KEGG   REACTION: R02103
Entry
R02103                      Reaction                               
Name
xanthine:NAD+ oxidoreductase
Definition
Xanthine + NAD+ + H2O <=> Urate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00143  C00366_C00385
Enzyme
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00546  Purine degradation, xanthine => urea
M00958  Adenine ribonucleotide degradation, AMP => Urate
M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.4
     R02103  Xanthine + NAD+ + H2O <=> Urate + NADH + H+
Orthology
K00087  xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4]
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K11177  xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
K11178  xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
K13479  xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4]
K13480  xanthine dehydrogenase iron-sulfur-binding subunit
K13481  xanthine dehydrogenase small subunit [EC:1.17.1.4]
K13482  xanthine dehydrogenase large subunit [EC:1.17.1.4]
K13483  xanthine dehydrogenase YagT iron-sulfur-binding subunit
Other DBs
RHEA: 16672

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