KEGG   Rattus norvegicus (rat): 24314
Entry
24314             CDS       T01003                                 
Symbol
Nqo1
Name
(RefSeq) NAD(P)H dehydrogenase [quinone] 1
  KO
K00355  NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00130  Ubiquinone and other terpenoid-quinone biosynthesis
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
rno05200  Pathways in cancer
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    24314 (Nqo1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24314 (Nqo1)
   05208 Chemical carcinogenesis - reactive oxygen species
    24314 (Nqo1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    24314 (Nqo1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    24314 (Nqo1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.2  NAD(P)H dehydrogenase (quinone)
     24314 (Nqo1)
SSDB
Motif
Pfam: Flavodoxin_2 FMN_red
Other DBs
NCBI-GeneID: 24314
NCBI-ProteinID: NP_058696
RGD: 2503
Ensembl: ENSRNOG00000012772
UniProt: P05982 A6IZ00
Structure
Position
19:complement(52205374..52220267)
AA seq 274 aa
MAVRRALIVLAHAERTSFNYAMKEAAVEALKKKGWEVVESDLYAMNFNPLISRNDITGEP
KDSENFQYPVESSLAYKEGRLSPDIVAEQKKLEAADLVIFQFPLYWFGVPAILKGWFERV
LVAGFAYTYATMYDKGPFQNKKTLLSITTGGSGSMYSLQGVHGDMNVILWPIQSGILRFC
GFQVLEPQLVYSIGHTPPDARVQVLEGWKKRLETVWEESPLYFAPSSLFDLNFQAGFLLK
KEVQEEQKKNKFGLSVGHHLGKSIPADNQIKARK
NT seq 825 nt   +upstreamnt  +downstreamnt
atggcggtgagaagagccctgattgtattggcccacgcagagaggacatcattcaactat
gccatgaaggaggctgctgtggaggctctgaagaagaaaggatgggaggtggtcgaatct
gacctctatgctatgaactttaaccccctcatttccagaaacgacatcacaggggagccg
aaggactcggagaactttcagtaccctgttgagtcatctctggcgtataaggaaggccgc
ctgagcccggatattgtagctgaacagaaaaagctggaagctgcagacctggtgatattt
cagttcccattgtattggtttggggtgcccgccattctgaaaggctggtttgagagagtg
cttgtagcaggattcgcctacacgtatgccaccatgtatgacaagggtcctttccagaat
aagaagaccttgctttccatcaccaccgggggcagcggctccatgtactctctgcagggt
gtccacggggacatgaacgtcattctctggccaattcagagtggcattctgcgcttctgt
ggcttccaggtcttagaacctcaactggtgtacagcattggccacaccccacccgatgcc
cgcgtgcaggtcctggaagggtggaagaagcgtctggagactgtctgggaggagtcacca
ctctactttgctccaagcagcttgtttgacctaaacttccaggcaggattcttactgaaa
aaagaggttcaagaggagcagaaaaagaacaagtttggcctttctgtgggccatcatttg
ggcaagtccattccagccgacaaccagatcaaagctagaaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   NAGAHAMA-H (2)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (47)   

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