KEGG   Rattus norvegicus (rat): 24423
Entry
24423             CDS       T01003                                 
Symbol
Gstm1
Name
(RefSeq) glutathione S-transferase Mu 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    24423 (Gstm1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    24423 (Gstm1)
   00982 Drug metabolism - cytochrome P450
    24423 (Gstm1)
   00983 Drug metabolism - other enzymes
    24423 (Gstm1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24423 (Gstm1)
   05204 Chemical carcinogenesis - DNA adducts
    24423 (Gstm1)
   05207 Chemical carcinogenesis - receptor activation
    24423 (Gstm1)
   05208 Chemical carcinogenesis - reactive oxygen species
    24423 (Gstm1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    24423 (Gstm1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    24423 (Gstm1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    24423 (Gstm1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    24423 (Gstm1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     24423 (Gstm1)
Transporters [BR:rno02000]
 Other transporters
  Pores ion channels [TC:1]
   24423 (Gstm1)
SSDB
Motif
Pfam: GST_C GST_N GST_C_3 GST_C_6 GST_N_3 GST_N_2 GST_C_2 GST_N_4
Other DBs
NCBI-GeneID: 24423
NCBI-ProteinID: NP_058710
RGD: 2755
Ensembl: ENSRNOG00000029726
UniProt: P04905
Structure
Position
2:complement(198338005..198346007)
AA seq 218 aa
MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF
EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN
LKDFLARFEGLKKISAYMKSSHYLSTPIFSKLAQWSNK
NT seq 657 nt   +upstreamnt  +downstreamnt
atgcctatgatactgggatactggaacgtccgcgggctgacacacccgatccgcctgctc
ctggaatacacagactcaagctatgaggagaagagatacgccatgggcgacgctcccgac
tatgacagaagccagtggctgaatgagaagttcaaactgggcctggacttccccaatctg
ccctacttaattgatggatcgcgcaagattacccagagcaatgccataatgcgctacctt
gcccgcaagcaccacctgtgtggagagacagaggaggagcggattcgtgcagacattgtg
gagaaccaggtcatggacaaccgcatgcagctcatcatgctttgttacaaccccgacttt
gagaagcagaagccagagttcttgaagaccatccctgagaagatgaagctctactctgag
ttcctgggcaagcgaccatggtttgcaggggacaaggtcacctatgtggatttccttgct
tatgacattcttgaccagtaccacatttttgagcccaagtgcctggacgccttcccaaac
ctgaaggacttcctggcccgcttcgagggcctgaagaagatctctgcctacatgaagagc
agccactacctctcaacacctatattttcgaagttggcccaatggagtaacaagtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   PROTHERM (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (43)   
   RefSeq(nuc) (3)   
   GenBank (20)   
   EMBL (20)   
3D Structure (15)   
   PDB (15)   
Protein domain (8)   
   Pfam (8)   
All databases (162)   

Download RDF
DBGET integrated database retrieval system