KEGG   Rattus norvegicus (rat): 170921
Entry
170921            CDS       T01003                                 
Symbol
Itga2
Name
(RefSeq) integrin alpha-2 precursor
  KO
K06481  integrin alpha 2
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03271  Virion - Rotavirus
rno04145  Phagosome
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04611  Platelet activation
rno04640  Hematopoietic cell lineage
rno04810  Regulation of actin cytoskeleton
rno04820  Cytoskeleton in muscle cells
rno05165  Human papillomavirus infection
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05222  Small cell lung cancer
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03271 Virion - Rotavirus
    170921 (Itga2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    170921 (Itga2)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    170921 (Itga2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    170921 (Itga2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    170921 (Itga2)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    170921 (Itga2)
   04810 Regulation of actin cytoskeleton
    170921 (Itga2)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    170921 (Itga2)
   04611 Platelet activation
    170921 (Itga2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    170921 (Itga2)
   05205 Proteoglycans in cancer
    170921 (Itga2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    170921 (Itga2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    170921 (Itga2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    170921 (Itga2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    170921 (Itga2)
   05414 Dilated cardiomyopathy
    170921 (Itga2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    170921 (Itga2)
   04515 Cell adhesion molecules [BR:rno04515]
    170921 (Itga2)
   04090 CD molecules [BR:rno04090]
    170921 (Itga2)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   170921 (Itga2)
  Exosomal proteins of bladder cancer cells
   170921 (Itga2)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   170921 (Itga2)
CD molecules [BR:rno04090]
 Proteins
  170921 (Itga2)
SSDB
Motif
Pfam: VWA Integrin_A_Ig_2 Integrin_A_Ig_3 FG-GAP VWA_2 FG-GAP_2 FG-GAP_3 Integrin_alpha DUF11 ITGAX-like_Ig_3 HisK_sensor
Other DBs
NCBI-GeneID: 170921
NCBI-ProteinID: NP_001414220
RGD: 621632
Ensembl: ENSRNOG00000058111
Position
2:complement(48253412..48354509)
AA seq 1178 aa
MGPGQAGGALLLQLLLLTQGLLSCLAYNVGLPGAKIFSGSSSEQFGYSVQQLTTPQGNWL
LVGSPWSGFPDNRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNP
GTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQSLTSFSPAVQACPSLVDVVVVCDESN
SIYPWEAVKNFLEKFVQGLDIGPKKTQVALIQYANDPRVVFNLTTYKNKEDMVQATSETR
QYGGDLTNTFKAIQFARDIAYLPESGGRPGATKVMVVVTDGESHDGSKLQTVIQQCNDDE
ILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEHIFS
IEGTVQGGDNFQMEMAQVGFSADYSPQNDILMLGAVGAFDWSGTVVQETSYEHLIFPKQA
FDQVLQDRNHSSFLGYSVAAISTENGVHFVAGAPRANYTGQIVLYSVNKHGNVTVIQSHR
GDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMNDLKKEEGKVYLFTITKGVLNQHQFL
EGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQK
ILGSDGAFKSHLQFFGRSLDGYGDLNGDSITDVSIGALGQVVQLWSQSVADVATEASFTP
DKIILLNKEAKITLKLCFRAKFRPPGQNHQVAILFNMTLDADQYSSRVTSRGIFRENSER
FLQKTMVVSEVENCSEYHISIQKPSDVVNPLDLRVDISLEKPGTSPALEAYSETVKVFSI
PFYKECGSDGICISDLILDVRQLPALRNQPFIVSNQNKRLTFSVTLKNRGESAYNTAVLA
EFSENLFFASFSMPVDGTEVTCQIGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQ
NQAAINFQAFSESQETNKADNSVSLIVPLLYDAELHLTRSTNINFYEISSDENAPSVINS
VEDIGPEFIFSLKITAGSAPVSMASVTIHIPLHTKEKNPLLYLTGIQTDKAGDISCRAEI
NPLNLPHTASPVSFKSENFRHMKELDCKTTSCSNVSCWLKDLHMKAEYFINVTTRVWNRT
FAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGI
LLLLAMVAGLWKLGFFKRQYKKMGQNPDETDETTELNS
NT seq 3537 nt   +upstreamnt  +downstreamnt
