KEGG   Rattus norvegicus (rat): 24565
Entry
24565             CDS       T01003                                 
Symbol
Abcc1
Name
(RefSeq) multidrug resistance-associated protein 1
  KO
K05665  ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01523  Antifolate resistance
rno02010  ABC transporters
rno04071  Sphingolipid signaling pathway
rno04977  Vitamin digestion and absorption
rno05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    24565 (Abcc1)
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    24565 (Abcc1)
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    24565 (Abcc1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    24565 (Abcc1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    24565 (Abcc1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    24565 (Abcc1)
Enzymes [BR:rno01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.3  ABC-type glutathione-S-conjugate transporter
     24565 (Abcc1)
Transporters [BR:rno02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
    24565 (Abcc1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N AAA_16 MMR_HSR1 AAA_22 AAA_25 RsgA_GTPase nSTAND1 ABC_ATPase AAA_29 Zeta_toxin Dynamin_N
Other DBs
NCBI-GeneID: 24565
NCBI-ProteinID: NP_071617
RGD: 3112
Ensembl: ENSRNOG00000022305
UniProt: Q8CG09
Position
10:complement(1022041..1162431)
AA seq 1532 aa
MALSSFCSSDGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFLYLSRH
DRGYIQMTHLNKAKTALGFFLWIICWADLFYSFWERSQGMLLAPVLLVSPTLLGITMLLA
TFLIQFERRKGVQSSGIMLTFWLVALLCALAILRSKIISALKKDAQVDMFRDSAFYLYFT
LVFIQLVLSCFSDSSPLFSETVRDPNPCPESSASFLSRITFWWITGMMVQGYRQPLKSSD
LWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEA
LIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLMMFAGPEILELIINFVNDREAP
DWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSST
VGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPF
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVL
KKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNIL
PMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDEPP
TLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQN
DSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLA
RAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVII
VMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENG
ILVTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAELQKSGVKEETWKLMEADKAQTGQVKL
SVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQENRNFRLSVY
GALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKE
LDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQ
LKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWL
AVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIV
AVERLKEYSETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEG
GEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVL
FSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVC
LARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIV
LDKGEIRECGAPSELLQQRGVFYSMAKDAGLV
NT seq 4599 nt   +upstreamnt  +downstreamnt
atggcgctgagcagcttctgcagctctgatggctccgatccgctctgggattggaatgtc
acatggcacaccagcaaccctgactttaccaagtgctttcagaatacggtcctcacatgg
gtgccttgtttctacctctggtcctgtttccccctctacttcctctatctctctcgacat
gaccggggctacatccagatgacacacctcaacaaagccaaaactgccttaggattcttt
ctgtggatcatctgctgggcagacctcttctactctttctgggaaagaagtcagggaatg
ctcctagccccggtgctactggtcagcccgacactgctaggcatcaccatgctgctcgcc
acctttttaattcagtttgagcgaaggaaaggagtccagtcctcagggataatgcttact
ttctggcttgtagccctactctgcgcccttgccatcttgagatctaagatcatctctgcc
ttaaaaaaggatgctcaagtggacatgtttcgagattctgcattctatctctacttcacc
ctcgtgttcattcagcttgtgctgtcctgcttctcagacagctcacccttgttctctgaa
actgtccgtgacccgaatccatgtccagaatcgagtgcctcttttctttccaggatcact
ttttggtggattacagggatgatggtgcagggctaccgccagcccctgaagagcagtgac
ctctggtcattgaataaagaggacacgtcagaagaagtggtacctgtgctggtgaataac
tggaagaaggaatgtgttaagtcgaggaagcagcctgtacggattgtgtatgcccctccc
aaagatcccaccaagcctaagggaagttctcagttggatgtgaatgaggaagtggaggca
ctgattgtcaagtcatcccacaaggaccgggacccctctctgttcaaggtgttgtacaag
