KEGG   Rattus norvegicus (rat): 140583
Entry
140583            CDS       T01003                                 
Symbol
Chek1
Name
(RefSeq) serine/threonine-protein kinase Chk1
  KO
K02216  serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04110  Cell cycle
rno04115  p53 signaling pathway
rno04218  Cellular senescence
rno05166  Human T-cell leukemia virus 1 infection
rno05170  Human immunodeficiency virus 1 infection
rno05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    140583 (Chek1)
   04115 p53 signaling pathway
    140583 (Chek1)
   04218 Cellular senescence
    140583 (Chek1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    140583 (Chek1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    140583 (Chek1)
   05170 Human immunodeficiency virus 1 infection
    140583 (Chek1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    140583 (Chek1)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:rno03400]
    140583 (Chek1)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     140583 (Chek1)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   140583 (Chek1)
DNA repair and recombination proteins [BR:rno03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    140583 (Chek1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Kdo APH
Other DBs
NCBI-GeneID: 140583
NCBI-ProteinID: NP_536325
RGD: 620545
Ensembl: ENSRNOG00000071217
UniProt: Q91ZN7 A6KRN1
Position
8:complement(44609417..44629867)
AA seq 476 aa
MAVPFVEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINK
MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY
LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLK
RKEFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
LLHKILVENPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDF
SPINSGSSEENVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPDHMLVNSQLL
GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTMDRR
NNKLIFKINLVEMDEKILVDFRLSKGDGLEFKRHFLKIKGKLSDIVSSQKVWFPVT
NT seq 1431 nt   +upstreamnt  +downstreamnt
atggcagtgccttttgtggaagactgggatttggtgcaaactttgggagaaggcgcctat
ggagaagttcaacttgctgtgaatagaataactgaagaagctgttgcagtgaaaattgta
gacatgaagcgggccatagactgcccagaaaatattaagaaagagatctgcatcaataag
atgttaaatcatgagaatgtagtgaaattctatggccacaggagggaaggcaacatccag
tacctgtttctggagtactgtagtggaggagaactctttgatagaatagagccagacata
gggatgcctgaacaagatgctcagaggtttttccatcagctcatggcgggggtggtttat
cttcatggcattggaataactcacagggatattaaaccagaaaacctcctcttggatgaa
agggataatctcaaaatctctgactttggcttggcaacagtgtttcggcataataatcgt
gagcgcttactgaacaagatgtgtgggactttaccttatgtcgctccagagcttctaaag
aggaaagaatttcacgcagaaccagttgatgtttggtcctgtggaatagtgcttactgca
atgttggctggagaattgccttgggaccagcccagtgatagctgtcaagaatattctgat
tggaaagaaaagaaaacctatctcaatccttggaaaaaaattgattctgctcctctggct
ttgcttcataaaattctagttgagaatccatcagcaaggatcaccatcccagacattaaa
aaagatagatggtacaacaaaccacttaacagaggagcgaagaggccacgtgctacttca
ggtggtatgtcagagtcttctagtggattctctaagcacattcattccaatttggacttt
tctccaataaatagtggttccagtgaagaaaacgtgaagttctctagttcccagccagag
cctcggacagggctttccttgtgggacactggcccctcaaatgtggacaaactggtgcaa
ggcatcagtttttcccagcctacgtgtcctgatcatatgcttgtaaacagtcagctactt
ggtacccctggatcttcacagaacccctggcagcgcttggtcaaaaggatgacacgattc
ttcactaaattggatgcagacaaatcttaccaatgcctgaaagagacctttgagaagttg
ggctatcagtggaagaagagttgtatgaatcaggttactgtatcaacaatggatagaaga
aacaataagttgattttcaaaataaatttggtagaaatggatgagaagatactggttgac
ttccggctttctaagggtgatgggttagagttcaagagacacttcctgaagattaaaggg
aagctcagcgatatcgtgagcagccagaaggtttggttccctgttacgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (15)   
   RefSeq(nuc) (7)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (50)   

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