KEGG   Rattus norvegicus (rat): 117276
Entry
117276            CDS       T01003                                 
Symbol
Pfkfb3
Name
(RefSeq) 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3
  KO
K01103  6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00051  Fructose and mannose metabolism
rno01100  Metabolic pathways
rno04066  HIF-1 signaling pathway
rno04152  AMPK signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    117276 (Pfkfb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    117276 (Pfkfb3)
   04152 AMPK signaling pathway
    117276 (Pfkfb3)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.105  6-phosphofructo-2-kinase
     117276 (Pfkfb3)
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.46  fructose-2,6-bisphosphate 2-phosphatase
     117276 (Pfkfb3)
SSDB
Motif
Pfam: 6PF2K His_Phos_1 AAA_33 KTI12 Zeta_toxin DIL SRP54 AAA_18 APS_kinase
Other DBs
NCBI-GeneID: 117276
NCBI-ProteinID: NP_476476
RGD: 619776
Ensembl: ENSRNOG00000018911
UniProt: O35552 A6JLS9
Position
17:71893320..71974526
AA seq 555 aa
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQ
IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
AEAMDDFMKRINCYEASYQPLDPDKCDRDLSFIKVIDVGRRFLVNRVQDHIQSRIVYYLM
NIHVQPRTIYLCRHGENEYNVQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQ
LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
TPVAYGCRVESIYLNVESVSTHRERSEAVKIQHFASVVRPSSYTELDFLSVESAKQDAKK
GPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQPLLGKA
CLRTVCHIFSKFSPY
NT seq 1668 nt   +upstreamnt  +downstreamnt
atgcctttggaactgacccagagccgggtgcagaagatctgggtgcctgtcgatcaccga
ccctcgttgcccagatcctgtgggccgaagctgaccaactccccaacggtgattgtgatg
gtggggctcccagcccggggtaagacttacatctccaagaagctgactcgctacctcaac
tggataggtgttccaacgaaagtgttcaatgtgggagaataccgacgggaggctgtgaag
caatacagctcttacaacttcttccgccctgacaatgaggaggccatgagagtccgaaaa
cagtgtgccttagctgccctgagagacgtcaaaagctacctgacaaaggaaggaggacag
attgcagtttttgatgccaccaatacgacgagagaaaggaggcacatgatccttcatttt
gccaaagaaaatgacttcaaggcatttttcatcgagtccgtctgtgacgaccctacagtt
gtggcctccaatatcatggaagtgaaaatctccagcccggattacaaagactgcaactcc
gcagaagccatggacgacttcatgaagaggatcaactgctacgaagccagctaccagcct
cttgaccctgataaatgtgacagggacctgtcattcatcaaagtgattgacgttggccgg
aggttcttggtgaacagagtgcaggaccacatccagagccgaatcgtgtattacctgatg
aacatccacgtgcagccccggaccatctacctgtgtcggcacggcgagaatgagtacaac
gtgcagggcaagattgggggcgactcaggcctgtccagcagaggcaagaagttcgccaat
gccctgagcaagttcgttgaagagcagaatctgaaggacctccgcgtgtggaccagtcag
ctgaaaagtaccatccagaccgcggaggccctaaggctcccctacgagcagtggaaggcg
ctcaatgagattgatgctggtgtgtgtgaggaactaacctatgaggagatcagagacacc
taccctgaggagtatgcactgcgtgagcaagacaaatactactaccgctatcccacaggc
gagtcctaccaggatcttgtccagcgcctggagcctgtgatcatggaattagagcgccaa
gagaacgtattggtcatctgtcaccaggctgtcctgcgctgcctactagcctacttcctt
gacaagagtgcagaggagatgccatacctgaaatgcccacttcacacagtcctgaaactg
acgcccgtggcgtatgggtgccgtgtggagtccatttacttgaatgtagaatcagtgagc
acgcatcgggagaggtcagaggctgtcaaaatacaacactttgccagtgtagtcagacct
tcctcttacaccgaacttgactttctgtctgtggagtccgcaaaacaggatgcaaagaag
ggacctaaccctctcatgagacgcaatagtgtcaccccactagccagccccgagcccacc
aaaaagcctcgcatcaacagctttgaggagcatgtggcttccacttctgctgccctgcca
agctgcctgcccccggaagtgcccacgcagctgcccggacaacctttgctagggaaagcc
tgtctacgaactgtctgtcacattttttcaaagttttctccttactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (30)   
   RefSeq(nuc) (10)   
   GenBank (10)   
   EMBL (10)   
Protein domain (9)   
   Pfam (9)   
All databases (74)   

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