KEGG   Rattus norvegicus (rat): 114700
Entry
114700            CDS       T01003                                 
Symbol
Cyp27b1
Name
(RefSeq) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
  KO
K07438  calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00100  Steroid biosynthesis
rno01100  Metabolic pathways
rno04928  Parathyroid hormone synthesis, secretion and action
rno05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    114700 (Cyp27b1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    114700 (Cyp27b1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    114700 (Cyp27b1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    114700 (Cyp27b1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.18  calcidiol 1-monooxygenase
     114700 (Cyp27b1)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP27 family
   114700 (Cyp27b1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 114700
NCBI-ProteinID: NP_446215
RGD: 69192
Ensembl: ENSRNOG00000046214
UniProt: O35132
Position
7:64756626..64761570
AA seq 501 aa
MTQAVKLASRVFHRVQLPSQLGSDSVLRSLSDIPGPSTPSFLAELFCKGGLSRLHELQVH
GAARYGPIWSGSFGTLRTVYVADPALVEQLLRQESHCPERCSFSSWSEHRRRHQRACGLL
TADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDSVVSDLVRRLRRQRGRGSGLPDLVLDVA
GEFYKFGLEGIGAVLLGSRLGCLEAEVPPDTETFIEAVGSVFVSTLLTMAMPSWLHRLIP
GPWARLCRDWDQMFAFAQKHVEQREGEAAVRNQGKPEEDLPTGHHLTHFLFREKVSVQSI
VGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHSEITGAVNPGSYAHLQATALSQL
PLLKAVIKEVLRLYPVVPGNSRVPDRDICVGNYVIPQDTLVSLCHYATSRDPAQFREPNS
FNPARWLGEGPAPHPFASLPFGFGKRSCIGRRLAELELQMALAQILTHFEVLPEPGALPV
KPMTRTVLVPERSIHLQFVDR
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgacccaggcagtcaagctcgcctccagagtcttccatcgagtccaactgccttctcag
ctgggcagtgactcggttctccggagtttatctgatatccctgggccctctacacctagc
ttcctggctgaactcttctgcaaaggggggctgtccaggctacatgaactgcaggtgcat
ggcgctgcgcggtacgggccaatatggtccggcagcttcgggacacttcgcacagtttat
gtggccgaccctgcacttgtagagcagctcctgcgacaagaaagtcattgtccagagcgc
tgtagtttctcatcttggtcagagcaccgtcgccgccaccagcgggcttgcgggttgcta
acggcggatggtgaagaatggcagaggctccgaagtctcctggccccgctactcctccga
cctcaagcagccgccggctatgctggaactctggacagcgtggtcagtgacctcgtgcga
cgactaaggcgccagcggggacgtggctctgggctaccggacctagttctggacgtggcg
ggagagttttacaaatttggcctagaaggcataggcgcggtgctgctgggatcgcgcctg
ggctgcctggaggctgaagttcctcccgacacagaaaccttcattgaggccgtgggctcg
gtgtttgtgtctacactcttgaccatggcaatgcccagttggctgcaccgccttataccc
ggaccctgggcccgcctctgcagagactgggatcagatgtttgcctttgcccagaagcac
gtggagcagcgcgaaggcgaagctgccgtgaggaaccagggaaagcctgaggaggatttg
ccaacggggcatcacttaacccacttcctttttcgggaaaaggtgtctgtccagtccata
gtgggaaatgtgacagagctactactggctggagtggacacggtatccaatacgctctcc
tgggcactctatgagctctcccggcacccggaagtccagtctgcactccactctgagatc
acaggcgctgtgaaccctggctcctatgcccacctccaagccactgctctgtcccagcta
cccctgctaaaggctgtgatcaaagaagtgttgagattgtaccctgtggtacctgggaac
tcccgtgtcccagacagagacatctgtgtaggaaactatgttattccccaagatacactg
gtttccctctgtcactatgccacttcaagggaccccgcccagtttcgggaacccaactct
tttaatccagctcgatggcttggagagggtccagccccccacccatttgcatctcttcct
tttggctttggcaaacgaagttgcatagggagacgcttggcagagctcgagctacaaatg
gcgttggcccagatcttgacccattttgaggtgctgcctgagccaggtgctcttccagtc
aaacccatgacccggactgtcctggtacctgagaggagcatccatctccagtttgtagac
agatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (36)   

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