TPR_7 TPR_9 TPR_11 TPR_15 ANAPC3
Other DBs
NCBI-GeneID: 100981353
NCBI-ProteinID: XP_003808411
Ensembl: ENSPPAG00000030210
UniProt: A0A2R9ADT5
Position
X:37313000..37548630
AA seq 1356 aa
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPN
GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
ILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNN
LNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLT
ACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQT
LREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKT
SGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
NT seq 4071 nt   +upstreamnt  +downstreamnt
atgaaatcctgcggagtgtcgctcgctaccgccgccgctgccgccgccgctttcggtgat
gaggaaaagaaaatggcggcgggaaaagcgagcggcgagagcgaggaggcgtcccccagc
ctgacagccgaggagagggaggcgctcggcggactggacagccgcctctttgggttcgtg
aggtttcatgaagatggcgccaggacgaaggccctactgggcaaggctgttcgctgctat
gaatctctaatcttaaaagctgaaggaaaagtggagtctgatttcttttgtcaattaggt
cacttcaacctcttattggaagattatccaaaagcattatctgcataccagaggtactac
agtttacagtctgactactggaagaatgctgcctttttatatggtcttggtttggtctac
ttccattataatgcatttcagtgggcaattaaagcatttcaggaggtgctttatgttgat
cccagcttttgtcgagccaaggaaattcatttacgacttgggcttatgttcaaagtgaac
acagactatgagtctagtttaaagcattttcagttagctttggttgactgtaatccctgc
actttgtccaatgctgaaattcagtttcacattgcccacttatatgaaacccagaggaaa
tatcattctgcaaaagaagcttatgaacaacttttgcagacagagaatctttctgcacaa
gtaaaagcaactgtcttacaacagttaggttggatgcatcacactgtagatctcctggga
gataaagccaccaaggaaagctatgctattcagtatctccaaaagtccttggaagcagat
cctaattctggccagtcctggtatttcctcggaaggtgctattcaagtattgggaaagtt
caggatgcctttatatcttacaggcagtctattgataaatcagaagcaagtgcagataca
tggtgttcaataggtgtgctatatcagcagcaaaatcagcccatggatgctttacaggcc
tatatttgtgctgtacaattggaccatggccatgctgcagcctggatggacctaggcact
ctctatgaatcctgcaaccagcctcaggatgccattaaatgctacttaaatgcaactaga
agcaaaagttgtagtaatacctctgcacttgcagcacgaattaagtatttacagaatact
tctgacaattggagtggtggacatgctgtgtcacatcctccagtacagcaacaagctcat
tcatggtgtttgacaccacagaaattacagcatttggaacagctccgcgcaaatagaaat
aatttaaatccagcacagaaactgatgctggaacagctggaaagtcagtttgtcttaatg
caacaacaccaaatgagaccaacaggagttgcacaggtacgatctactggaattcctaat
gggccaacagctgactcatcactgcctacaaactcagtctctggccagcagccacagctt
gctctgaccagagtgcctagcgtctctcagcctggagtccgtcctgcctgccctgggcag
cctttggccaatggacccttttctgcaggccatgttccctgtagcacatcaagaacgctg
ggaagtacagacactattttgataggcaataatcatataacaggaagtggaagtaatgga
aacgtgccttacctgcagcgaaacgcactcactctacctcataaccgcacaaacctgacc
agcagcgcagaggagccgtggaaaaaccaactatctaactccactcaggggcttcacaaa
ggtcagagttcacattcggcaggtcctaatggtgaacgacctctctcttccactgggcct
tcccagcatctccaggcagctggctctggtattcagaatcagaacggacatcccaccctg
cctagcaattcagtaacacagggggctgctctcaatcacctctcctctcacactgctacc
tcaggtggacaacaaggcattaccttaaccaaagagagcaagccttcaggaaacatattg
acggtgcctgaaacaagcaggcacactggagagacacctaacagcactgccagtgtcgag
ggacttcctaatcatgtccatcagatgacagcagatgctgtttgcagtcctagccatgga
gattctaagtcaccaggtttactaagttcagacaatcctcagctctctgccttgttgatg
ggaaaagccaataacaatgtgggtactggaacctgtgacaaagtcaataacatccaccca
gctgttcatacaaagactgataactctgttgcctcttcaccatcttcagccatttccaca
gcaacaccttctccaaaatccactgagcagacaaccacaaacagtgttaccagccttaac
agccctcacagtgggctacacacaattaatggagaagggatggaagaatctcagagcccc
atgaaaacagatctgcttctggttaaccacaaacctagtccacagatcataccatcaatg
tctgtgtccatataccccagctcagcagaagttctgaaggcatgcaggaatctaggtaaa
aatggcttatctaacagtagcattttgttggataaatgtccacctccaagaccaccatct
tcaccataccctcccttgccaaaggacaagttgaatccacctacacctagtatttacttg
gaaaataaacgtgatgctttctttcctccattacatcaattttgtacaaatccgaacaac
cctgttacagtaatacgtggccttgctggagctcttaagttagacctgggacttttctct
actaaaactttggtggaagctaacaatgaacatatggtagaagtgaggacacagttgttg
cagccagcagatgaaaactgggatcccactggaacaaagaaaatctggcattgtgaaagt
aatagatctcatactacaattgctaaatatgcacagtaccaggcctcctcattccaggaa
tcattgagagaagaaaatgaaaaaagaagtcatcataaagaccactcagatagtgaatct
acatcatcagataattctgggaggaggaggaaaggaccctttaaaaccataaagtttggg
accaatattgacctatctgatgacaaaaagtggaagttgcagctacatgagctgactaaa
cttcctgcttttgtgcgtgtcgtatcagcaggaaatcttctaagccatgttggtcatacc
atattgggcatgaacacagttcaactatacatgaaagttccagggagcagaacaccaggt
catcaggaaaataacaacttctgttcagttaacataaatattggcccaggtgactgtgaa
tggtttgttgttcctgaaggttactggggtgttctgaatgacttctgtgaaaaaaataat
ttgaatttcctaatgggttcttggtggcccaatcttgaagatctttatgaagcaaatgtt
ccagtgtataggtttattcagcgacctggagatttggtctggataaatgcaggcactgtt
cattgggttcaggctattggctggtgcaacaacattgcttggaatgttggtccacttaca
gcctgccagtataaattggcagtggaacggtacgaatggaacaaattgcaaagtgtgaag
tcaatagtacccatggttcatctttcctggaatatggcacgaaatatcaaggtctcagat
ccaaagctttttgaaatgattaagtattgtcttctaagaactctgaagcaatgtcagaca
ttgagggaagctctcattgctgcaggaaaagagattatatggcatgggcggacaaaagaa
gaaccagctcattactgtagcatttgtgaagtggaggtttttgatctgctttttgtcact
aatgagagtaattcacgaaagacctacatagtacattgccaagattgtgcacgaaaaaca
agcggaaacttggaaaactttgtggtgctagaacagtacaaaatggaggacctgatgcaa
gtctatgaccaatttacattagctcctccattaccatccgcctcatcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (15)   
   Pfam (15)   
All databases (67)   

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