KEGG   Rattus norvegicus (rat): 24310
Entry
24310             CDS       T01003                                 
Symbol
Ace
Name
(RefSeq) angiotensin-converting enzyme precursor
  KO
K01283  peptidyl-dipeptidase A [EC:3.4.15.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04614  Renin-angiotensin system
rno04924  Renin secretion
rno05142  Chagas disease
rno05171  Coronavirus disease - COVID-19
rno05410  Hypertrophic cardiomyopathy
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    24310 (Ace)
   04614 Renin-angiotensin system
    24310 (Ace)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    24310 (Ace)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    24310 (Ace)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    24310 (Ace)
   05415 Diabetic cardiomyopathy
    24310 (Ace)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    24310 (Ace)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    24310 (Ace)
   04090 CD molecules [BR:rno04090]
    24310 (Ace)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.15  Peptidyl-dipeptidases
    3.4.15.1  peptidyl-dipeptidase A
     24310 (Ace)
Peptidases and inhibitors [BR:rno01002]
 Metallo peptidases
  Family M2
   24310 (Ace)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   24310 (Ace)
CD molecules [BR:rno04090]
 Proteins
  24310 (Ace)
SSDB
Motif
Pfam: Peptidase_M2 Peptidase_M32 DUF713
Other DBs
NCBI-GeneID: 24310
NCBI-ProteinID: NP_036676
RGD: 2493
Ensembl: ENSRNOG00000062101
Vega: OTTRNOG00000002214
UniProt: P47820
Position
10:91410129..91430246
AA seq 1313 aa
MGAASGQRGRWPLSPPLLMLSLLLLLLLPPSPAPALDPGLQPGNFSADEAGAQLFADSYN
SSAEVVMFQSTAASWAHDTNITEENARLQEEAALINQEFAEVWGKKAKELYESIWQNFTD
QKLRRIIGSVQTLGPANLPLTQRLQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTN
ILASSRNYAKVLFAWEGWHDAVGIPLKPLYQDFTALSNEAYRQDGFSDTGAYWRSWYESP
SFEESLEHLYHQVEPLYLNLHAFVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWENIY
DMVVPFPDKPNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLSPMPPEFWAESMLEKPADG
REVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHVQYYLQYKDLHVSLRRGANP
GFHEAIGDVLALSVSTPAHLHKIGLLDRVANDIESDINYLLKMALEKIAFLPFGYLVDQW
RWGVFSGRTPPSRYNYDWWYLRTKYQGICPPVARNETHFDAGAKFHIPSVTPYIRYFVSF
VLQFQFHQALCKEAGHQGPLHQCDIYQSTKAGAKLQQVLQAGCSRPWQEVLKDLVGSDAL
DASALMEYFQPVSQWLQEQNQRNGEVLGWPEYQWRPPLPDNYPEGIDLETDEAKANRFVE
EYDRTAKVLWNEYAEANWHYNTNITIEGSKILLQKNKEVSNHTLKYGTWAKTFDVSNFQN
STIKRIIKKVQNVDRAVLPPNELEEYNQILLDMETTYSVANVCYTNGTCLSLEPDLTNIM
ATSRKYEELLWVWKSWRDKVGRAILPFFPKYVDFSNKIAKLNGYSDAGDSWRSSYESDDL
EQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDL
VAPFPSAPSIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGRE
VVCHASAWDFYNGKDFRIKQCTSVNMEELVIAHHEMGHIQYFMQYKDLPVTFREGANPGF
HEAIGDVLALSVSTPKHLHSLNLLSSEGSGYEHDINFLMKMALDKIAFIPFSYLIDQWRW
RVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYIRYFISFII
QFQFHEALCRAAGHTGPLYKCDIYQSKEAGKLLADAMKLGYSKQWPEAMKIITGQPNMSA
SAIMNYFKPLTEWLVTENRRHGETLGWPEYTWTPNTARAEGSLPESSRVNFLGMYLEPQQ
ARVGQWVLLFLGVALLVATVGLAHRLYNIHNHHSLRRPHRGPQFGSEVELRHS
NT seq 3942 nt   +upstreamnt  +downstreamnt
atgggggccgcgtccggccagcgggggcggtggccgttgtcaccgccgctcttgatgctg
tcgctgctgctgctgctgctgctgccgccgtcgcccgccccggcgcttgaccctggattg
cagccgggcaacttttccgcggacgaggcaggggcgcagctcttcgctgacagctataac
tcgagtgccgaggtggtgatgttccagagcaccgcagccagctgggcgcacgacaccaac
atcacggaggagaatgcgcggctccaggaggaagcggccctgatcaaccaggagtttgca
gaggtctggggcaagaaggccaaggagctgtatgagtccatctggcagaacttcactgac
caaaagctgcgaaggatcatcggatccgtacagaccctaggacctgccaacctgcccctg
acccagcggctgcagtacaactctctgctaagcaacatgagcagaatctactccaccggc
aaggtctgcttccccaacaagactgccacctgctggtccctggacccagagctcaccaac
