KEGG   Rattus norvegicus (rat): 116598
Entry
116598            CDS       T01003                                 
Symbol
Pdia4
Name
(RefSeq) protein disulfide-isomerase A4 precursor
  KO
K09582  protein disulfide-isomerase A4 [EC:5.3.4.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04141  Protein processing in endoplasmic reticulum
rno04918  Thyroid hormone synthesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    116598 (Pdia4)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    116598 (Pdia4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    116598 (Pdia4)
   04131 Membrane trafficking [BR:rno04131]
    116598 (Pdia4)
Enzymes [BR:rno01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.4  Transposing S-S bonds
    5.3.4.1  protein disulfide-isomerase
     116598 (Pdia4)
Chaperones and folding catalysts [BR:rno03110]
 Protein folding catalysts
  Protein disulfide isomerase
   116598 (Pdia4)
Membrane trafficking [BR:rno04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    116598 (Pdia4)
SSDB
Motif
Pfam: Thioredoxin Thioredoxin_6 Thioredoxin_2 Thioredoxin_8 OST3_OST6 Thioredoxin_7 AhpC-TSA Calsequestrin TraF
Other DBs
NCBI-GeneID: 116598
NCBI-ProteinID: NP_446301
RGD: 619835
Ensembl: ENSRNOG00000006228
UniProt: P38659
Structure
Position
4:complement(78134144..78153191)
AA seq 643 aa
MKLRKAWLLVLLLALTQLLAAASAEDAHEDASDSENPIEDDDDEEEDEEDEDDLEVKEEN
GVWVLNDENFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDA
TSASMLASKFDVSGYPTIKILKKGQAVDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLTL
TKENFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTD
LAKRFDVSGYPTLKIFRKGRPFDYNGPREKYGIVDYMVEQSGPPSKEILTLKQVQEFLKD
GDDVVILGVFQGVGDPGYLQYQDAANTLREDYKFHHTFSTEIAKFLKVSLGKLVLMQPEK
FQSKYEPRMHVMDVQGSTEASAIKDYVVKHALPLVGHRKTSNDAKRYSKRPLVVVYYSVD
FSFDYRTATQFWRNKVLEVAKDFPEYTFAIADEEDYATEVKDLGLSESGEDVNAAILDES
GKKFAMEPEEFDSDALREFVMAFKKGKLKPVIKSQPVPKNNKGPVRVVVGKTFDAIVMDP
KKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLVIAKMDATANDITNDRYKVEGFPT
IYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL
NT seq 1932 nt   +upstreamnt  +downstreamnt
atgaagctccggaaagcttggctgttggtcctgctcttggcgctgacacagctgctggct
gctgcgagcgccgaagatgcgcacgaagatgcttcagattcagaaaatcccattgaggat
gacgacgacgaggaggaagatgaagaagatgaagatgacttggaagttaaggaagaaaat
ggtgtttgggtcctaaacgatgaaaacttcgataactttgtggctgacaaagatacagtg
ctcctggagttctatgcaccgtggtgtggacactgcaagcaatttgctccagaatatgag
aaaattgccagtactttgaaggataatgatcctcccattgctgttgcaaagattgacgcg
acctcagcatccatgttggccagcaaattcgatgtgagtggctaccccaccatcaagatc
ctgaagaagggacaggctgttgactatgacggctccaggacccaggaagaaattgttgcc
aaagtcagagaagtttcccagcctgattggacacctccacctgaagtcactcttacattg
actaaagagaactttgacgatgttgtaaataatgcagacatcattttggtggagttctat
gccccatggtgcggacactgcaagaaacttgcccctgagtatgagaaggctgccaaggag
ctcagcaagcgctctcccccaattcccttagccaaagttgatgccaccgaacagacagac
ctggctaagaggtttgatgtctctggctaccccactttgaaaatattccgcaaaggaagg
ccttttgactacaatggtccacgagagaaatatggaattgttgactacatggttgagcag
tctggacctccttccaaggagattctgaccctgaagcaggtccaggagtttctgaaggat
ggagatgatgtagtcatccttggagtctttcagggagtcggtgacccaggctacttgcag
tatcaggatgctgctaacaccctgagagaagattacaaatttcaccacactttcagcact
gaaatagctaagttcctgaaagtctccctggggaaactggtgctgatgcagcctgagaag
ttccagtccaagtatgagcccaggatgcatgtgatggatgttcagggctccacagaggca
tcagccattaaggactatgtggtgaaacatgccttgcccctagtgggccacaggaagact
tctaacgatgctaagcggtacagcaagcgccccctggtggttgtatactacagtgtggac
ttcagctttgattacagaactgctactcagttttggcgtaacaaagtcctagaggtggcc
aaggacttccctgagtacacattcgccattgctgatgaagaagactatgccacagaggtg
aaggacctgggactgagtgagagtggagaggacgtcaatgcagccatcctagatgagagt
gggaagaagtttgccatggagccagaggagtttgattcagatgctctccgagaatttgtc
atggctttcaaaaaaggaaaactaaagccagttatcaaatcacagccagttcccaagaac
aacaagggaccagtcagggtggtagtggggaagacctttgatgccattgtgatggacccc
aaaaaggacgtcctcattgaattctatgcaccgtggtgtgggcactgcaagcagctggag
cctgtctacaccagcctaggcaagaagtacaagggccagaaggacttggtcatcgccaag
atggatgctactgccaatgacatcaccaacgaccgatacaaggtggagggcttccccacc
atctattttgcccccagtggggacaaaaagaacccaattaagtttgagggtggcaacaga
gatctggagcatttgagcaagtttatcgatgaacatgccacaaagaggagcaggaccaag
gaagagctttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (32)   

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