KEGG   Rattus norvegicus (rat): 117519
Entry
117519            CDS       T01003                                 
Symbol
Keap1
Name
(RefSeq) kelch-like ECH-associated protein 1
  KO
K10456  kelch-like protein 19
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04120  Ubiquitin mediated proteolysis
rno05012  Parkinson disease
rno05200  Pathways in cancer
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    117519 (Keap1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117519 (Keap1)
   05208 Chemical carcinogenesis - reactive oxygen species
    117519 (Keap1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    117519 (Keap1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    117519 (Keap1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    117519 (Keap1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:rno04121]
    117519 (Keap1)
Ubiquitin system [BR:rno04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     117519 (Keap1)
SSDB
Motif
Pfam: Kelch_1 Kelch_6 Kelch_3 Kelch_2 BACK BTB Kelch_4 KLHL33-like_BTB_POZ
Other DBs
NCBI-GeneID: 117519
NCBI-ProteinID: NP_476493
RGD: 621619
Ensembl: ENSRNOG00000020878
UniProt: G3V8U2
Position
8:complement(28044555..28054042)
AA seq 620 aa
MQPEPKPSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQDGNRTFSYTLEDHT
KQAFGIMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGM
EVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLD
PSNAIGIANFAEQIGCTELHQRAREYIYMHFGEEEFFNLSHCQLATLISRDDLNVRCESE
VFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQI
FQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSG
LAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHSSVERYEPDRDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRL
NSAECYYPERNEWRMITPMNTIRSGAGVCVLHSCIYAAGGYDGQDQLNSVERYDVETETW
TFVASMKHRRSALGIAVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRLTSGRSGV
GVAVTMEPCRKQIDQQNCTC
NT seq 1863 nt   +upstreamnt  +downstreamnt
atgcagcccgaacccaagcctagcggggctccccgcagcagccagttcctgcccctgtgg
tcaaagtgcccggagggggcaggggacgcggtgatgtatgcatccacggagtgcaaggcg
gaggtgacgccctcgcaggatggtaaccgaaccttcagttacacactagaggatcacacc
aagcaggcttttggcatcatgaacgagcttcggctgagccagcagctctgtgacgtgacc
ctgcaggtcaaatatgaggacatcccagctgcccaattcatggcccacaaagtggtgctg
gcctcctccagcccagtctttaaagctatgttcaccaacgggcttcgggagcagggcatg
gaggtggtgtccattgaaggcatccaccccaaggtcatggagaggctaattgagttcgcc
tacacggcctccatctccgtgggcgagaagtgtgtgctgcatgtgatgaacggggcagtc
atgtaccagattgacagcgtggtccgagcctgcagcgacttcctcgtgcagcagctggac
cccagcaacgccatcggcatcgccaacttcgccgagcagatcggctgcacggaactgcac
cagcgtgctcgggagtatatctacatgcacttcggggaggaggagttcttcaacctgtca
cactgccagctggccacgctcatcagccgcgatgatctgaacgtgcgctgcgagtccgag
gtgttccatgcgtgcatcgactgggtcaaatacgactgcccgcagcggcgcttctacgtg
caggcactgctacgggccgtgcgctgccacgctctcacgccacgcttcctgcagacacag
ctgcaaaagtgcgagatcctgcaggccgacgcgcgctgcaaggactacctggtgcagatc
ttccaggagctcacgctgcacaagcccacacaagcggtgccctgccgggcgcccaaagtg
ggccgcctcatctacactgcgggcggttacttccgacagtcgctcagctacctggaggcc
tacaacccgagcaatggctcctggctgcgcctggcagacctacaggtgccccgcagtggg
ctggcgggctgcgtggtgggcgggctgctgtatgctgtgggcggccgcaacaactcgccg
gacggcaacactgattccagcgccctggactgctacaaccccatgaccaaccagtggtcg
ccctgtgcctctatgagcgtgccgcgcaaccgcatcggggtgggggtcatagatggccac
atctacgcagtcgggggttcccacggctgcatccaccacagcagcgtggagagatatgag
ccagatcgagacgagtggcacctagtcgcgccaatgttgacgcggaggatcggcgtgggc
gtggcagtgctcaaccgcttgctgtatgcagtggggggctttgatgggactaaccggctt
aactcggcagaatgttactacccggagaggaatgagtggcggatgattacaccaatgaat
accatccggagcggggccggggtctgtgtgctgcacagctgcatctatgccgcaggaggc
tacgatgggcaggaccagctgaacagcgtggaacgctacgacgtggagacagagacctgg
actttcgtagcctccatgaagcatcgccggagcgcgctggggattgctgtgcaccagggc
aggatctacgtcctcggaggctacgatggccacacttttctggacagtgtggaatgctat
gacccagacactgatacctggagtgaagtgacccgcttgacatctggccgcagtggggtg
ggtgttgctgtcaccatggaaccctgtcggaagcaaattgatcaacaaaactgtacctgc
tga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
Protein domain (8)   
   Pfam (8)   
All databases (34)   

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