KEGG   Rattus norvegicus (rat): 114029
Entry
114029            CDS       T01003                                 
Symbol
Megf8
Name
(RefSeq) multiple epidermal growth factor-like domains protein 8 precursor
  KO
K23664  multipile epidermal growth factor-like domains protein 8
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04340  Hedgehog signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    114029 (Megf8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:rno04990]
    114029 (Megf8)
Domain-containing proteins not elsewhere classified [BR:rno04990]
 Laminin domain-containing proteins
  Laminin EGF-like domain-containing proteins
   114029 (Megf8)
SSDB
Motif
Pfam: Kelch_3 Kelch_4 Kelch_5 Kelch_1 Kelch_6 CUB EGF_CA Laminin_EGF EGF_3 PSI EGF_2 PSI_integrin hEGF EGF
Other DBs
NCBI-GeneID: 114029
NCBI-ProteinID: NP_446080
RGD: 621190
Ensembl: ENSRNOG00000052687
UniProt: R9PXW3
Position
1:90030057..90079423
AA seq 2789 aa
MALGGALAAALALAFAVLGPLSHKVLAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWL
IEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLL
HLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSPGVCVCEPGWGGPDCGLQECSAYCGS
HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARVGAAGAFLSPPG
LLAVFGGQDLNKALGDLVLYNFSTNTWESWDLTPAPAARHSHVAVAWAGFLVLMGGELAN
GLLTNDVWAFSPLGGGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFS
SGLFRFRLDHTSRGYWEQVIPAGGRPPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRV
NSTELFHVDRRVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDG
IFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDL
MAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQGACQSAPPPGTPSGACPAA
SCLGLGRLLSDCQACLAFSSPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGW
WGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSAETDVSL
VYRGFIYPMLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVGRWVAQQEKET
RRLQRPGSSRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFL
EPYRSLACSSYSSCLGCLADQGCGWCLNSATCHLRQGRAHCEDDGNGESLLVLVPALCPL
CEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCL
ANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCHGFLTCHECLQSHE
CGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRL
GLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLG
WTSDLPPPTPAPGPPAPRCSRDCGCNFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFG
NATGSGGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCF
RECGGRALLTNVSSVALGSRRFGGLLPPGGGTARAGPGLSYCVWVVSATEALQPCAPGTL
CPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQAL
SGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWA
GPHCRMALCPENCNAHTGAGICNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLS
ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGG
PGPSPRSFHAAAYVPAGRGAMYLLGGLTAGGITCDFWVLNLTTLQWRQEKAPQSIELPAV
AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYH
EATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKPRPRLFHASALLGDT
MVVLGGRSDPDEFSSDVLLYQVNCNTWLLPDLTRPAFVGSPMEESVAHAVAAVGSRLYIS
GGFGGVALGRLLALTLPPDPCRLLPSPEACNQSGACTWCHGACLSGDQAHRLGCGVPPCS
PMPRSPEECRRLRTCSECLARHPRTLQPGDGEASVPRCKWCTNCPEGACIGRNGSCTSEN
DCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTC
FSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPS
YLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLS
GPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNVT
GVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNH
TKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARREPEKYSLDPEEI
EAWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDGKCTKCQCNGHADTCNEQDGTG
CPCQNNTETGVCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPT
SQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVA
PDTGVHTVHIQPPPPPPPPPPPADGVPRVASDLGGLGTGSGSGSPVEPRVREVWPRGLIT
YVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGL
LFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRP
FAKVTVCFPPDPAGPAPAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAL
PATTAGLRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGG
SGGAGGSGHGGGGGRKGLLSQDNLTSMSL
NT seq 8370 nt   +upstreamnt  +downstreamnt
atggccttgggcggagctctggccgcggcccttgcactggccttcgctgtgctggggccg
ctgtcccacaaggtcctggccggtgactgcaaggggcagcggcaggtgctacgggaggca
ccaggcttcgtgacggatggtgcgggcaactacagcgtcaatggcaactgcgagtggctt
atcgaggcaccgagccctcagcaccggatcctgctggacttccttttcctggacacagag
tgcacttatgactacctctttgtgtatgatggtgactcaccccaaggcccgctgcttgct
agtctgagtgggagcacccggcccccacccatcgaggcatcctcaggcaagatgctgctc
catctcttcagtgatgccaactacaacctgctgggctttaacgcctccttccgcttctcc
ctgtgtcctggaggttgccagaaccacgggcagtgcaagtctccaggagtgtgtgtctgc
gagccaggctgggggggtccagactgtggcctgcaggagtgctcagcctactgtggtagc
cacggtacctgtgcctcgaccctgggaccatgccgctgtgagcctggattcctgggacgg
gcctgtgacctgcacttgtgggagaaccagggggctggctggtggcacagtgtgagtgcc
ggggaccccgccttctctgcccgagttggggcagctggtgccttcctgtctccaccaggg
ctgctggctgtctttggaggtcaggaccttaacaaggccctgggggatcttgtcctgtac
aacttctccaccaacacctgggaatcctgggatctgacgcctgctccggccgcccgtcac
tcccacgtggccgtggcctgggccggcttcctggtgctgatgggtggtgagctggccaat
ggcttgctaaccaacgatgtgtgggcctttagccccctgggtggaggccactgggagctc
ctggcaccacctgcttccagttcctctgggcccccagggctggcaggccatgcagcagct
ctggtagatgacatctggctgtatgtgtccggtggccgcactcagcatgacctcttttct
tctggcctcttccgcttccgcctggaccacaccagcaggggctactgggagcaggtgatc
cctgcaggtgggcggccccctgctgccactggccactctatggtgttccacgccccgtcc
cgtaccctgctggtccatggtggacaccggccttccactgcccggttttccgtgcgggtg
aattccaccgagctcttccacgtggaccgccgtgtgtggaccacgctgaagggccgggat
gggctccagggtccacgggagagagccttccacacagccagtgttctaggaaactacatg
gtggtctatgggggcaatgtgcacacccattaccaggaggaaaagtgttacgaagatggc
atcttcttctaccaccttggttgccaccaatgggtgtcgggggccgaacttgccccacca
gggacccctgaaggtcgagcagcgccccctagtggtcgttactcacatgtggcagctgtt
ctcggtggcagtgtcctgctggtggctgggggatacagtggccggcctcgtggggacttg
atggcctacaaggtgccccccttcgtgtttcaggcacccgccctggattaccacttggac
tactgttccatgtacacagaccacagtgtgtgctcccgggaccccgaatgtagctggtgt
cagggtgcttgccaatccgcaccccctcccgggactccctcaggagcttgtcccgcagcc
agctgcctgggcctaggccgcctactgagtgactgccaggcatgcctggccttcagcagc
cccacggctcctccccgaggacctggcaccctaggttggtgtgtgcacaacgagagctgc
cttccccggccagagcaggcacgctgccgaggggagcagatctcaggcactgtgggctgg
tgggggccagcacccgtctttgtcacttccctggaggcttgtgtcacccagagcttcctc
cctggcctgcacctgctcaccttccagcagccacccaacgcctctcagcctgacaaggtc
tccattgtccgaagtacaactatcaccttgacccccagcgcggagacagatgtgtccctg
gtctaccgaggcttcatctacccgatgctgccaggaggaccaggtggccctggggccgaa
gatgtggctgtgtgggctcgggcccagcgcctccatgtcctggcccggatggccagaggc
cctgacactgagaacatggaagaggtgggacgctgggtggctcagcaggagaaggagaca
