KEGG   Rattus norvegicus (rat): 108348065
Entry
108348065         CDS       T01003                                 
Symbol
Hdac6
Name
(RefSeq) histone deacetylase 6
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04613  Neutrophil extracellular trap formation
rno05014  Amyotrophic lateral sclerosis
rno05034  Alcoholism
rno05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    108348065 (Hdac6)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    108348065 (Hdac6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108348065 (Hdac6)
  09165 Substance dependence
   05034 Alcoholism
    108348065 (Hdac6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    108348065 (Hdac6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    108348065 (Hdac6)
   04131 Membrane trafficking [BR:rno04131]
    108348065 (Hdac6)
   03036 Chromosome and associated proteins [BR:rno03036]
    108348065 (Hdac6)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     108348065 (Hdac6)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     108348065 (Hdac6)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     108348065 (Hdac6)
Membrane trafficking [BR:rno04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    108348065 (Hdac6)
Chromosome and associated proteins [BR:rno03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     108348065 (Hdac6)
SSDB
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var
Other DBs
NCBI-GeneID: 108348065
NCBI-ProteinID: NP_001413957
RGD: 619981
Ensembl: ENSRNOG00000048738
Position
X:17222538..17244373
AA seq 1152 aa
MTSTGQDSSTRQRKSRHNPQSPLQDSSATLKRGGKKGAVPHSSPNLAEVKKKGKMKKLSQ
PAEEDLIVGLQGLDLNSETRVPVGTGLVFDEQLNDFHCLWDDSFPENPERLHAIKEQLIL
EGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAGTYDSVYLHPNSY
SCACLATGSVLRLVDAVMGAEIRNGMAVIRPPGHHAQRSLMDGYCMFNHLAVAARYAQKK
HRIQRILIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTTGFGQGQ
GYTINVPWNQVGMRDADYIAAFLHILLPVAFEFQPQLVLVAAGFDALHGDPKGEMSATPA
GFAHLTHFLMGLAGGKLILSLEGGYNLHALAKGVSGSLHTLLGDPCPMLESPVAPCASAQ
TSISCTLEALEPFWEVLERSVEPQDEDEVEGDMLEDEEEEGHWEATALPMDTWPLLQNRT
GLVYDERMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHS
AEYVERLRATEKMKTRDLHREGANFESIYICPSTFACAQLATGAACRLVEAVLSGEVLNG
IAIVRPPGHHAEPDAACGFCFFNSVAVAARHAQVIAGRALRILIVDWDVHHGNGTQHIFE
EDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRAAGTGFTVNVPWNGPRMGDADYLATWHR
LVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGG
YNLTSISESMAACTHSLLGDPPPQLTSLRPPQSGALASISEVIQVHRKYWRSLRLMKMED
KEERSSSRLVIKKLPQSASPVSAKGMTTPKGKVLEAGMRKPTAALPTKESTLGQAKAKTA
KALLAQGQSSEQAAKGTTLDLATSKDTVGGATTDQCASVAATENSANQTTSGEEASGETE
SFGTSPSSNASKQTTGASPLHGAAAQQSPELGLSSTLELSSEAQEVQESEEGLLGEAAGG
QDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGSVQENW
VCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYLCQAYVHHEDLQDVKNAAH
QNKFGEGMPHLQ
NT seq 3459 nt   +upstreamnt  +downstreamnt
atgacctccaccggccaagattcttctaccaggcagcgaaagagtaggcacaatccccaa
tcgccccttcaggactccagcgccaccttgaagcgtggtgggaagaagggtgctgtaccc
cactccagccccaatctagcggaggtaaagaagaaaggcaaaatgaagaagctcagccaa
ccagctgaagaagacctaatcgttgggcttcaagggctggatctgaactctgagacaaga
gtaccagttggtactggattggtatttgatgaacagctaaatgacttccactgcctttgg
gatgacagcttccctgaaaaccctgagcggctccatgccatcaaagagcagctgatcctg
gagggcctcctgggccgctgtgtgtcctttcaggcccggttcgccgagaaggaggaactg
atgttggttcacagcctggaatacattgatctgatggagacaacccagtacatgaatgaa
