KEGG   REACTION: R00734
Entry
R00734                      Reaction                               
Name
L-tyrosine:2-oxoglutarate aminotransferase
Definition
L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026  C00082_C01179
Enzyme
2.6.1.1         2.6.1.5         2.6.1.9         2.6.1.57
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00350  Tyrosine metabolism
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn00401  Novobiocin biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00025  Tyrosine biosynthesis, chorismate => HPP => tyrosine
M00044  Tyrosine degradation, tyrosine => homogentisate
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.1
     R00734  L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
    2.6.1.5
     R00734  L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
    2.6.1.9
     R00734  L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
    2.6.1.57
     R00734  L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.6.1.57
   R03120  Aromatic amino acid <=> Aromatic oxo acid
    R00734  L-Tyrosine <=> 3-(4-Hydroxyphenyl)pyruvate
Orthology
K00811  aspartate aminotransferase, chloroplastic [EC:2.6.1.1]
K00812  aspartate aminotransferase [EC:2.6.1.1]
K00813  aspartate aminotransferase [EC:2.6.1.1]
K00815  tyrosine aminotransferase [EC:2.6.1.5]
K00817  histidinol-phosphate aminotransferase [EC:2.6.1.9]
K00832  aromatic-amino-acid transaminase [EC:2.6.1.57]
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
K05821  aromatic amino acid aminotransferase II [EC:2.6.1.58 2.6.1.28]
K11358  aspartate aminotransferase [EC:2.6.1.1]
K14454  aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14455  aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K15849  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [EC:2.6.1.1 2.6.1.78 2.6.1.79]
Reference
1  [PMID:11583838]
  Authors
Meganathan R
  Title
Ubiquinone biosynthesis in microorganisms.
  Journal
FEMS Microbiol Lett 203:131-9 (2001)
DOI:10.1111/j.1574-6968.2001.tb10831.x
Other DBs
RHEA: 15096

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