KEGG   Rattus norvegicus (rat): 192268
Entry
192268            CDS       T01003                                 
Symbol
Gls2
Name
(RefSeq) glutaminase liver isoform, mitochondrial isoform 1
  KO
K01425  glutaminase [EC:3.5.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00220  Arginine biosynthesis
rno00250  Alanine, aspartate and glutamate metabolism
rno00470  D-Amino acid metabolism
rno01100  Metabolic pathways
rno04724  Glutamatergic synapse
rno04727  GABAergic synapse
rno04964  Proximal tubule bicarbonate reclamation
rno05206  MicroRNAs in cancer
rno05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    192268 (Gls2)
   00220 Arginine biosynthesis
    192268 (Gls2)
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    192268 (Gls2)
 09150 Organismal Systems
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    192268 (Gls2)
  09156 Nervous system
   04724 Glutamatergic synapse
    192268 (Gls2)
   04727 GABAergic synapse
    192268 (Gls2)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    192268 (Gls2)
   05230 Central carbon metabolism in cancer
    192268 (Gls2)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.2  glutaminase
     192268 (Gls2)
SSDB
Motif
Pfam: Glutaminase EF-hand_14 Ank_4 Ank_2 Ank Ank_5 Ank_3
Other DBs
NCBI-GeneID: 192268
NCBI-ProteinID: NP_001257715
RGD: 620359
Ensembl: ENSRNOG00000031612
UniProt: P28492
Position
7:1201757..1218014
AA seq 602 aa
MRSMRALQNALSRAGSHGQRGGWGHPSRGPLLGGGVRYYFGEAAAQGRGTPHSHQPQHSD
HDASNSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQ
ESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKELTGGKVA
AYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHK
FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG
NEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESG
SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA
ILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGG
EVRNKTVVNLLFAAYSGDVSALRRFALSAVDMEQKDYDSRTALHVAAAEGHIDVVKFLIE
ACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSYMLSETQAEVAAETLSKENLES
MV
NT seq 1809 nt   +upstreamnt  +downstreamnt
atgcgctccatgagggctctgcagaacgcgctgagccgcgcgggcagccacggccagagg
ggaggctggggtcacccgagccggggcccgctcctgggcgggggtgtccggtactacttc
ggtgaggccgcggcgcagggcagggggacgccgcacagccaccagccgcagcactcggac
catgatgcctcgaacagtggcatgttgcctcgacttggtgacctgcttttctacaccatt
gcagaggggcaggaacgcatccccatccataagttcaccacggccctgaaggccactgga
ctgcagacgtcagacccacggctccaggactgcatgagcaagatgcagcgcatggtccaa
gagtccagcagtggtggcctcttggaccgagaactcttccaaaagtgtgtgagcagcaac
attgtgctcctgactcaggcattccggaagaagtttgtcattcctgactttgaggagttc
acaggccatgtggatcgtatatttgaggatgccaaagagctcactggaggcaaagtggca
gcctacatccctcacctggccaagtcaaacccagatctttggggcgtctccctgtgcact
gtggatgggcagcgacactctgtgggccacacgaagatccctttctgcctacagtcctgt
gtcaagccactcacttacgccatctccgtgagcaccttaggcaccgactacgtgcacaag
ttcgtgggcaaggaacccagtggtctgcgctataacaaactctccctcaacgaggaagga
atccctcataaccccatggtcaatgctggtgctattgtggtcagctccctgatcaagatg
gactgtaacaaagcagagaagtttgactttgtgttacagtatctgaacaagatggctggg
aatgaattcatggggttcagcaatgccacattccagtcagagaaggagactggggatcgg
aattacgccattggctattacctcaaggagaagaagtgcttccctaagggagtggacatg
atggctgcccttgatctctatttccagctgtgctctgtggaggttacctgtgagtcaggc
agtgtcatggcggccactcttgccaatggcggcatctgccccatcacaggggagagcgtg
ctgagtgcggaagccgtgcgcaacaccctcagcctcatgcactcctgtggcatgtatgac
ttctcgggccagtttgccttccacgtgggcctgccagccaagtcagctgtgtcgggagcc
atcctcctggttgtacccaatgtcatggggatgatgtgtctgtcacccccgttagacaag
ctggggaacagccacaggggcatcagcttctgccagaagttggtgtctctgtttaacttc
cacaactacgacaacctgcggcactgtgctcggaagttagacccacggagggaagggggg
gaagttcggaacaagaccgtggtgaacctgttatttgctgcatatagtggagatgtctca
gctcttcgaaggtttgccttgtctgccgtggatatggagcagaaggactatgattcccgc
acagccctacatgtggcggcagcggaaggacacattgacgttgtcaagtttctgatcgag
gcttgcaaagtgaatccttttgtcaaggacaggtggggcaacattcccctggatgatgcc
gtgcagttcaatcacctggaggtggtcaaactgcttcaggattaccatgactcctacatg
ctgtctgagactcaagctgaggtagcagctgagactctgtcaaaagagaacttagagagc
atggtgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (29)   
   RefSeq(nuc) (9)   
   GenBank (10)   
   EMBL (10)   
Protein domain (7)   
   Pfam (7)   
All databases (74)   

Download RDF
DBGET integrated database retrieval system