atcctggcttcctcacgaaactatgccaaggtgctgtttgcctgggaaggctggcatgat
gctgtgggtatcccactgaagcccctctatcaggactttactgccctcagtaatgaagcc
tacagacaagatggcttctcagacacaggagcctactggcgctcctggtatgagtccccc
tcctttgaagagagtttggagcatctctaccaccaagtcgagcccctctacctgaacctc
catgcctttgtccgtcgcgcactgcaccgccgctatggggacaaatacatcaatctcaga
ggtcctattcccgctcatctgctgggagacatgtgggcgcagagctgggagaacatttac
gacatggtagtgcctttcccggacaaacccaacctcgatgtcaccagtacaatggtacag
aagggctggaatgccacgcacatgttccgggtcgcagaggaattctttacctcgctgggg
ctctcccccatgcctccagagttctgggcggagtcgatgctggagaaaccagctgatgga
cgggaggtggtgtgccatgcctctgcgtgggacttctacaacaggaaggacttcaggatt
aagcagtgcacgcgggtcacgatggaccagctgtccacagtacaccacgagatgggccac
gtgcagtactatctccagtacaaggacctgcacgtctctctgcgtcgaggtgccaaccct
ggcttccacgaggccatcggggatgtactcgctctctctgtctctaccccagcacatctg
cacaaaattggcctgctagaccgtgttgccaatgacatagaaagtgacatcaattacttg
ctaaagatggccctagagaaaattgccttcttgccctttggttacctggtggaccagtgg
cgctggggggtcttcagtggacgtaccccaccctctcgctacaactacgactggtggtat
cttcgaaccaagtatcaggggatctgcccaccagttgctcggaatgaaacccattttgac
gctggggccaagtttcacatcccaagcgtgacaccatacatcaggtactttgtgagtttc
gtgctacagttccagttccatcaagcgctgtgcaaggaggcaggccaccagggtccacta
caccagtgtgacatctaccagtccaccaaggcaggggccaagctccaacaggtgctgcag
gctggctgctccaggccctggcaggaggtgctgaaggacctggtgggttcagatgcgctg
gatgccagtgcgctaatggagtacttccaaccagtaagccagtggctgcaggagcagaat
cagcggaatggcgaggtcctaggctggccggagtatcagtggcgtccaccgttaccagac
aactatccagagggaattgacctagagactgatgaagccaaggctaacaggttcgtggag
gagtatgaccggacagccaaggtgttgtggaacgaatacgcagaggccaactggcattat
aacaccaacattaccatagagggcagcaagatcctgcttcagaaaaacaaggaagtgtcc
aaccataccttgaaatatggcacctgggccaagacatttgacgtgagcaacttccagaac
tctaccatcaagcggatcataaagaaggttcagaacgtggaccgggcagtgctgcctccc
aacgagttagaagagtacaaccagatcctgctagacatggagacgacttacagtgtagcc
aatgtttgctacacaaatggcacttgtctgtcactggagcctgatctgacaaatataatg
gccacgtcccggaaatacgaagaattgctttgggtgtggaagagctggcgagacaaggtg
gggagagccatccttccctttttcccaaagtacgtggacttctccaacaagatcgccaag
ctcaacggctactctgatgcaggggattcctggagatcctcatatgagtccgacgacttg
gagcaagacctggaaaaactataccaggagctgcagccgctctacctgaacctgcatgcc
tatgtgcgccgctccctgcaccgccattatgggtctgagtacatcaacctggatggtccc
attcctgctcacctgctagggaacatgtgggcacagacttggtccaacatctatgacttg
gtggcacccttcccttccgcccccagtatagatgccacggaggccatgataaagcaggga
tggacacccagaaggatatttaaggaagctgacaatttttttacctccctggggctgtta
cctgtgccccctgagttctggaacaagtcaatgttagagaagccaaccgatgggagggag
gtggtgtgccatgcctcagcctgggacttctacaacggcaaggacttcaggatcaagcag
tgtacctctgtgaacatggaggaattggtgatagcccaccacgaaatgggccacatccag
tatttcatgcagtacaaagacttgcctgtgacctttcgggagggcgccaaccccggtttt
catgaggctattggagatgttttggctctgtctgtgtctacacccaagcatctacacagt
ctcaacctgctcagcagtgagggcagtggctacgagcatgacatcaactttctaatgaag
atggcccttgacaagatcgccttcatccccttcagctacctcattgaccagtggcgctgg
agggtctttgacggaagcatcaccaaggagaactacaaccaggagtggtggagtctcaga
ctgaagtaccagggtctctgccctccagtgcctagatcccaaggtgactttgacccaggg
tccaagttccacgttcctgcgaatgtgccatacatcaggtactttatcagcttcatcatc
cagttccagttccacgaggcactatgtcgcgcagccgggcacaccggccccctgtacaag
tgtgatatctaccaatccaaggaagcagggaagctgctggcagatgccatgaagttgggc
tacagtaagcagtggccagaagccatgaagataatcacaggccaacctaacatgtcagcc
tctgccattatgaattacttcaagccactgactgaatggctcgtcacagagaacaggaga
catggagagacactgggctggccggagtacacctggacaccaaacacggctcgtgcagaa
ggctccctcccagagtccagtcgcgtcaacttcctgggtatgtacctggaaccacagcag
gcccgtgtgggccagtgggtgctgctcttcctaggcgtcgccctgctggtggccaccgtg
ggtctcgcccaccgactctacaacatccataaccatcacagcctccgccggccccaccgt
gggccccagtttgggtccgaggtggagctcagacactcctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (47)   

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