KEGG   Rattus norvegicus (rat): 161452
Entry
161452            CDS       T01003                                 
Symbol
Lef1
Name
(RefSeq) lymphoid enhancer-binding factor 1
  KO
K04492  lymphoid enhancer-binding factor 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04310  Wnt signaling pathway
rno04390  Hippo signaling pathway
rno04520  Adherens junction
rno04916  Melanogenesis
rno04934  Cushing syndrome
rno04936  Alcoholic liver disease
rno05132  Salmonella infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05200  Pathways in cancer
rno05210  Colorectal cancer
rno05213  Endometrial cancer
rno05215  Prostate cancer
rno05216  Thyroid cancer
rno05217  Basal cell carcinoma
rno05221  Acute myeloid leukemia
rno05224  Breast cancer
rno05225  Hepatocellular carcinoma
rno05226  Gastric cancer
rno05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    161452 (Lef1)
   04390 Hippo signaling pathway
    161452 (Lef1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    161452 (Lef1)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    161452 (Lef1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    161452 (Lef1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    161452 (Lef1)
   05225 Hepatocellular carcinoma
    161452 (Lef1)
   05226 Gastric cancer
    161452 (Lef1)
   05216 Thyroid cancer
    161452 (Lef1)
   05221 Acute myeloid leukemia
    161452 (Lef1)
   05217 Basal cell carcinoma
    161452 (Lef1)
   05215 Prostate cancer
    161452 (Lef1)
   05213 Endometrial cancer
    161452 (Lef1)
   05224 Breast cancer
    161452 (Lef1)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    161452 (Lef1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    161452 (Lef1)
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    161452 (Lef1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    161452 (Lef1)
   04934 Cushing syndrome
    161452 (Lef1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rno03000]
    161452 (Lef1)
Transcription factors [BR:rno03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    161452 (Lef1)
SSDB
Motif
Pfam: CTNNB1_binding HMG_box HMG_box_2
Other DBs
NCBI-GeneID: 161452
NCBI-ProteinID: NP_569113
RGD: 620241
Ensembl: ENSRNOG00000010121
UniProt: Q9QXN1
Position
2:222340541..222453931
AA seq 397 aa
MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESE
IIPASNGHEVVRQTQSSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNS
DPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSEVNPKQ
GMSRHPPAPEMPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQAYPSSLSGDTSMSRF
SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKP
LNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
YPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI
NT seq 1194 nt   +upstreamnt  +downstreamnt
atgccccaactttccggaggaggcggtgggggggacccggaactctgcgccaccgatgag
atgatccccttcaaggacgagggcgatccccagaaggagaagattttcgccgagatcagt
caccccgaagaggagggcgacttagcagacatcaagtcatccttggtaaacgagtccgaa
atcatcccagccagcaacgggcatgaggtggtcagacaaacacagtcctctcaggagccc
taccacgacaaggccagagagcacccggatgacggaaagcatccggacggaggtctatat
aacaagggcccctcctactccagttactctggctacatcatgatgcccaatatgaatagc
gacccatacatgtcaaatggatccctttctccacccatcccgaggacctcaaataaagtg
ccggtggtgcagccatctcacgcggtccaccccctcacgcccctcatcacgtacagcgac
gagcacttttctccaggatctcacccgtcacacatcccgtcagaggtcaaccccaagcaa
ggcatgtccagacaccctccagctcctgaaatgcccaccttctaccccctgtctccaggc
ggcgttggacagatcaccccacccctcggctggcaaggtcagcctgtttatcccatcacg
ggtggattcaggcaagcctacccatcctcactgtcaggcgacacttccatgtccaggttt
tcccatcacatgattcctggtccccctggcccccacacaactggcatccctcatccagca
attgtaacacctcaggtcaaacaggagcacccccacacggacagcgacctaatgcacgtg
aagcctcagcacgaacagagaaaggaacaggagcctaaaagacctcatattaagaagcct
ctgaatgctttcatgttatacatgaaagaaatgagggcgaatgtcgtagccgagtgtacg
ctaaaggagagcgcagctatcaaccagatcctgggcagaaggtggcacgccctctcccgg
gaagagcaggccaaatattatgaattagcgcggaaagaaagacagctacatatgcagctc
tatccaggctggtcagcgagagacaattatggcaagaagaagaagaggaagagagagaag
ctacaggaatctacttcaggtacaggtcccagaatgacagctgcctacatctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (19)   
   KEGG PATHWAY (19)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (15)   
   RefSeq(nuc) (11)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (59)   

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