KEGG T02283: 100996145

Pan paniscus (bonobo): 100996145

Entry

100996145         CDS       T02283

Symbol

HSD17B6

Name

(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 6

K13369

17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]

Organism

pps Pan paniscus (bonobo)

Pathway

pps00140

Steroid hormone biosynthesis

pps00830

Retinol metabolism

pps01100

Metabolic pathways

pps01240

Biosynthesis of cofactors

Module

pps_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

pps_M00977

C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:pps00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100996145 (HSD17B6)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100996145 (HSD17B6)
Enzymes [BR:pps01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     100996145 (HSD17B6)
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     100996145 (HSD17B6)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     100996145 (HSD17B6)

SSDB

Motif

Pfam:

adh_short adh_short_C2 DUF1776 KR

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

Position

12:complement(32117696..32155740)

AA seq 317 aa
MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYIFITGCDSGFGNLLARQLDARGLRVLAAC
LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
LCEWLNTEDSMNMLKMNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQ
QYFDALYSIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTS
LADYILTRSWPKPAQAV

NT seq 954 nt +upstreamnt +downstreamnt
atgtggctctacctggcggccttcgtgggcctgtactaccttctgcactggtaccgggag
aggcaggtggtgagccacctccaagacaagtatatctttatcacgggctgtgactcgggc
tttgggaacctgctggccagacagctggatgcacgaggcttgagagtgctggctgcgtgt
ctgacggagaagggggccgagcagctgaggggccagacgtctgacaggctggagacggtg
accctggatgttaccaagatggagagcatcgctgcagctactcagtgggtgaaggagcat
gtgggggacagaggactctggggactggtgaacaatgcaggcattcttacaccaattacc
ttatgtgagtggctgaacactgaggactctatgaatatgctcaaaatgaacctcattggt
gtgatccaggtgaccttgagcatgcttcctttggtgaggagagcacggggaagaattgtc
aatgtctccagcattctgggaagagttgctttctttgtaggaggctactgtgtctccaag
tatggagtggaagccttttcagatattctgaggcgtgagattcaacattttggggtgaaa
atcagcatagttgaacctggctacttcagaacgggaatgacaaacatgacacagtcctta
gagcgaatgaagcaaagttggaaagaagcccccaagcatattaaggagacctatggacag
cagtattttgatgccctttacagtatcatgaaggaagggctgttgaattgtagcacaaac
ctgaacctggtcactgactgcatggaacatgctctgacatcggtgcatccacgaactcgg
tattcagctggctgggatgctaaatttttcttcatccctctatcttatttacctacatca
ctggcagactacattttgactagatcttggcccaaaccagcccaggcagtctaa

DBGET integrated database retrieval system