KEGG   Rattus norvegicus (rat): 24408
Entry
24408             CDS       T01003                                 
Symbol
Grin1
Name
(RefSeq) glutamate receptor ionotropic, NMDA 1 isoform 1a precursor
  KO
K05208  glutamate receptor ionotropic, NMDA 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04024  cAMP signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04724  Glutamatergic synapse
rno05010  Alzheimer disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05017  Spinocerebellar ataxia
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05030  Cocaine addiction
rno05031  Amphetamine addiction
rno05033  Nicotine addiction
rno05034  Alcoholism
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    24408 (Grin1)
   04015 Rap1 signaling pathway
    24408 (Grin1)
   04020 Calcium signaling pathway
    24408 (Grin1)
   04024 cAMP signaling pathway
    24408 (Grin1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    24408 (Grin1)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    24408 (Grin1)
   04720 Long-term potentiation
    24408 (Grin1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24408 (Grin1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24408 (Grin1)
   05014 Amyotrophic lateral sclerosis
    24408 (Grin1)
   05016 Huntington disease
    24408 (Grin1)
   05017 Spinocerebellar ataxia
    24408 (Grin1)
   05020 Prion disease
    24408 (Grin1)
   05022 Pathways of neurodegeneration - multiple diseases
    24408 (Grin1)
  09165 Substance dependence
   05030 Cocaine addiction
    24408 (Grin1)
   05031 Amphetamine addiction
    24408 (Grin1)
   05033 Nicotine addiction
    24408 (Grin1)
   05034 Alcoholism
    24408 (Grin1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    24408 (Grin1)
Ion channels [BR:rno04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   24408 (Grin1)
SSDB
Motif
Pfam: Lig_chan ANF_receptor Lig_chan-Glu_bd SBP_bac_3 Ion_trans_2 Peripla_BP_6 DUF6724
Other DBs
NCBI-GeneID: 24408
NCBI-ProteinID: NP_058706
RGD: 2736
Ensembl: ENSRNOG00000011726
UniProt: P35439 A6JT38
Structure
Position
3:complement(28501836..28528754)
AA seq 938 aa
MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQL
NATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLG
LTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRL
ETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNM
TGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKEN
ITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRK
LVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTC
KEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVA
DGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTI
LVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDA
LTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRP
EERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQA
VRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSH
ENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRH
KDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDT
STGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
NT seq 2817 nt   +upstreamnt  +downstreamnt
atgagcaccatgcacctgctgacattcgccctgcttttttcctgctccttcgcccgcgcc
gcctgcgaccccaagatcgtcaacatcggcgcggtgctgagcacgcgcaagcatgaacag
atgttccgcgaggcagtaaaccaggccaataagcgacacggctcttggaagatacagctc
aacgccacttctgtcacccacaagcccaacgccatacagatggccctgtcagtgtgtgag
gacctcatctctagccaggtctacgctatcctagttagccacccgcctactcccaacgac
cacttcactcccacccctgtctcctacacagctggcttctacagaatccctgtcctggga
ctgactacccgaatgtccatctactctgacaagagtatccacctgagtttccttcgcacg
gtgccgccctactcccaccagtccagcgtctggtttgagatgatgcgagtctacaactgg
aaccacatcatcctgctggtcagcgacgaccacgagggacgggcagcgcagaagcgcttg
gagacgttgctggaggaacgggagtccaaggcagagaaggtgctgcagtttgacccagga
accaagaatgtgacggctctgctgatggaggcccgggaactggaggcccgggtcatcatc
ctttctgcaagcgaggacgacgctgccacagtgtaccgcgcagccgcaatgctgaacatg
acgggctctgggtacgtgtggctggtcggggaacgcgagatctctgggaacgccctgcgc
tacgctcctgatggcatcatcggacttcagctcatcaatggcaagaatgagtcagcccac
atcagtgacgccgtgggcgtggtggcacaggcagttcacgaactcctagagaaggagaat
atcactgacccaccgcggggttgcgtgggcaacaccaacatctggaagacaggaccattg
ttcaagagggtgctgatgtcttctaagtatgcggacggagtgactggccgtgtggaattc
aatgaggatggggaccggaagtttgccaactatagtatcatgaacctgcagaaccgcaag
ctggtgcaagtgggcatctacaatggtacccatgtcatcccaaatgacaggaagatcatc
tggccaggaggagagacagagaaacctcgaggataccagatgtccaccagactaaagata
gtgacaatccaccaagagcccttcgtgtacgtcaagcccacaatgagtgatgggacatgc
aaagaggagttcacagtcaatggtgacccagtgaagaaggtgatctgtacggggcctaat
gacacgtccccaggcagcccacgccacacagtgccccagtgctgctatggcttctgcata
gacctgctcatcaagctggcgcggaccatgaattttacctatgaggtgcacctggtggca
gatggcaagtttggcacacaggagcgggtaaacaacagcaacaaaaaggagtggaacgga
atgatgggcgagctactcagtggccaagcggacatgattgtggcaccactgaccatcaac
aatgagcgtgcgcagtacatagagttctccaagcccttcaagtaccagggcctgaccatt
ttggtcaagaaggagattcccaggagcacactggactcatttatgcagccttttcagagc
acactgtggttgctagtaggactgtcagttcatgtggtggctgtgatgctgtacctgctg
gaccgcttcagtccctttggccgattcaaggtgaacagtgaggaggaggaggaagatgca
ctgaccctgtcctctgccatgtggttttcctggggcgtcctgctcaactccggcattggg
gaaggtgccccccggagtttctctgcacgtatcctaggcatggtgtgggctggtttcgcc
atgatcatagtggcttcctacactgccaacttggcagctttcctggtgctggatcggcct
gaggagcgcatcacgggcatcaatgaccccaggctcagaaacccctcagacaagttcatc
tacgcaactgtaaagcagagctccgtggacatctacttccggaggcaggtggagttgagt
accatgtaccggcacatggaaaaacacaattacgagagcgcagctgaggccatccaggct
gtgcgggacaacaagctgcacgcctttatctgggactcggccgtgctggagtttgaggct
tcacagaagtgcgatctggtgaccacgggtgagctgttcttccgctcaggctttggcatc
ggcatgcgcaaggacagcccctggaagcagaacgtttccctgtccatactcaagtcccat
gagaatggcttcatggaagatctggataagacatgggttcggtatcaggaatgcgactcc
cgcagcaatgctcctgcaaccctcacttttgagaacatggcaggggtcttcatgctggtg
gctggaggcatcgtagctgggattttcctcattttcattgagatcgcctacaagcgacac
aaggatgcccgtaggaagcagatgcagctggcttttgcagccgtgaacgtgtggaggaag
aacctgcaggatagaaagagtggtagagcagagcccgaccctaaaaagaaagccacattt
agggctatcacctccaccctggcctccagcttcaagagacgtaggtcctccaaagacacg
agcaccgggggtggacgcggcgctttgcaaaaccaaaaagacacagtgctgccgcgacgc
gctattgagagggaggagggccagctgcagctgtgttcccgtcatagggagagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (18)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (36)   
   RefSeq(nuc) (8)   
   GenBank (14)   
   EMBL (14)   
3D Structure (85)   
   PDB (85)   
Protein domain (7)   
   Pfam (7)   
All databases (166)   

Download RDF
DBGET integrated database retrieval system