cggcgtctgcagcgccccggctctagtcgcctcttcccactgcccggtcgaggcaacaag
tatgctgtggagatccgaggccagctcaatggctccgcaggccctgggcacagtgagctc
actctcctgtgggatcggactggagtgccgggtggcagtgagatctccttcttcttcctg
gagccctaccgctctttggcctgctcctcctactcctcctgtctgggctgcctggccgat
cagggctgtggctggtgcctcaacagtgccacctgtcacctgcgtcagggcagggcccac
tgtgaggatgacgggaacggcgagtccttgctggtgctggtgcctgccctctgtccactc
tgtgaggagcatcgtgactgccatgcctgcacccaggaccccttttgtgagtggcatcag
agcaccaaccgcaaaggtgacgcagcctgcagccggcgaggccggggccgaggcgctctg
aagaatcccgaggaatgccccccactctgcagccaacgcctgacctgtgaggactgcctg
gccaactctagccagtgcgcctggtgccagtcaactcacacctgcttcctgtttgctgcc
tacctggcccggtacccacacgggggctgccgtggctgggacgacagtgtgcattcagag
ccacgctgcaggagctgccacggatttttgacttgtcacgagtgtctacagagccacgag
tgtggttggtgtggcaatgaagacaaccccactctgggacggtgcctacagggggacttc
tccggacccctgggtggggggaactgctccctgtgggtgggagagggcctggggctgcct
gtggctcttcctgctcgctgggcttatgcccgctgtccagatgtggatgaatgtcgcctg
ggtctggcgaggtgtcacccacgggcaacgtgcctcaacacgcctctcagctatgagtgt
cattgccagcgcggctaccagggtgatggcatcacacactgtaaccgcacgtgcctggaa
gactgtggccacggtgtgtgtagcggtcccccggacttcacttgcgtgtgtgacctgggt
tggacctcagatttgccaccacccacacctgccccaggaccccctgccccacgctgctct
cgagactgtggctgcaactttcacagtcattgccgccggcggggacctggctactgtgat
gagtgccaggactggacatggggggaacactgtgaacggtgccggcctggcagctttggc
aatgcaacgggctctggtggctgccgaccctgccagtgtaacgggcatggagacccacgt
cgtggccactgtgacaacctcagtgggctctgcttctgccaggaccatactgaaggtgcc
cactgtcagatttgctctccaggatactatggggacccccgagctggtggctcctgcttc
cgggagtgtgggggtcgtgccctcctcaccaatgtgtcctcagtggctctgggctctcgc
cgctttgggggacttctgcctccaggtggtgggacagcaagagctggacccggcctgtcc
tactgtgtgtgggttgtctcagccacagaagcgctgcagccctgtgcccctgggaccctc
tgtcccccactcaccctcaccttctctccagacagcagcaccccttgcacactgagctat
gtcctggcctttgatggattcccacgctttctggacactggggtcgtccagtcagaccgg
agcctcatagctgccttctgtggtcagcggcgggacagacctctcaccgtgcaggcttta
tctgggttacttgtgttgcactgggaggccaatggctcctcctcctggggattcaatgct
tccgtgggctctgcccgatgtggatcaggaggccctggcagttgccctgtccctcaggag
tgtgtgccccaggatggggctgcaggtgctgggctctgccgatgtcctcagggctgggct
gggcctcactgccgcatggctctgtgtcctgagaactgcaacgcccacacgggggcaggg
atttgtaaccagagcctaggtgtgtgcatctgtgctgagggctttggtggcccagactgt
gccacgaagctggatggtgggcagttggtctgggaaacactcatggacagccgcctctca
gctgacactgctagtcgcttccttcaccgcctggggcatactatggtagagggacctgat
gctactttgtggatgtttgggggactgggtctgccgcagggcctgctgggaaacttgtat
aggtattcagtcagtgagcgcaggtggacacagatgctggcaggagctgaggatgggggc
ccaggcccatcaccccgctcctttcacgcagctgcctatgtacctgctggccgtggtgcc
atgtacctgctggggggcctcacagctgggggcatcacctgtgacttctgggtccttaac
ctcactaccctacagtggagacaggagaaggcccctcagagcatagagctgccagcagtc
gctggtcacacccttactgcccgtcgaggcctgtctctgctcttggtgggtggctactcc
cctgaaaatggcttcaaccagcagttgttggagtaccagctggcaaccggcacgtgggtg
tctggagcccagagtgggacgcccccaacaggtctctatggccattctgcggtctaccat
gaggccaccgactccctctatgtgtttgggggtttccgcttccatgtggaattggcggcg
ccttctccggagctctactccctgcactgtcctgaccgcacctggagcttgctggcacct
tctcagggggccaagccccggccccggctcttccatgcctcagccctgctgggggacacc
atggtggtcctcggggggcgctcggaccccgatgaattcagcagtgatgtcctgctctac
caggtcaactgcaacacctggctcctgcctgacctcacccgtccagcctttgtggggtcc
ccgatggaggagtccgtggctcacgcagtggcagcagtgggtagccgcctgtacatctct
ggaggatttgggggagtagccttgggccgcctgctggcattaaccctgccccctgacccc