acctttgggccctacttcctcatgagcttcctgtacaaggcccttcatgacctgatgatg
tttgctggccctgagatcttggaattgattatcaacttcgtgaatgacagggaggcccct
gactggcagggctacttgtacacagcactgctgtttgtcagtgcctgtctgcagacactg
gcactccaccagtactttcatatctgcttcgtcaccggcatgcgcatcaagactgctgtg
gtgggtgctgtttaccgcaaggctcttgtgatcaccaattcagctagaaaatcgtccaca
gttggagagattgtcaacctcatgtccgtggatgcccagcgcttcatggacttggccacg
tatattaacatgatctggtcagcccctctgcaagtcaccctagccctctacttcctgtgg
ctgaacctgggcccttctgtgctggctggggtggctgttatgatcctcatggtgcccttc
aatgctgtgatggccatgaagaccaagacttaccaggtggcacacatgaagagcaaagac
aaccgaatcaagctgatgaacgagatcctcaatgggatcaaagtactcaaattgtacgcc
tgggagctggctttccaggacaaagttatgaacatcaggcaggaggagctgaaggtgctg
aagaaatccgcctacctggcggctgtgggcacattcacatgggtttgcacacctttcctg
gtggctctgtcaacctttgctgtctttgtgactgtggacgagaagaacatcctagatgca
aagaaagcctttgtatccctagccctgttcaatatcttgcgcttcccactcaacatccta
cccatggtcatcagcagcattgtgcaggccagcgtgtccctcaagcgtctcaggatcttt
ctgtctcacgaggagctggagccagacagcatcgagcgatggtcgatcaaggatggtgga
gggatgaatagcatcactgtgaagaatgcaaccttcacttgggccagggatgaacctccc
acactgaatggcatcaccttcgccatccctgatggagcccttgtggccgtggtgggccag
gtaggctgtgggaagtcatctctgctgtcagccctgctggctgagatggacaaagtggag
ggacatgtgactctcaagggctccgtggcctatgtgccccagcaggcctggattcagaat
gactctctccgagagaacatactgtttgggcgccccctgcaggaacattgctacaaggcg
gtgatggaagcctgtgccctccttccggatttggaaatccttcccagtggggacctcaca
gagattggtgagaagggtgtgaacctgtcggggggccagaagcagcgtgtgagcctggct
cgggctgtgtattgtaactctgacatctacctcttggacgaccccctctcggctgtggat
gcacatgttgggaagcacatctttgagaaggtggtgggtcccatgggcctactgaagaac
aagacacggatcctggtcacccatggtatcagctacctgccccaagtggatgtcatcatt
gtcatgagtggcggcaagatctcagagatgggatcttatcaggagctgctagaccgggat
ggggcctttgctgagttcgtgcgcacctatgccaacactgagcaggacctggcttcagag
gatgacagtaagaatggtgtcagtggtttagggaaggagtcaaagccggtggaaaatggg
atactggtgacagacgcagtagggaagcccctgcagaggcatctcagcaactcttcttcc
cacagtgtggttactaaccagcagcacagcagcacagccgagctgcagaagtctggagtt
aaggaggagacttggaagctgatggaagcagacaaggcccagacagggcaggtgaagctt
tccgtgtactggaactacatgaaggccattggcctctgcatctccttcttgagtatcttc
cttttcctgtgcaatcatgtatctgcactggcttctaactattggctgagtctctggaca
gatgaccgccctgctgtcaatgggactcaggagaacaggaattttcgactaagtgtctat
ggggccttgggcatcttgcaaggtgtggcagtatttggctattccatggctgtgtccatt
gggggcatctttgcctcccgtcgcctgcacctagacctgctacagaatgtcctgcgatca
cccatgagtttctttgagcgtacacccagtgggaacctagtgaaccgattctccaaggag
ttggacacagtggactccatgatcccgcaggtcatcaagatgttcatgggttcactcttc
agtgtcattggagctgtcatcatcatcctactggctacgcccattgccgcagtcatcatc
ccacccttgggtctggtttacttctttgtgcagaggttctatgtggcctcctctcgacag
ctgaagcgcctggagtctgtcagtcgttcccctgtgtactcacacttcaatgagaccttg
ctgggggtcagtgtcatccgtgcctttgaggaacaggagcgcttcattcgccaaagtgac
ctgaaagtagatgagaaccagaaggcctactaccccagcattgtggccaacaggtggctt
gctgtgcgcctggagtgtgtgggcaactgcattgtgctgtttgctgcccttttcgcagtc
atctcccggcatagcctcagtgctggcttggtgggtctctctgtgtcttactcactgcag
ataactgcatacttgaactggctagttcgaatgtcctctgagatggagaccaacattgtg
gcagtggagagactgaaggaatattctgaaacggagaaggaggcttcttggcaaatccaa
gagacagctccacccagcacctggccccattcaggccgtgtagagttccgggattactgc
ttgaggtatcgagaagacttggacttggttctcaagcacataaatgtcaccattgagggt
ggagaaaaggttggtattgtgggtcgtacaggagctgggaaatcatctctcaccctgggt
ttgttccggatcaatgagtctgcagaaggggagatcatcattgatgggataaacattgct
aagattggcctgcacaacctgcgcttcaagatcaccatcattccacaggatcctgttttg
ttctcgggttccctccgcatgaacctggaccctttcagtcagtattctgatgaagaagtc
tggatggctctggagcttgctcacctgaagggctttgtgtcagccttgcctgacaagctg
aaccatgagtgtgcagaaggtggagagaatctgagtgtggggcagcgacagcttgtgtgc
ctggcccgggctttgctgaggaagacaaagattctagtgttggacgaggctacagcagct
gtggatctggagacagatgaccttattcagtccaccatccggacgcagtttgaagacagt
actgtgctcactattgctcatcggctgaataccataatggactatacaagggtgattgtc
ctggacaaaggagaaattcgggagtgtggtgcaccctctgagctcctgcagcaaagaggc
gtcttctatagcatggccaaggatgctggcttggtgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (28)   
   RefSeq(nuc) (14)   
   GenBank (7)   
   EMBL (7)   
Protein domain (13)   
   Pfam (13)   
All databases (72)   

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