ggagaacttcgagttcttgcaggcacctatgattccgtttatctgcatccgaactcatat
tcatgtgcctgcctagctacaggctctgtcctcaggctggtagatgcagttatgggggct
gagattcggaatggcatggccgtcatcaggcctcctggacaccatgctcagcgcagtctt
atggatgggtattgcatgttcaaccacctggctgtggctgcccgctatgcacaaaagaag
caccgcattcagaggattctcatcgtggactgggatgtgcaccatggtcaaggaacacag
ttcatcttcgaccaggaccccagtgtactctatttctccatccaccgctatgagcatggt
cggttctggccccaccttaaggcttctaactggtccactacaggctttggccaaggccaa
ggatataccatcaatgtaccttggaaccaagtggggatgcgggatgccgactacattgct
gctttcctgcacatcctgctgccagttgcctttgagtttcagcctcaactggtcctggtg
gccgctggatttgatgccctccatggagaccccaagggagagatgtctgccactccagca
ggatttgcccacctgacccatttccttatgggtttggcaggaggcaagttgattctgtct
ctggagggtggctataacctccatgccttggctaagggcgtcagtggctcactccacacc
cttcttggagatccttgccccatgttggagtcccctgttgcaccttgtgcaagcgcccag
acttctatctcctgcactctagaagcccttgaacccttctgggaagtccttgagagatca
gttgagccccaggatgaagatgaagtggaaggagacatgctagaggatgaagaggaggaa
ggccactgggaggccactgctctaccaatggatacatggccactgctccagaaccgcact
gggctggtctatgacgaaagaatgatgagtcactgcaacctgtgggacaatcatcatcct
gagacacctcagcgcatcctacgcatcatgtgtcacctggaggaggtgggccttgcagca
cgctgtctcatcctacctgctcggcctgccctggattctgaactccttacgtgccacagt
gcggagtatgtggaacgtcttcgggccacagaaaagatgaaaactcgggatctgcaccgt
gaaggtgccaactttgagtccatctacatctgccccagcacctttgcctgcgcacagctt
gccacaggcgctgcctgccgcctggtggaagccgtgctttcaggagaggttttgaatggc
attgcaatagtgcgccctccaggacaccatgcggagccagatgctgcttgtggtttctgc
tttttcaattctgtagctgtagctgctcgccatgcccaagtcattgctggacgtgccctg
aggatcctaatcgtggattgggatgttcaccatgggaatggaactcagcacatatttgag
gaagaccccagtgtattatacgtgtccctgcaccggtatgaccgtggtactttcttcccc
atgggggatgagggtgccagtagccaagtagggcgagctgcaggtacaggcttcactgtc
aatgtgccctggaatgggccccgcatgggggatgctgattacctggctacgtggcatcgg
ctggtacttcccatcgcctatgagtttaacccagagctggtgctgatatcagctggcttt
gatgctgcccaaggggacccactgggaggctgccaagtgacacctgagggttatgcccac
ctcacccacctgctgatgggccttgctggtggccgtattattcttattctggagggtggc
tacaacttgacatccatctctgaatctatggctgcctgcacccattccctccttggagac
ccaccaccccagcttacttcgctccgacctccccagtcaggagccctggcttcaatcagt
gaggtcatccaagtgcatcgcaaatactggcgcagtttgcggttaatgaagatggaagac
aaggaagaacgctctagttctaggcttgtcatcaagaagctgccccagtcagctagtcct
gtgtccgctaagggaatgaccacaccaaaaggaaaggttctcgaagcaggcatgaggaag
cccacagcggcattacctacaaaagagtcgactctaggccaggctaaagcaaagacagct
aaggcattgctcgcccagggccagtcctcagaacaagctgctaagggaactacactggat
ctggccacctcaaaggacactgtgggaggtgccacaactgaccagtgtgcttcagtagca
gctacagaaaactcagctaaccagaccacgtcaggggaggaggcttcaggagaaactgag
tcattcggaacttctccatcctcaaatgccagcaagcagaccacaggagcttcacctctg
cacggagccgcagcccagcagtcccccgagcttgggctttccagcactttggagctaagc
agtgaagctcaggaagtccaagaatccgaggagggcctactaggagaagcagctggaggt
caggacatgaacagcttgatgctgacacaaggatttggggactttaatacccaggatgta
ttttatgccgtgactccactatcctggtgtccccacttgatggcggtgtgccccattcct
gcagcaggcctagatgtgtcccaaccttgtaagacctgtggatcggttcaggagaactgg
gtgtgtctgacttgttatcaggtgtactgcagtcgctatgtcaatgcccatatggtctgc
caccatgaagcctctgaacaccctctggtcctcagctgtgttgacctgtctacctggtgt
tacctctgtcaggcctatgtccaccacgaggatctccaagatgtgaagaacgctgcccac
cagaacaagtttggggagggcatgccgcacttgcagtaa

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Ontology (6)   
   KEGG BRITE (6)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (10)   
   RefSeq(nuc) (6)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (37)   

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