tgtcgtctgctgccttcacctgaagcttgcaaccagtctggggcctgcacctggtgccat
ggtgcttgcctgtctggggaccaggcccacagactgggttgtggggtgcccccttgctcc
ccaatgcctcgctcgcctgaggaatgtcggagactgcggacctgcagtgagtgcctggcc
cgccatcctcggaccctgcagcctggagatggagaggcatccgttccccgctgtaagtgg
tgcactaactgcccagagggcgcctgcatcgggcgcaatgggtcctgcacctccgagaat
gactgtcgaatcaaccaacgagaggtcttctgggctggtaactgctcagaggccgcatgc
ggggctgccgactgtgagcagtgcacacgggagggaaagtgcatgtggactcggcaattc
aagaggactggggagactcggcgtatcctgtcagtgcagcccacctacgactggacttgc
ttcagccattctctgctgaatgtgtctcctatgccggtggagtcctcacccccactgccc
tgtcccaccccctgtcacctcctccccaattgcacatcctgcctggcctccaagggtgca
gatggaggctggcagcactgtgtgtggagcagcagcctccagcagtgtctgagcccctcc
tacctgcccttacgctgtatggctggaggctgtgggcggctgcttcgggggccagagagc
tgctccctgggctgtgctcaggctacgcagtgcgccctgtgtctgcgaagaccccactgt
ggctggtgtgcctgggggggacaggatggaggtggccactgcatggaaggtggtctcagt
ggcccccgagatgggctcacgtgtggacgtcctggggcatcctgggccttcctgtcctgc
ccccctgaggacgagtgtgcaaacgggcaccatgactgcaatgagactcagaactgccac
gaccagccccacggctacgagtgcagctgcaagacaggctacaccatggacaatgtgact
ggcgtctgccgccctgtgtgtgcccagggctgtgtgaacggctcctgtgtggagcctgat
cactgccggtgtcactttggctttgttggccgcaattgctccacagagtgtcgttgcaat
cgccacagtgagtgtgctggcgttggagcacgggatcactgcctgctgtgccggaaccac
accaagggtagccactgtgagcagtgtctcccactgtttgtgggttcggctttgggtggc
gggacctgccggccatgccatgccttctgtcgagggaacagccatgtgtgtgtctccagg
aaagagctagaaatggccagaagggagccagagaagtactcactggatccagaggagatt
gaagcctgggtggcagaagggcctagtgaagatgaagctgtgtgtgtgaactgccagaac
aacagctacggagacagatgtgagagctgcctgcacggctacttcctcctggacgggaaa
tgcaccaagtgccagtgcaatggccacgctgacacctgtaacgagcaggacggaacagga
tgcccatgtcagaacaacacagagacaggcgtctgccagggcagctctcctagtgaccgc
cgagactgctacaagtaccagtgtgctaagtgccgggagtcattccacgggagcccactg
ggtggccagcagtgttaccgactcatctcggtggagcaggagtgctgcctggaccccact
tcccagaccaactgcttccatgagccgaagcgccgggccttgggtcctggccgaactgtg
ctgtttggcgtccaacccaagttcaccaatgtggacatccgcctgacactagacgtgacc
ttcggtgctgtggacctctatgtctccacttcctatgacacttttgtggtccgagtggcc
cctgacacaggtgtccacactgtgcacatccagccacccccacctcccccacctcctccg
cctcctgccgatggtgtacctcgtgtggcttcggacctaggaggactggggaccggaagt
ggatcaggttctccagtggagccacgagtccgcgaggtgtggccacggggcctgattacc
tatgtgacagtgacggaaccctcggcagtgctggtggtccgcagtgtgcgggacaggctg
gtgatcacctatccccatgagcaccacgccctcaagtccagccgcttctacctgctgctg
ctgggggtaggggatcccaacgggcctggggccaacggctcggcggactcacagggcctg
ctcttcttccggcaagaccaggcccacattgacctgttcgtcttcttctctgtcttcttt
tcctgcttcttcctcttcctctcactctgtgtgctcctctggaaggccaagcaggctctg
gaccagcggcaagagcagcgccggcacctgcaggagatgaccaagatggctagccgcccc
tttgccaaggtcacagtctgcttccctccagaccctgcgggcccagcacctgcctggaag
ccagctggcctcccgcctcctgccttccgccgctccgagccatttcttgcacctctactg
ctgacaggagctggggggccctggggacccatgggaggagggtgctgcccaccagctctc
cctgccaccacagctggcctacgagctgggcccattacccttgaacccacagaagatggc
atggctggtgtggccactctgctgctccagctacctggggggcctcatgctcccaatggg
gcctgccttgggtcagcccttgtcactctgcgtcataggctgcatgagtactgtggggga
agcgggggtgctgggggcagtggacatgggggtggtggaggccggaagggactgttaagt
caggacaatctcactagcatgtccctttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (8)   
   RefSeq(nuc) (6)   
   GenBank (1)   
   EMBL (1)   
Protein domain (14)   
   Pfam (14)   
All databases (38)   

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