KEGG   Rattus norvegicus (rat): 114846
Entry
114846            CDS       T01003                                 
Symbol
Gsto1
Name
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    114846 (Gsto1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    114846 (Gsto1)
   00982 Drug metabolism - cytochrome P450
    114846 (Gsto1)
   00983 Drug metabolism - other enzymes
    114846 (Gsto1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114846 (Gsto1)
   05204 Chemical carcinogenesis - DNA adducts
    114846 (Gsto1)
   05207 Chemical carcinogenesis - receptor activation
    114846 (Gsto1)
   05208 Chemical carcinogenesis - reactive oxygen species
    114846 (Gsto1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114846 (Gsto1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    114846 (Gsto1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    114846 (Gsto1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    114846 (Gsto1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     114846 (Gsto1)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   114846 (Gsto1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N GST_C GST_C_3 GST_C_2 Glutaredoxin GST_C_5
Other DBs
NCBI-GeneID: 114846
NCBI-ProteinID: NP_001007603
RGD: 70952
Ensembl: ENSRNOG00000028746
Vega: OTTRNOG00000000845
UniProt: A6JHR8 F7F9Z0
Position
1:256662377..256672515
AA seq 241 aa
MSGASARSLGKGSAPPGPVPEGQIRVYSMRFCPFAQRTLMVLKAKGIRHEIININLKNKP
EWFFEKNPFGLVPVLENTQGHLITESVITCEYLDEAYPEKKLFPDDPYEKACQKMTFELF
SKVPSLVTSFIRAKRKEDHPGIKEELKKEFSKLEEAMAKKRTAFFGGNSLSMIDYLIWPW
FQRLEALELNECIDHTPKLKLWMATMQEDPVASSHFIDAKTYRDYLSLYLQDSPEACDYG
L
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtccggggcgtccgccaggagcctggggaagggaagcgcgccccctggcccggtcccg
gagggccagatccgagtctacagcatgaggttctgtccctttgctcagaggacgctgatg
gtcctgaaggccaagggaatccggcatgaaatcatcaacatcaacctgaagaataagccc
gagtggttctttgagaagaatccctttgggctggtgccggttctggagaacactcagggt
cacttgatcactgaatctgtcatcacttgcgagtacctggatgaagcatacccggagaag
aagttattcccagatgacccgtacgagaaagcttgccagaagatgacctttgagttattc
tcaaaggtgccgtctctggttacgagttttattagggcgaagagaaaggaagaccatccg
ggcataaaggaagaactgaagaaagagttcagcaagctagaagaggctatggctaaaaag
aggacagccttcttcggtgggaattcgctctcaatgatcgattatcttatttggccgtgg
tttcagcgactggaagcactggagctcaatgagtgtatagaccacaccccaaaactcaag
ctctggatggcaaccatgcaggaagaccccgtggcatcatcccacttcattgatgccaag
acctaccgtgattacttaagtctctacctacaggacagccccgaggcctgtgattatggg
ctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (8)   
   Pfam (8)   
All databases (113)   

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