KEGG   Rattus norvegicus (rat): 117037
Entry
117037            CDS       T01003                                 
Symbol
Spam1
Name
(RefSeq) hyaluronidase PH-20 precursor
  KO
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00531  Glycosaminoglycan degradation
rno01100  Metabolic pathways
rno04142  Lysosome
Module
rno_M00076  Dermatan sulfate degradation
rno_M00077  Chondroitin sulfate degradation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    117037 (Spam1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    117037 (Spam1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:rno02042]
    117037 (Spam1)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    117037 (Spam1)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:rno00537]
    117037 (Spam1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     117037 (Spam1)
Bacterial toxins [BR:rno02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   117037 (Spam1)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Enzymes
   117037 (Spam1)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:rno00537]
 Enzymes
  117037 (Spam1)
SSDB
Motif
Pfam: Glyco_hydro_56
Other DBs
NCBI-GeneID: 117037
NCBI-ProteinID: NP_446419
RGD: 620547
Ensembl: ENSRNOG00000007231
UniProt: Q62803 A6IE93
Position
4:54268287..54278455
AA seq 512 aa
MGELQFKWLFWRSFAESGGTFQTVLIFLFIPYSLTVDYRATPVLSDTTFVWVWNVPTEAC
VENVTEPIDLSFFSLIGSPRKTAIGQPVTLFYVDRLGNYPHIDAQQTEHHGGIPQKGDLT
THLVKAKEDVERYIPTDKLGLAIIDWEEWRPTWMRNWTPKDIYRNKSIELVQAADPAINI
TEATVRAKAQFEGAAKEFMEGTLKLGKHIRPKHLWGFYLFPDCYNNKFQVDNYDGQCPDV
EKKRNDDLDWLWKESTGLYPSVYLKKDLKSSRKATLYVRYRVLESIRVSKVSDESNPVPI
FVYIRLVFTDHVSEYLLEDDLVNTIGEIVAQGTSGIIIWDAMSLAQRSAGCPILRQYMKT
TLNPYIVNVTLAAKMCSQTLCKEKGMCSRKTESSDAYLHLDPSSFSINVTEAGKYEVLGK
PEVKDLEYFSEHFKCSCFSKMTCEETSDMRSIQDVNVCMGDNVCIKATLGPNSAFHLLPG
KGLLLMTTLAHILHHLPHDIFVFPWKMLVSTP
NT seq 1539 nt   +upstreamnt  +downstreamnt
atgggagagttgcaatttaagtggctcttttggaggagctttgctgagtctgggggcaca
ttccaaacagtgttaatctttcttttcattccatattccttgactgtggattatagggca
acaccagttctgtcagatacaactttcgtttgggtctggaatgttccaactgaagcttgt
gtagaaaacgttactgaaccaatagatctgagcttcttctctttaattggaagcccccgg
aaaactgccatagggcagcctgtcacattattttatgttgatcgacttggtaactatcct
cacatagatgcacagcaaacagaacatcatggaggaatacctcagaagggggatttgaca
actcatttggtgaaagctaaggaagacgtagagcgttacataccaacagacaaactgggt
ttagctatcattgactgggaagaatggaggcctacctggatgagaaactggacacctaag
gatatttacaggaataagtctattgaattggtccaggcagctgatccagcaattaatatc
acagaagctactgtgagagccaaagcacaatttgaaggggcagctaaagagtttatggaa
gggactttaaaattggggaaacatattcgaccaaagcacttatggggtttttatctattt
cctgattgttataacaataaatttcaagtcgataactatgatggccaatgccctgatgtg
gaaaagaaacgaaacgatgatcttgactggctatggaaagaaagcacgggcctttaccca
tctgtctatttgaagaaagatttgaagtcgagtcgaaaagcaaccctttatgtccgctac
cgagttttagaatctatcagagtgtccaaagtttcagatgaatcgaatccagttccaatt
tttgtctatatccgtcttgttttcactgatcatgtctctgaataccttctagaggatgat
cttgtgaatacaattggtgaaattgttgctcagggtacctctggaattataatatgggat
gctatgtctttagcacaacgttcggcaggttgcccaatcctacgtcaatacatgaagaca
accctgaatccatacatagtcaatgtcaccctagcagccaaaatgtgcagtcaaacactt
tgtaaggagaaaggcatgtgttcgagaaaaacagaaagttcagatgcatatcttcacttg
gatccaagtagtttttctattaatgtaacagaagctggaaagtatgaagttcttggcaag
cccgaggttaaagacttggaatacttttctgaacattttaaatgcagctgttttagcaaa
atgacatgtgaggagacatctgatatgcgaagtatacaagatgtgaatgtgtgcatgggt
gacaatgtttgtataaaagccacgctaggacccaactcagcattccacctcctacctggc
aaaggcctcctccttatgacaacacttgctcacatcttgcaccatctaccacatgatatt
tttgtttttccgtggaagatgctagtcagtactccttag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (34)   

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