KEGG   Rattus norvegicus (rat): 171341
Entry
171341            CDS       T01003                                 
Symbol
Mgst1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    171341 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    171341 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    171341 (Mgst1)
   00983 Drug metabolism - other enzymes
    171341 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    171341 (Mgst1)
   05204 Chemical carcinogenesis - DNA adducts
    171341 (Mgst1)
   05207 Chemical carcinogenesis - receptor activation
    171341 (Mgst1)
   05208 Chemical carcinogenesis - reactive oxygen species
    171341 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    171341 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    171341 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    171341 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    171341 (Mgst1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     171341 (Mgst1)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   171341 (Mgst1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 171341
NCBI-ProteinID: NP_599176
RGD: 70927
Ensembl: ENSRNOG00000007743
UniProt: P08011 B6DYQ4
Structure
Position
4:172760930..172776157
AA seq 155 aa
MADLKQLMDNEVLMAFTSYATIILAKMMFLSSATAFQRLTNKVFANPEDCAGFGKGENAK
KFLRTDEKVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALIHFRIFVGARIYHTIA
YLTPLPQPNRGLAFFVGYGVTLSMAYRLLRSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggctgacctcaagcagctcatggacaacgaggtgttgatggcctttacctcctatgca
acgatcattcttgccaagatgatgttcctgagctccgcgactgcattccagaggctaacc
aacaaggtttttgccaacccggaagactgtgctggcttcggcaagggggagaatgccaag
aagttccttcggactgacgagaaggtggaacgcgtgcgaagagcccacctgaacgacctt
gaaaacatcgttccctttctcggtatcggcctcctgtactccctgagcggaccggatctc
tctacagccctcattcacttcagaatctttgtgggcgctcggatctaccacaccattgct
tacttgactccccttcctcagccaaacaggggcttggcattttttgttggctacggagtt
actttgtcaatggcttacaggctgctcaggagcagactgtacttgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (41)   
   RefSeq(nuc) (1)   
   GenBank (20)   
   EMBL (20)   
3D Structure (3)   
   PDB (3)   
Protein domain (1)   
   Pfam (1)   
All databases (139)   

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