KEGG T01003: 24640

Rattus norvegicus (rat): 24640

Entry

24640             CDS       T01003

Symbol

Pfkfb2

Name

(RefSeq) 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform a

K19029

6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]

Organism

rno Rattus norvegicus (rat)

Pathway

rno00051

Fructose and mannose metabolism

rno01100

Metabolic pathways

rno04152

AMPK signaling pathway

rno04919

Thyroid hormone signaling pathway

Brite

KEGG Orthology (KO) [BR:rno00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    24640 (Pfkfb2)
09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    24640 (Pfkfb2)
09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    24640 (Pfkfb2)
Enzymes [BR:rno01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.105  6-phosphofructo-2-kinase
     24640 (Pfkfb2)
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.46  fructose-2,6-bisphosphate 2-phosphatase
     24640 (Pfkfb2)

SSDB

Motif

Pfam:

6PF2K His_Phos_1 AAA_33 KTI12 His_Phos_2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

RGD:

Ensembl:

UniProt:

Position

13:complement(44683499..44727135)

AA seq 557 aa
MSENSTFSTEDSSSSSYKPHASNLRRAGKKCSWASYMTNSPTLIVMIGLPARGKTYVSKK
LTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYF
TEESGQIAVFDATNTTRERRDMILNFAKQNAFKVFFVESVCDDPDVIAANILEVKVSSPD
YPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVMNVGQRFLVNRVQDYIQSK
IVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSLRGKQFAQALKKFLEEQEIQDL
KVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYL
YRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPL
HIIFKLTPVAYGCKVETITLNVEAVDTHRDKPTHNFPKSQTPVRMRRNSFTPLSSSNTIR
RPRNYSVGSRPLKPLSPLRALDMQEGADQPKTQVQQGSAQATEHLQKALEFANGHREVEN
VLAKHRRPSMASLTLLS

NT seq 1674 nt +upstreamnt +downstreamnt
atgtctgagaatagtacattttccacagaagacagcagcagcagcagctataaaccccac
gcctcaaacctccgaagggcagggaagaaatgctcatgggcttcctacatgaccaactcc
ccaacactcattgttatgattggcttgccagcccggggtaagacttatgtgtccaagaaa
ttaacacgctacctgaactggattggagtacctaccaaagtgtttaatcttggtgtatat
cgacgggaagcagtcaagtcctataagtcctatgacttctttcgacatgacaatgaagag
gccatgaagatccgcaaacagtgtgccctggtggcactggaagatgtgaaggcctacttt
actgaagagagtgggcagatcgcggtgtttgatgccaccaataccactcgggagaggagg
gacatgattttgaactttgccaagcagaatgccttcaaggtattctttgtggaatctgtg
tgtgatgatcctgatgtcattgctgccaatattctggaggtaaaagtgtcaagccctgac
taccccgaaaggaatagggagaatgtgatggaggacttcctgaagagaattgagtgctac
aaggtcacttaccagccccttgacccagacaactatgataaggacctctcgttcataaag
gtgatgaatgtaggccagaggtttctggtcaacagagttcaggactacatccagagtaag
attgtctactacctgatgaacatccatgtccatcctcgcaccatctatctgtgccggcac
ggagagagcgaattcaatcttttgggaaagattgggggtgactctggcctttcgttgcga
ggaaagcagtttgctcaggctctgaagaagtttctggaggaacaggagatccaggacctc
aaagtgtggacaagccagttgaagaggacaattcagactgctgagtctcttggggtgacc
tatgagcaatggaagatcctaaatgagattgatgctggcgtgtgtgaggagatgacttat
tcggagatcgaacaacggtatccagaggaatttgcacttcgagatcaagagaagtatctg
tatcgatatcctggtggggagtcataccaggacctggtgcagcggctggagcctgtgatc
atggagctggagcggcaaggcaacgtcctcgttatctctcaccaggctgtcatgcgctgc
ctcctggcctacttcttggataaaggcgcagatgagttgccgtacttgaggtgccccctc
cacatcatcttcaaacttactcctgtggcctatggttgcaaagtggaaacaattacactg
aatgtggaagctgtggacacacatcgtgacaagccaactcacaacttccccaagagccaa
acccctgtaaggatgagaaggaacagctttacgcctctgtccagttcgaacacaataagg
cgtccaagaaattacagtgttgggagccgacccctcaagcccctcagccctctccgtgcc
ctggatatgcaagaaggggcggaccagccgaagacccaagtccagcaagggtcagcccag
gctacagaacatctacagaaagccctggagtttgcaaatggacatagggaagtggagaat
gtgctggctaagcatagacgcccctcaatggcatccctcactttgctctcctga

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