KEGG   Rattus norvegicus (rat): 116601
Entry
116601            CDS       T01003                                 
Symbol
Atp2a1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04148  Efferocytosis
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04380  Osteoclast differentiation
rno04919  Thyroid hormone signaling pathway
rno04972  Pancreatic secretion
rno05010  Alzheimer disease
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    116601 (Atp2a1)
   04024 cAMP signaling pathway
    116601 (Atp2a1)
   04022 cGMP-PKG signaling pathway
    116601 (Atp2a1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    116601 (Atp2a1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    116601 (Atp2a1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    116601 (Atp2a1)
   04261 Adrenergic signaling in cardiomyocytes
    116601 (Atp2a1)
  09154 Digestive system
   04972 Pancreatic secretion
    116601 (Atp2a1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116601 (Atp2a1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116601 (Atp2a1)
   05017 Spinocerebellar ataxia
    116601 (Atp2a1)
   05022 Pathways of neurodegeneration - multiple diseases
    116601 (Atp2a1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    116601 (Atp2a1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    116601 (Atp2a1)
   05414 Dilated cardiomyopathy
    116601 (Atp2a1)
   05415 Diabetic cardiomyopathy
    116601 (Atp2a1)
Enzymes [BR:rno01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     116601 (Atp2a1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD CA109-like
Other DBs
NCBI-GeneID: 116601
NCBI-ProteinID: NP_478120
RGD: 621293
Ensembl: ENSRNOG00000047124
UniProt: Q64578 B4F7E5
Position
1:complement(190457198..190475410)
AA seq 994 aa
MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDICSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVADRAYTGREFDD
LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG
NT seq 2985 nt   +upstreamnt  +downstreamnt
atggaggccgcacactccaagtccacagaggaatgtttgtcctattttggggtgagcgag
accacaggccttaccccagaccaagttaagcggcatctggaaaaatacggccccaatgag
ctccctgctgaggaaggcaagtctctgtgggagttggtggtagagcagttcgaagacctg
ctggtgcggattctcctcctggctgcctgcatttcctttgtgctggcctggtttgaggaa
ggtgaggaaactgtcactgcctttgtggagccttttgtcattctcttgatcctcattgcc
aacgccattgtgggggtttggcaggaacggaatgcagagaatgccatcgaggcgctgaag
gaatatgaacccgagatggggaaggtctatcgggctgaccgaaagtcagtgcaaaggatc
aaggctcgggacatcgtccctggggacattgtggaggtggctgttggggacaaagtccct
gcagacatccgaatcctctccatcaaatccaccaccctccgggtcgaccagtccatcctg
acaggagagtctgtatctgtcatcaagcacacagaccctgtccctgatccccgagctgtc
aaccaggacaagaagaacatgctcttctcgggtaccaacattgcagccggcaaggccgta
ggcatcgtggccaccactggtgtgagtactgagattggcaagatccgagaccaaatggct
gccactgagcaggacaagaccccgcttcagcagaagcttgatgagtttggggaacagctg
tccaaggtcatctctctcatctgtgtggctgtctggcttatcaacattggtcacttcaac
gaccctgtccatgggggctcctggttccggggggccatttactacttcaagattgctgta
gccttggctgtggcagccatcccagaagggcttcctgctgtcatcaccacctgcttggcc
ttgggtacccgccggatggcaaagaagaacgccatcgtgaggagtttgccctctgtggag
accctgggctgtacctctgtcatctgttctgacaaaacagggaccctcaccaccaaccag
atgtcagtttgcaagatgttcatcattgacaaagtggatggggatatctgctcactgaac
gagttctccatcactggctctacttatgctcctgagggagaagttttgaagaatgataag
ccagtccgagcagggcagtatgacgggctggtggaacttgctaccatctgtgccctctgc
aatgactcctccttggactttaatgagaccaaaggtgtctatgagaaggtgggcgaggcc
accgagacagccctcaccaccttggtggagaagatgaatgtgttcaacacggaagtgaga
agcctctccaaagtggagcgggctaatgcctgcaactcggtgatccgccaactaatgaag
aaggaattcaccctggaattttcccgagacaggaagtctatgtctgtctactgctcccca
gccaagtcttcacgggctgctgtaggcaacaagatgtttgtcaagggtgcccctgagggc
gtcattgaccgctgtaactatgtgcgtgttggcacaacccgtgtgccactgacaggccct
gtgaaggagaagatcatgtcggtgatcaaggagtggggtactggtcgggataccctacgg
tgcctggcactggccacccgggacacaccccccaaacgggaggaaatggttctggatgac
tcagccaagttcatggagtatgagatggacctgacgtttgttggtgtggtgggcatgttg
gatccaccccgtaaggaggtcacaggctctatccagctgtgtcgtgatgccgggatccga
gtgatcatgatcactggggacaacaagggtaccgccatcgccatctgccgacgaattggc
atcttttcggagaatgaggaagtggcagaccgtgcctacactggccgtgagtttgatgat
ctgcccctggctgagcagcgggaagcctgcagacgcgcctgctgcttcgctcgtgtggag
ccctcacataagtccaagattgtggagtacctgcagtcctatgatgagatcacagccatg
acaggggatggtgtcaatgatgcccctgctctgaagaaggcggagattggcattgccatg
ggatctggtactgctgtggctaagactgcctccgagatggtactggctgatgataacttc
tccaccattgtggctgccgtggaggaaggccgtgccatctacaacaacatgaagcagttc
atccgctacctcatttcctccaatgtgggcgaggtggtctgtatcttcttgacagcagcc
ttggggctgcctgaggccttgatccctgtgcagctgctatgggtgaacttggtgactgat
gggctccctgctactgccctggggttcaacccacctgacctggacatcatggaccgtccc
cccaggagtcccaaggagcctcttatcagtggctggctctttttccgctacatggcaatt
gggggctacgtgggtgcagccactgtgggagcagctgcctggtggttcttgtatgcagag
gatgggcctcatgtcagctaccatcaactgactcatttcatgcagtgcactgagcataac
cctgaatttgatggcctggactgcgaggtctttgaagcccccgagcccatgaccatggcc
ttgtctgtgttggtgaccatcgagatgtgcaacgccctcaacagcctgtctgagaaccag
tccctactgcggatgccgccctgggtgaacatctggcttctcggttccatctgcctgtcc
atgtccctccacttcctcatcctctatgttgaccccctgccgatgatcttcaagctccgg
gccctggactttacccagtggctcatggtcctcaagatctcacttccagtcatcgggcta
gatgagcttctcaagttcattgctcggaactatctggagggataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (37)   
   RefSeq(nuc) (1)   
   GenBank (18)   
   EMBL (18)   
Protein domain (8)   
   Pfam (8)   
All databases (75)   

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