KEGG   Rattus norvegicus (rat): 140928
Entry
140928            CDS       T01003                                 
Symbol
Pde11a
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform 4
  KO
K13298  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00230  Purine metabolism
rno01100  Metabolic pathways
rno04934  Cushing syndrome
rno05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    140928 (Pde11a)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    140928 (Pde11a)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    140928 (Pde11a)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     140928 (Pde11a)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     140928 (Pde11a)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 HD
Other DBs
NCBI-GeneID: 140928
NCBI-ProteinID: NP_543169
RGD: 621793
Ensembl: ENSRNOG00000024457
UniProt: Q8VID6
Position
3:complement(81320822..81704397)
AA seq 935 aa
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHSSGQGASDLRPALAGASS
LAQSSARGSTGIGGGAGPQGSANSHPASGGGESAGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSTTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVA
STGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSD
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGAYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAA
NRRKWEELHQKRLQVSAASPVPSSPSPAVAGEDRL
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcagcctcccgcctggacttcggggaggtggaaactttcctggataggcacccagaa
ttgtttgaagattacttgatgcgaaaaggaaagcaggagctggtggacaagtggctacaa
aggcacagttcgggacagggggcttcagacctgaggcctgccctggctggcgctagcagc
ttggctcagagcagtgccagaggcagcactggcataggtggtggtgctggaccccagggt
tctgccaacagtcatcccgcgtccggtggtggggaaagtgccggggttcctctgagtccc
agttgggccagtggcagccggggcgatggcaaccttcagaggagagcttcgcagaaagag
ctgagaaagagctttgcccgctccaaagccatccatgtgaacaggacctacgacgaacag
gtgacctcccgggcccaggagcccctgagcagtgtccggaggcgagccctgctcagaaag
gccagctctctgccccccaccacagcccacattctcagtgccctgctggaatcgagggtg
aatcttcctcagtatccccctacggccatcgactacaaatgccacctcaaaaagcataat
gagcgacagtttttcctggaactggtcaaggacatctccaatgaccttgacctcaccagc
ctaagctacaagatcctcatctttgtctgtctcatggtggacgctgaccgctgctctctc
ttcttagtggaaggggcagctgctggtaagaagactttggtctccaagttttttgacgtg
catgcaggaaccccactgctgccctgcagcaccacagagaactcaaatgaggtgcaggtc
ccctggggcaaaggtatcattggctatgtcggggaacacggagaaacagtcaacattccc
gatgcctaccaggaccgaagattcaatgatgaaattgacaagctgactggatacaagaca
aaatcactattgtgcatgcctatccggaacagtgacggtgagattatcggtgtggcccag
gcgataaataaggttcctgagggtgctccatttacagaagacgacgaaaaagttatgcag
atgtatcttccattctgtggcatcgccatatctaatgctcagctcttcgccgcctcgagg
aaagaatatgaaagaagtagggccttgctggaggtggtcaatgacctctttgaagaacag
actgacctggaaaagattgtcaagaaaataatgcatcgggcccaaactctgttgaaatgt
gaacgctgttccgttttacttctagaagacattgaatcaccagtggtgaagtttaccaaa
tcctttgaactgatgtccccaaagtgcagtgcggacgcggagaacagtttcaaagaaagt
gtggagaagtcatcttactccgactggctgataaataacagtatcgctgagctggttgct
tcgacaggccttcctgtgaatgtcagcgatgcctaccaggacccacgctttgacgctgag
gctgaccagatatctggctttcatataagatctgttctctgtgtccctatttggaacagc
aaccaccaaataataggggtcgctcaagtgctgaacagactcgatgggaaaccttttgat
gatgctgaccaaaggctttttgaggcctttgtcatcttttgtggccttggtattaacaac
acgattatgtacgaccaagtgaagaagtcctgggccaagcagtccgtggctcttgatgtg
ctgtcctaccacgccacgtgttccaaggctgaagttgacaagtttaaggcagccaacatc
cccctggtgtcggaactggccatcgatgacatccattttgatgacttttcccttgatgtt
gatgccatgatcacagccgctctacggatgttcatggagctggggatggtacagaaattt
aaaatcgactatgagaccctgtgcaggtggcttctgacagtaaggaaaaactatcggatg
gttctctaccacaactggagacatgccttcaacgtgtgccagctgatgtttgccatgcta
actactgctgggtttcaagagattctgaccgaggtggaaattttagcggtgattgtggga
tgcctgtgtcatgacctcgaccacaggggaaccaacaatgccttccaagctaagagtgac
tctgcactggcccagctctatgggacctcagcgaccttagagcatcaccactttaaccac
gccgtgatgatccttcagagtgagggtcacaacatctttgctaatttgtcctccaaggaa
tacagcgacctcatgcagctcctgaagcagtcgatactagccactgacctcacgctgtac
ttcgagagaagaactgagttcttcgagcttgtcagtaaaggagcctatgattggagcatc
acaagtcaccgcgatgtgtttcgatcaatgttaatgacagcttgtgaccttggagccgtg
accaaaccgtgggagatctccagacaggtggctgaacttgtcaccagcgagttcttcgaa
caaggagatcgggagaggtcggaactcaagctcaccccctctgctatttttgaccggaac
cggaaagatgagctgcctcggctgcaactggagtggattgacagcatctgcatgcctttg
tatcaggccttggtgaaagtcaatgcaaaactgaagccgatgctggactcagtggccgcc
aaccgcaggaagtgggaagagttgcaccaaaaaagactacaggtctctgctgcctcccca
gtcccttccagtcccagcccagcggtggccggagaggacagactgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (9)   
   RefSeq(nuc) (3)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (41)   

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