KEGG   Rattus norvegicus (rat): 192262
Entry
192262            CDS       T01003                                 
Symbol
C1s
Name
(RefSeq) complement C1s subcomponent precursor
  KO
K01331  complement component 1, s subcomponent [EC:3.4.21.42]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04610  Complement and coagulation cascades
rno05133  Pertussis
rno05150  Staphylococcus aureus infection
rno05171  Coronavirus disease - COVID-19
rno05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    192262 (C1s)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    192262 (C1s)
  09171 Infectious disease: bacterial
   05133 Pertussis
    192262 (C1s)
   05150 Staphylococcus aureus infection
    192262 (C1s)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    192262 (C1s)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    192262 (C1s)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    192262 (C1s)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.42  complement subcomponent C_overbar_1s_
     192262 (C1s)
Peptidases and inhibitors [BR:rno01002]
 Serine peptidases
  Family S1: chymotrypsin family
   192262 (C1s)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Opsonins
    192262 (C1s)
SSDB
Motif
Pfam: Trypsin CUB Sushi FXa_inhibition EGF_CA HRM CUB_2 Trypsin_2 EGF hEGF
Other DBs
NCBI-GeneID: 192262
NCBI-ProteinID: NP_620255
RGD: 619983
Ensembl: ENSRNOG00000011971
UniProt: Q6P6T1
Position
4:complement(159116549..159128736)
AA seq 694 aa
MGKSPEMWCFVFFSLLASFSAEPTMYGEILSPNYPQAYPNEVVKTWDIEVPEGFGIHLYF
THLDMELSENCAYDSVQIISGGIEEERLCGQRTSKSPNSPIVEEFQFPYNRLQVVFTSDF
SNEERFTGFAAYYSAVDVNECTDFTDVPCSHFCNNFIGGYFCSCPPEYFLHDDMRTCGVN
CSGDVFTALIGEIASPNYPNPYPENSRCEYQIRLQEGFRLVLTIRREDFDVEPADSEGNC
HDSLTFAAKNQQFGPYCGNGFPGPLTIKTQSNTLDIVFQTDLTGQNKGWKLRYHGDPIPC
PKEISANSIWEPEKAKYVFKDVVKITCVDGFEVVEGNVGSTSFYSTCQSNGQWSNSRLEC
QPVDCGVPEPIENGKVEDPEDTVFGSVIHYTCEEPYYYMEQEEGGEYHCAANGSWVNDQL
GVELPKCIPVCGVPTEPFKVQQRIFGGYSTKIQSFPWQVYFESPRGGGALIDEYWVLTAA
HVVEGNSDPVMYVGSTLLKIERLRNAQRLITERVIIHPSWKQEDDLNTRTNFDNDIALVQ
LKDPVKMGPTVAPICLPETSSDYNPSEGDLGLISGWGRTENRTNVIQLRGAKLPITSLEK
CQQVKVENPKARSNDYVFTDNMICAGEKGVDSCEGDSGGAFALPVPNVKDPKFYVAGLVS
WGKKCGTYGIYTKVKNYVDWILKTMQENSGPKKD
NT seq 2085 nt   +upstreamnt  +downstreamnt
atgggcaaatcgccagagatgtggtgctttgtcttcttttctcttttggcatcgttttct
gctgagcctaccatgtatggggagatcctgtcccctaattatccccaggcgtaccccaat
gaggtcgtgaaaacttgggacatagaagtcccagaggggtttgggattcacctttacttc
acccatctggacatggagctgtcagagaactgtgcatacgactcagtgcagataatctca
ggaggcatcgaggaagagagactctgtggccagaggaccagcaagagtcccaactccccc
attgtagaagagtttcaattcccatacaataggctccaggtggtctttacgtcagacttc
tccaacgaggaacggtttactggctttgcagcgtattactcagccgtagatgtaaatgaa
tgcacagactttacagatgtcccttgcagccacttctgcaataacttcattggtggatac
ttctgctcctgccccccagaatacttcctccacgatgacatgaggacttgtggggtcaac
tgtagtggggatgtattcactgccctgattggggagatcgcaagtcccaattatcccaac
ccatacccggagaactcaaggtgtgaataccagattcggctgcaggagggcttccgactg
gtgttgactatccggagagaagattttgatgtggaaccagctgactcagaggggaactgc
cacgacagtttgacttttgctgcaaaaaaccaacagtttggtccttactgtggcaatgga
ttccctggaccgctaactattaaaacccagagcaatactcttgatattgtctttcaaact
gacctaacggggcaaaataaaggctggaagcttcgttaccatggggatcccatcccctgt
cccaaagaaatcagtgctaattctatctgggagcccgaaaaggcaaaatacgtgttcaaa
gatgtcgtgaagataacctgtgtggatggattcgaagttgtggagggaaatgttggctca
acatcattctattccacttgtcaaagcaacggacagtggagcaattccaggctagagtgt
caacctgtggactgtggtgttccagaacccattgagaatggtaaagttgaagacccagaa
gacactgtattcggctccgtcatccactacacgtgcgaagagccatattactacatggaa
caggaagaaggcggagagtatcactgcgctgctaatgggagctgggtgaatgaccagctg
ggtgtcgagcttccaaaatgtattccagtctgtggagtacccaccgagccctttaaagta
cagcagaggatatttggaggatactctacaaagattcaaagttttccttggcaggtctac
tttgagtccccccgaggtggcggggctcttatcgatgagtactgggtgctgacggccgct
cacgttgtggagggaaactctgacccagtgatgtatgtcgggtccacacttctgaaaata
gagcggttgagaaatgcccagaggctcatcactgaacgtgtgattattcatcccagctgg
aaacaagaggacgacctgaatacacggacaaattttgacaatgacattgccctggtgcag
ctcaaagaccctgtgaaaatgggacccactgttgcccccatctgcctgccagaaacctcc
tcagactacaacccctcagagggtgacctggggctgatctctgggtggggccgaacagag
aatagaaccaatgttattcaactcagaggggcgaagttacccataacatctttagaaaag
tgccagcaggtgaaagtggaaaacccgaaagcgaggtcaaacgactatgttttcactgac
aacatgatctgtgctggggaaaagggtgtggacagctgtgagggtgacagcggaggggct
tttgctctgccggtccccaatgtcaaggaccccaaattctatgtggctggcctggtgtcc
tgggggaaaaagtgtgggacctatgggatctacacaaaggtaaagaactacgtggactgg
atcctgaaaactatgcaggagaatagtgggcccaagaaggactga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (10)   
   Pfam (10)   
All databases (35)   

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