KEGG   Rattus norvegicus (rat): 171009
Entry
171009            CDS       T01003                                 
Symbol
Actn3
Name
(RefSeq) alpha-actinin-3
  KO
K21073  actinin alpha 2/3
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04820  Cytoskeleton in muscle cells
rno05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    171009 (Actn3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    171009 (Actn3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    171009 (Actn3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:rno04812]
    171009 (Actn3)
   04147 Exosome [BR:rno04147]
    171009 (Actn3)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    171009 (Actn3)
Cytoskeleton proteins [BR:rno04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     171009 (Actn3)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   171009 (Actn3)
  Exosomal proteins of colorectal cancer cells
   171009 (Actn3)
  Exosomal proteins of bladder cancer cells
   171009 (Actn3)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_7 EF-hand_1 EF-hand_6 CAMSAP_CH EF-hand_8 AIF-1 PRP9_N
Other DBs
NCBI-GeneID: 171009
NCBI-ProteinID: NP_596915
RGD: 621792
Ensembl: ENSRNOG00000019745
UniProt: F7FM00 Q8R4I6
Position
1:complement(211588473..211604401)
AA seq 900 aa
MMMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRK
AGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKL
VSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQ
NFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDI
VNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELL
EWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRL
SHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHE
AWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYH
EAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDG
AIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPK
SGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQ
GKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQEGLVFDNKHTV
YSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMME
PDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVAS
FKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL
NT seq 2703 nt   +upstreamnt  +downstreamnt
atgatgatggttatgcagcccgagggtctgggggccggggaggggcccttctctggtggc
gggggcggtgagtacatggaacaggaggaagactgggaccgcgacttgctgttggatcct
gcctgggagaaacagcagcggaaaaccttcactgcatggtgcaactcccatctgcgcaag
gcaggcacacagatcgagaacattgaagaggacttccgcaatggcctgaagctcatgctg
ctcctggaggtcatttctggagagaggctgcccaggccagacaaaggcaagatgcgcttc
cacaaaatcgccaatgtcaacaaagccctggacttcattgccagcaaaggagttaagcta
gtgtccatcggtgctgaagaaattgttgacgggaacctgaagatgaccctgggcatgatc
tggaccatcatcctccgctttgccattcaggacatctctgtagaagagacctcagccaaa
gaaggcttgcttctctggtgtcagcggaaaacagcaccataccgcaatgtcaacgtacag
aacttccataccagctggaaggatggcctggccctctgtgctctcatccaccgccaccgg
ccagatctcattgactatgccaagcttcgcaaggatgaccccattggaaacctgaacact
gcctttgaggtggcagagaaatacctggacatccctaagatgctggatgcagaagatatt
gtgaacacccccaaaccagatgagaaagccatcatgacctatgtttcctgcttctaccat
gcatttgctggggctgagcaggcagagactgctgccaacaggatctgcaaggtcttagct
gtgaaccaggaaaacgagaagctgatggaggagtatgagaaactggctagtgagctgttg
gagtggatccgccgcactgtcccatggctagagaaccgagtgggtgaacccagcatgagt
gccatgcagcgcaagctggaggacttccgcgactacaggcgcctgcacaagcctccccgt
gtgcaggagaagtgccagctggagatcaacttcaacacgctgcagaccaagctgcgcctg
agccaccgacctgctttcatgccctcagagggcaagctggtttcggacatagccaatgcg
tggcggggactggagcaggtggagaagggctatgaggactggctgctttcagagatcagg
cgtctgcagaggcttcagcacctggctgagaagttccagcagaaggcttccctgcatgaa
gcttggacccggggcaaagaggaaatgttaaaccagcatgactacgagtcagcttcgctg
caggaggtgcgtgcgctcttgcgacgtcatgaggcctttgagagcgacttggctgcacat
caagaccgggtggaacacattgcagccctggcccaggaactcaatgagctggactaccat
gaggcagcctcggtgaatagccgctgccaagccatctgcgaccagtgggataacttgggt
acactgacccagaagaggagggatgcactagagagaatggagaagctcctggaaaccatt
gaccagctgcagctggagtttgctcggcgggcagcgcccttcaacaactggctggatggg
gctattgaggacctgcaggatgtgtggctagtgcactctgtagaagagacgcagagcctg
ctaacagcacatgaacagttcaaggcaacgttgcctgaggcggatcgagagcgaggtgcc
atcctgggcattcaaggagagattcagaagatctgtcagacgtatggactgcggccaaag
tctggcaacccctacatcaccctcagctcgcaggacatcaacaataagtgggacacggtc
agaaagctggtacccagccgtgaccagacactgcaggaggagctggcccggcagcaggtg
aatgagaggctccggcgacagtttgcagcccaggccaatgccataggaccctggatccag
ggaaaggtggaggaagtagggcggctggcagctgggctggctggctctctggaggagcag
atggcaggtctgcgacagcaggagcagaacatcatcaattacaagagcaacatcgaccgg
ctggagggtgaccaccagctgctgcaggagggcctagtctttgacaacaagcacacggtc
tacagcatggagcacatccgtgtgggctgggagcagctgctcacctccattgcccgcacc
atcaatgaggtggagaaccaggtactgacccgagatgccaagggcctgagccaggaacag
ctcaacgagttccgggcatctttcaaccactttgaccggaagcggaatgggatgatggaa
cctgatgatttccgagcttgcctcatctccatgggctatgatctgggagaggtggagttt
gctcggatcatgaccatggtggaccccaatgcagctggggtcgtgaccttccaagccttc
attgacttcatgacccgagagactgcagagacagacacagctgaacaagttgtagcctcc
ttcaaaatcctagcaggagacaagaactacattaccccagaagagctgcggagggagctc
ccagccgagcaggctgagtactgcatccgtcggatggcaccctacaaaggatcgggggct
ccgtccggggccctggactacgtggctttctctagtgccctctacggagagagtgacctc
tga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (10)   
   Pfam (10)   
All databases (33)   

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