KEGG   Rattus norvegicus (rat): 114858
Entry
114858            CDS       T01003                                 
Symbol
Shc3
Name
(RefSeq) SHC-transforming protein 3
  KO
K17448  SHC-transforming protein 3
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno01522  Endocrine resistance
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04062  Chemokine signaling pathway
rno04072  Phospholipase D signaling pathway
rno04510  Focal adhesion
rno04650  Natural killer cell mediated cytotoxicity
rno04722  Neurotrophin signaling pathway
rno04910  Insulin signaling pathway
rno04915  Estrogen signaling pathway
rno04917  Prolactin signaling pathway
rno04926  Relaxin signaling pathway
rno04935  Growth hormone synthesis, secretion and action
rno05034  Alcoholism
rno05100  Bacterial invasion of epithelial cells
rno05214  Glioma
rno05220  Chronic myeloid leukemia
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    114858 (Shc3)
   04014 Ras signaling pathway
    114858 (Shc3)
   04072 Phospholipase D signaling pathway
    114858 (Shc3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114858 (Shc3)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    114858 (Shc3)
   04062 Chemokine signaling pathway
    114858 (Shc3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    114858 (Shc3)
   04915 Estrogen signaling pathway
    114858 (Shc3)
   04917 Prolactin signaling pathway
    114858 (Shc3)
   04926 Relaxin signaling pathway
    114858 (Shc3)
   04935 Growth hormone synthesis, secretion and action
    114858 (Shc3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    114858 (Shc3)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114858 (Shc3)
   05226 Gastric cancer
    114858 (Shc3)
   05214 Glioma
    114858 (Shc3)
   05220 Chronic myeloid leukemia
    114858 (Shc3)
   05224 Breast cancer
    114858 (Shc3)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    114858 (Shc3)
  09165 Substance dependence
   05034 Alcoholism
    114858 (Shc3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114858 (Shc3)
   01522 Endocrine resistance
    114858 (Shc3)
SSDB
Motif
Pfam: PID SH2 PGM_PMM_IV
Other DBs
NCBI-GeneID: 114858
NCBI-ProteinID: NP_001099213
RGD: 69348
Ensembl: ENSRNOG00000014366
UniProt: G3V7V0 A6J6U1
Position
17:13803980..13924433
AA seq 594 aa
MLPRTKYNRFRNDSVTSVDDLLHSLSVSGSGGKVSAEPAASPYLVSGEALRKAPDDGPGS
LGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGGSATPGSRAPAAS
MSATRKSRASDEPLPRPPRGAPHASDQVLGSGVTYVVKYLGCIEVLRSMRSLDFSTRTQV
TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD
SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA
FELRFKQYLQCPSKIPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPNKMPPPGGFLDARL
KARPHAPDAAQFSGKEQTYYQGRHLGDAFGEDWQRAPTRQGSLDIYSTPEGKAHMVPVGE
TPTYVNTQPVPPQVWPAATSSTESSPRKDLFDMKPFEDALRNQPLGPVLSKAASVECISP
VTPRAPDAKMLEELNAEPWYQGEMSRKEAEALLQEDGDFLVRKSTTNPGSFVLTGMHNGQ
AKHLLLVDPEGTVRTKDRVFDSISHLITYHLESSLPIVSAGSELCLRQPVERKP
NT seq 1785 nt   +upstreamnt  +downstreamnt
atgcttccacgcaccaagtacaaccgcttcaggaatgactcggtgacatcggtcgatgac
cttctccacagcctgtcggtgagcggcagcggcggcaaggtctcggcggagcccgcggcg
agcccctacctggtgtcgggcgaggcgctgcgcaaggcgccggacgatgggcccggcagc
ctgggccacctgctccacaaggtgtcccacttgaaactctccagctccggcctgcgtggc
ctgtcgtcggccgcccgggagcgggcaggagcgcggctctcgggcagctgcagcgcgccc
agcctggcggccccggacggtggcagcgcgacccccgggtcccgtgccccggccgccagc
atgagcgccaccaggaagagccgggccagcgacgagccgttgcccaggcccccgcggggc
gcgccgcacgccagcgaccaggtgctggggtcgggagtcacctatgtggtcaagtacttg
ggatgcatcgaagttctgcgctcaatgaggtctcttgacttcagtacaagaactcaggtt
accagggaagccatcagccgtgtctgcgaagctgtgccaggcgccaaaggagccttcaag
aagagaaagcctccgagtaaaatgctgtccagcatcctggggaagagcaacctccagttc
gcagggatgagcatctccctgaccatctccaccgccagcctgaacctgcgcactcctgac
tccaaacagatcatagcgaaccatcacatgcggtccatctccttcgcctcagggggagac
ccggacacaacagactatgttgcctacgtcgctaaggaccctgtgaatcgcagagcttgc
cacattctggaatgctgtgacgggctagcccaagatgtcatcggctccatcggacaagcc
tttgaactccggttcaagcagtatttgcagtgtccttccaagattcctgctctccaggac
cgaatgcagagtctggacgagccgtggactgaagaagagggagatggccccgatcacccg
tactacaacagcgttcccaacaagatgcctcctccaggagggtttctcgatgctcgattg
aaagccagaccccacgctcctgatgcagcccagttttcaggaaaagagcaaacttattac
cagggaagacacttaggagatgcattcggtgaagactggcagagagcacccaccaggcaa
ggctccttggacatctatagcacaccagaagggaaagctcacatggttcctgtaggagaa
acaccaacctatgtcaacacccagccagtcccaccacaggtttggccagcagcaaccagc
agcactgagagcagcccacggaaggacctctttgacatgaagccttttgaagatgccctc
agaaaccaacccctgggccctgtgttgagcaaagctgcgtctgtggagtgtatcagcccc
gttacacccagagccccggacgccaagatgctggaggagcttaatgctgagccctggtac
caaggcgagatgagcaggaaggaggcagaggctctactacaggaagatggagacttccta
gtcaggaagagtaccaccaaccccggctcctttgtcctcacaggcatgcacaatggccag
gccaagcacctgctgctggtggacccggaaggcacggtccggacgaaggacagggtcttt
gacagcatcagtcacctcattacttaccacctggagagcagcctgcccattgtctctgcc
gggagtgagctttgtctccggcaaccagtggagaggaaaccctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (21)   
   KEGG PATHWAY (21)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (36)   

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