atgggaccgggacaggcagggggcgcgcttctgctgcagctgctactgctcactcaaggt
cttttgagttgtctggcatataatgttggcctcccaggagcgaaaatattttctgggtct
tcaagtgaacagtttggctattcggtgcagcagcttacgaccccacaaggcaactggcta
ctggttggttcgccatggagtggcttccctgacaaccgaatgggagacgtgtacaagtgc
cctgttgacttacccactgccacctgtgaaaagctgaatctgcaaaattcagcaagcatc
tcaaatgttaccgagataaagaccaacatgagcctgggtttgaccctcaccaggaatccg
gggaccggcggctttctaacctgcggtcctctgtgggcacatcagtgtggaaatcagtat
tatgcaactggaatttgttctgatgtcagtccagactttcagtcgttgacaagcttctca
cctgcagttcaagcttgcccttccctcgtagatgtcgtagttgtctgtgatgaatcaaac
agtatttatccctgggaagcagtaaagaattttttggaaaagtttgtgcaaggcctggat
ataggacctaaaaagacacaggtggcgttaattcaatatgccaacgacccaagagttgtc
tttaacttgaccacttacaaaaacaaagaagatatggttcaggccacatccgagacgcgc
cagtatggtggggacctcacaaacaccttcaaggctatccaatttgcaagagacattgct
tatttaccggagtctggcgggcgcccaggtgctacaaaagtcatggtagttgtgactgat
ggggaatcccatgatgggtcgaagctgcaaactgtgatccagcaatgcaatgatgacgag
atactgaggtttggcatagcggttcttggatatttaaacagaaatgctcttgatactaaa
aatctaatcaaagaaattaaagcaatcgctagcactccaacggagaggtactttttcaat
gtggccgatgaggcggctcttctggagaaagctggcactctaggggagcacatattcagc
attgaaggcactgttcaaggaggagacaacttccagatggaaatggcacaagttggattc
agtgcagattactctcctcaaaatgatatcctgatgctaggtgcagtgggagcttttgac
tggagtggaactgttgtccaggagacatcttacgagcacttgatctttcctaaacaagcc
tttgaccaggttctgcaggatagaaatcacagttcatttttaggttactctgtggctgca
atttctactgaaaatggtgtccactttgttgctggtgctcctcgagcaaattatactggc
cagatagtgctgtacagtgttaacaagcatggcaatgtgaccgtgattcagtctcacaga
ggggaccagattggctcctattttggcagtgtgctgtgttcggtggatgtggataaagat
accattacagatgtgctcttggtaggtgctcccatgtacatgaacgacctcaagaaagaa
gaagggaaagtctacctgttcacaatcacaaagggcgtcctgaaccagcaccagtttctt
gaaggacctgaaggcactggaaatgctcggtttggttcagcaattgcagccctttcagac
atcaacatggatggctttaatgatgtgattgttggttcgcctgtagagaatgagaactct
ggagctgtgtacatctacaatggccaccagggtaccattcgcaccaagtactcccagaaa
atccttggatccgacggagcctttaagagccatctccagttctttggaaggtccctggat
ggctatggagatttaaatggggactccatcactgatgtatccattggtgctttggggcaa
gtggttcaactctggtcacaaagcgttgcagatgtggccacagaagcttcgttcactcca
gacaaaatcatattgctcaacaaggaagctaagataaccctcaaactctgcttcagagca
aagtttagacctcctgggcaaaaccaccaagtggccatcctgtttaacatgacacttgat
gctgaccaatattcatccagagtaacctccagggggatatttagagaaaatagtgagcga
ttcttgcagaagactatggttgtaagtgaagtggagaactgttctgagtaccacattagt
atacagaagccctctgatgttgtcaaccctttggatctgcgagtggacatcagtttggaa
aagccaggcactagccctgcccttgaagcctattcagaaactgtgaaagtcttcagtatc
cctttctataaagagtgtggcagcgatggaatttgcatctctgacctgatcctggatgtc
cgacagctgccagcccttagaaatcagccctttattgtcagtaaccaaaacaagaggtta
acattttcagtcacactgaaaaacagaggggaaagcgcgtacaacactgccgtcctggct
gagttttctgagaacttgttttttgcctctttctccatgccggtcgatggaacagaagta
acatgccagattggttcatcacagaaatctgttacctgtgacgtgggataccctgcctta
aagagtgagcagcaggtgacttttaccattaacttcgacttcaatcttcagaacctccag
aatcaggcggccatcaatttccaagccttcagtgagagccaagaaacaaacaaagcagac
aattcggtcagcctcatagttcctctcctgtatgacgctgaacttcacttaaccagatcc
accaacataaacttttatgaaatctcttcggatgagaatgctccttctgtcataaacagt
gttgaagatattggtcctgaattcatcttctctctcaagataacagcgggaagtgctcca
gtgagcatggcatcagtaaccatccacattcctctgcacaccaaggaaaagaacccactc
ctgtatctgaccgggatacaaacagacaaggctggcgacatcagctgcagagcagaaatt
aatccactaaacttaccacacacggcctcacccgtatctttcaagagtgaaaacttccgg
catatgaaagaattggactgcaaaaccacttcctgcagtaacgtctcctgctggctgaaa
gaccttcacatgaaagcggagtactttatcaatgtgactaccagggtttggaacaggacc
tttgctgcatcaactttccagactgtgcagctgacagcagcagccgagatcgatacgcat
aaccctcagctcttcgtgattgaagaaaatgctgtcacgattcccctcatgataatgaaa
cccaccgagaaagcagaagtgcccacaggagttatcataggaagcataattgctggaatc
cttttgctgttggctatggttgcaggcttgtggaagctcggcttcttcaaaagacaatat
aaaaaaatgggccaaaatccagatgagacggacgagaccacagaactcaacagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (11)   
   Pfam (11)   
All databases (43)   

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