KEGG   Rattus norvegicus (rat): 117098
Entry
117098            CDS       T01003                                 
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial precursor
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00010  Glycolysis / Gluconeogenesis
rno00020  Citrate cycle (TCA cycle)
rno00620  Pyruvate metabolism
rno00785  Lipoic acid metabolism
rno01100  Metabolic pathways
rno01200  Carbon metabolism
rno01210  2-Oxocarboxylic acid metabolism
rno04066  HIF-1 signaling pathway
rno04922  Glucagon signaling pathway
rno05230  Central carbon metabolism in cancer
rno05415  Diabetic cardiomyopathy
Module
rno_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    117098 (Pdha2)
   00020 Citrate cycle (TCA cycle)
    117098 (Pdha2)
   00620 Pyruvate metabolism
    117098 (Pdha2)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    117098 (Pdha2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    117098 (Pdha2)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    117098 (Pdha2)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    117098 (Pdha2)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    117098 (Pdha2)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     117098 (Pdha2)
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N DUF2776
Other DBs
NCBI-GeneID: 117098
NCBI-ProteinID: NP_446446
RGD: 620095
UniProt: Q06437 A6HW52
Position
2:complement(232545550..232547098)
AA seq 391 aa
MRKMLATVLSQVFSGMVQKPALRGLLSSLKFSNDATCDIKKCDLYLLEQGPPTSTVLTRE
EALKYYRNMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACNVGLEAGINPTDHIITSYR
AHGLCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGVAL
ACKYLKNGQICLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNRYGMGTAIERSAAS
TDYHKKGFVIPGLRVNGMDILSVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRTREEVQNVRSKSDPIMLLRERMISNNLSSVEELKEIDADVKKEVEEAAQFATTDPEP
PLEDLANYLYHQNPPFEVRGAHKWLKFKSVS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgaggaaaatgctggccactgtgctgtctcaagtattttcaggaatggtccagaagcca
gctctcaggggactgctgtcatctcttaagttctccaacgacgccacctgtgacatcaag
aaatgcgacttgtacctgttggaacagggcccccccacctccactgtgctcaccagagag
gaggccctgaaatactaccggaacatgcaggtaattcggcgcatggagttgaaggccgac
cagctgtataagcagaaattcatccgtggtttctgtcacctgtgtgatgggcaggaagcc
tgcaatgtggggctggaggcagggataaatcccacagaccacatcatcacgtcctacaga
gctcatggcttgtgctacacgaggggactgtcagtgaagtccattctcgcagagctgact
ggacgcaaaggaggctgtgctaaaggcaagggaggctctatgcacatgtacgccaagaac
ttctatgggggcaatggcattgttggggcacaggtacccctgggagctggtgtggctctc
gcctgtaaatacctgaagaatggtcagatctgcttggctttgtatggcgatggtgcggct
aaccaagggcaggtatttgaagcttacaatatgtcagccttgtggaaattaccctgtgtt
ttcatctgtgagaataaccgctatggaatgggaacagctattgagagatcagcagccagt
actgattaccacaagaaaggctttgttatccctggactgagggtgaatgggatggatatt
ctcagtgttcgtgaggcgaccaagtttgcagctgatcactgcagatccggaaaggggccc
attgtgatggagttgcagacataccgttatcatggacacagtatgagcgatccagggatc
agttatcgtacacgagaagaagttcagaacgtgaggagtaagagtgatccaataatgctt
ctccgagagagaatgataagcaacaacctcagcagtgttgaagaattgaaagaaattgat
gcagatgtgaagaaagaagtcgaggaagcagctcagtttgctacaactgatccagaacca
cctctggaagatttagccaattacctctaccaccaaaatccaccatttgaagtccgtggt
gcacataaatggctgaagtttaagtctgtcagttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (12)   
   KEGG PATHWAY (11)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (47)   

Download RDF
DBGET integrated database retrieval system