KEGG   Rattus norvegicus (rat): 24398
Entry
24398             CDS       T01003                                 
Symbol
Gls
Name
(RefSeq) glutaminase kidney isoform, mitochondrial isoform a
  KO
K01425  glutaminase [EC:3.5.1.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00220  Arginine biosynthesis
rno00250  Alanine, aspartate and glutamate metabolism
rno00470  D-Amino acid metabolism
rno01100  Metabolic pathways
rno04724  Glutamatergic synapse
rno04727  GABAergic synapse
rno04964  Proximal tubule bicarbonate reclamation
rno05206  MicroRNAs in cancer
rno05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    24398 (Gls)
   00220 Arginine biosynthesis
    24398 (Gls)
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    24398 (Gls)
 09150 Organismal Systems
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    24398 (Gls)
  09156 Nervous system
   04724 Glutamatergic synapse
    24398 (Gls)
   04727 GABAergic synapse
    24398 (Gls)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    24398 (Gls)
   05230 Central carbon metabolism in cancer
    24398 (Gls)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.2  glutaminase
     24398 (Gls)
SSDB
Motif
Pfam: Glutaminase EF-hand_14 Ank_4 Ank_2 Ank Ank_3 Ank_5
Other DBs
NCBI-GeneID: 24398
NCBI-ProteinID: NP_036701
RGD: 2707
Ensembl: ENSRNOG00000056246
UniProt: P13264
Position
9:56836584..56908861
AA seq 673 aa
MMRLRGSAMLRELLLRPPAAVGGVLRRAQPLGTLCRRPRGGSRPAAGLVAAARLHPWWGG
GGRAKGPGSGGLSSSPSEILQELGKGGTPPQQQQQQQQPGASPPAAPGPKDSPGETDAFG
NSEGKEMVAAGDNKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLK
ECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYE
SAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIA
VNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFD
YVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQ
LCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHV
GLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHF
AKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAE
GHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDDGK
ENQTVHKNLDGLL
NT seq 2022 nt   +upstreamnt  +downstreamnt
atgatgcggctgcgaggctcggcgatgctgcgggagctgctcttgaggccgcctgccgcc
gtcggaggcgtcttgcggcgcgcgcagcccctcggcacgctgtgccggcgcccccggggc
gggagccggccggccgctggcctggtggccgctgcgcgactccacccgtggtggggcggg
ggcggccgcgcgaagggcccgggctcgggcggcctgtccagctcgccctcggagatcctg
caggagctgggcaaggggggcacgccgccacagcagcagcagcagcagcagcagccaggg
gcgtcgccacccgcagccccgggccccaaggacagcccgggggagacggacgcgttcggc
aacagcgaaggcaaggagatggtggctgcgggcgacaataaagtaaagcagggtctgtta
cctagcttggaagatttgctgttctatacaattgcagaaggacaagaaaagatacctgtt
cacaagtttattacagcactcaaatctacaggattgcgaacatctgatcccaggttgaaa
gagtgtatggatatgttaagattaactcttcagacaacgtcagatggtgtcatgctagac
aaagatctttttaaaaagtgtgttcaaagcaacatcgttttgttaacacaagcatttaga
agaaagtttgtcatccctgactttatgtcttttacctcacacatcgatgagttatatgaa
agtgctaaaaagcagtctggagggaaggttgctgattatattcctcaactggccaaattc
agtcctgatttgtggggtgtatctgtttgtaccgtagatgggcaaaggcattctattgga
gataccaaagttcccttttgtcttcagtcctgtgtaaagcccctgaaatatgcaattgct
gtcaatgacctgggaactgagtatgtgcatcgctatgttgggaaggagccaagtggatta
agattcaacaagctctttttgaatgaagatgataaaccacataatccgatggtaaatgct
ggagcaattgttgtgacttcactaataaagcaaggagtaaataatgctgagaaatttgac
tatgtgatgcaatttttgaataagatggctggtaatgaatatgtcggattcagtaatgca
acgtttcaatctgaacgagaaagtggagaccgaaattttgcaataggatattacttaaaa
gaaaagaagtgttttccagaaggcacagacatggttgggatactagatttttatttccag
ctctgttccattgaagtgacgtgtgagtcagcaagtgtgatggctgcaaccttggctaat
ggcggtttctgcccaattactggtgaaagagtgctcagtcctgaggccgttcggaatacc
ctgagcttaatgcactcctgtggcatgtatgacttctcagggcagtttgcatttcatgtt
ggtcttcctgcaaaatctggagttgctgggggtattcttttagttgtccccaacgtcatg
ggcatgatgtgttggtctcctcctcttgacaagatgggcaacagtgttaaaggaattcac
ttttgtcacgatcttgtttctctgtgtaacttccataactatgataatttgagacacttt
gcaaaaaaacttgatcctcggagagaaggaggtgatcaaagggtaaagtcggtgataaac
ctcctgtttgctgcgtacactggagatgtgtctgccctccgaaggtttgctctgtcagcc
atggacatggaacagagagattacgactccagaacagccctgcatgttgctgctgcagaa
ggtcatgttgaagttgtgaagtttttgctggaagcttgcaaagttaaccccttccccaag
gacaggtggaataacacccccatggatgaagcactgcactttggacaccatgatgttttt
aaaatcctccaggaataccaagttcagtatacacctcaaggggattctgacgatggaaaa
gaaaaccagactgtccacaagaatcttgacgggttgttataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (25)   
   RefSeq(nuc) (13)   
   GenBank (6)   
   EMBL (6)   
Protein domain (7)   
   Pfam (7)   
All databases (70)   

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