KEGG   Rattus norvegicus (rat): 24681
Entry
24681             CDS       T01003                                 
Symbol
Prkcg
Name
(RefSeq) protein kinase C gamma type
  KO
K19663  classical protein kinase C gamma type [EC:2.7.11.13]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01521  EGFR tyrosine kinase inhibitor resistance
rno04010  MAPK signaling pathway
rno04012  ErbB signaling pathway
rno04014  Ras signaling pathway
rno04015  Rap1 signaling pathway
rno04020  Calcium signaling pathway
rno04066  HIF-1 signaling pathway
rno04070  Phosphatidylinositol signaling system
rno04071  Sphingolipid signaling pathway
rno04150  mTOR signaling pathway
rno04270  Vascular smooth muscle contraction
rno04310  Wnt signaling pathway
rno04370  VEGF signaling pathway
rno04510  Focal adhesion
rno04540  Gap junction
rno04613  Neutrophil extracellular trap formation
rno04650  Natural killer cell mediated cytotoxicity
rno04666  Fc gamma R-mediated phagocytosis
rno04670  Leukocyte transendothelial migration
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04730  Long-term depression
rno04750  Inflammatory mediator regulation of TRP channels
rno04911  Insulin secretion
rno04916  Melanogenesis
rno04918  Thyroid hormone synthesis
rno04919  Thyroid hormone signaling pathway
rno04921  Oxytocin signaling pathway
rno04925  Aldosterone synthesis and secretion
rno04928  Parathyroid hormone synthesis, secretion and action
rno04929  GnRH secretion
rno04935  Growth hormone synthesis, secretion and action
rno04960  Aldosterone-regulated sodium reabsorption
rno04961  Endocrine and other factor-regulated calcium reabsorption
rno04970  Salivary secretion
rno04971  Gastric acid secretion
rno04972  Pancreatic secretion
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
rno05031  Amphetamine addiction
rno05032  Morphine addiction
rno05143  African trypanosomiasis
rno05146  Amoebiasis
rno05161  Hepatitis B
rno05163  Human cytomegalovirus infection
rno05170  Human immunodeficiency virus 1 infection
rno05171  Coronavirus disease - COVID-19
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05206  MicroRNAs in cancer
rno05207  Chemical carcinogenesis - receptor activation
rno05214  Glioma
rno05223  Non-small cell lung cancer
rno05225  Hepatocellular carcinoma
rno05231  Choline metabolism in cancer
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    24681 (Prkcg)
   04012 ErbB signaling pathway
    24681 (Prkcg)
   04014 Ras signaling pathway
    24681 (Prkcg)
   04015 Rap1 signaling pathway
    24681 (Prkcg)
   04310 Wnt signaling pathway
    24681 (Prkcg)
   04370 VEGF signaling pathway
    24681 (Prkcg)
   04066 HIF-1 signaling pathway
    24681 (Prkcg)
   04020 Calcium signaling pathway
    24681 (Prkcg)
   04070 Phosphatidylinositol signaling system
    24681 (Prkcg)
   04071 Sphingolipid signaling pathway
    24681 (Prkcg)
   04150 mTOR signaling pathway
    24681 (Prkcg)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    24681 (Prkcg)
   04540 Gap junction
    24681 (Prkcg)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    24681 (Prkcg)
   04650 Natural killer cell mediated cytotoxicity
    24681 (Prkcg)
   04666 Fc gamma R-mediated phagocytosis
    24681 (Prkcg)
   04670 Leukocyte transendothelial migration
    24681 (Prkcg)
  09152 Endocrine system
   04911 Insulin secretion
    24681 (Prkcg)
   04929 GnRH secretion
    24681 (Prkcg)
   04921 Oxytocin signaling pathway
    24681 (Prkcg)
   04935 Growth hormone synthesis, secretion and action
    24681 (Prkcg)
   04918 Thyroid hormone synthesis
    24681 (Prkcg)
   04919 Thyroid hormone signaling pathway
    24681 (Prkcg)
   04928 Parathyroid hormone synthesis, secretion and action
    24681 (Prkcg)
   04916 Melanogenesis
    24681 (Prkcg)
   04925 Aldosterone synthesis and secretion
    24681 (Prkcg)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    24681 (Prkcg)
  09154 Digestive system
   04970 Salivary secretion
    24681 (Prkcg)
   04971 Gastric acid secretion
    24681 (Prkcg)
   04972 Pancreatic secretion
    24681 (Prkcg)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    24681 (Prkcg)
   04961 Endocrine and other factor-regulated calcium reabsorption
    24681 (Prkcg)
  09156 Nervous system
   04724 Glutamatergic synapse
    24681 (Prkcg)
   04727 GABAergic synapse
    24681 (Prkcg)
   04725 Cholinergic synapse
    24681 (Prkcg)
   04728 Dopaminergic synapse
    24681 (Prkcg)
   04726 Serotonergic synapse
    24681 (Prkcg)
   04720 Long-term potentiation
    24681 (Prkcg)
   04730 Long-term depression
    24681 (Prkcg)
   04723 Retrograde endocannabinoid signaling
    24681 (Prkcg)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    24681 (Prkcg)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24681 (Prkcg)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    24681 (Prkcg)
   05206 MicroRNAs in cancer
    24681 (Prkcg)
   05205 Proteoglycans in cancer
    24681 (Prkcg)
   05207 Chemical carcinogenesis - receptor activation
    24681 (Prkcg)
   05231 Choline metabolism in cancer
    24681 (Prkcg)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    24681 (Prkcg)
   05214 Glioma
    24681 (Prkcg)
   05223 Non-small cell lung cancer
    24681 (Prkcg)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    24681 (Prkcg)
   05161 Hepatitis B
    24681 (Prkcg)
   05171 Coronavirus disease - COVID-19
    24681 (Prkcg)
   05163 Human cytomegalovirus infection
    24681 (Prkcg)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    24681 (Prkcg)
   05143 African trypanosomiasis
    24681 (Prkcg)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    24681 (Prkcg)
   05022 Pathways of neurodegeneration - multiple diseases
    24681 (Prkcg)
  09165 Substance dependence
   05031 Amphetamine addiction
    24681 (Prkcg)
   05032 Morphine addiction
    24681 (Prkcg)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    24681 (Prkcg)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    24681 (Prkcg)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    24681 (Prkcg)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     24681 (Prkcg)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   24681 (Prkcg)
SSDB
Motif
Pfam: Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like
Other DBs
NCBI-GeneID: 24681
NCBI-ProteinID: NP_036760
RGD: 3397
Ensembl: ENSRNOG00000054371
UniProt: P63319 A6KS41
Structure
Position
1:complement(74748272..74777611)
AA seq 697 aa
MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG
SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL
HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD
LKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS
FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS
GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL
VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM
NT seq 2094 nt   +upstreamnt  +downstreamnt
atggcgggtctgggtcctggcgggggcgactcagaagggggaccccgacccctgttttgc
agaaagggggcgctgaggcagaaggtggtccacgaggtgaagagccacaagttcaccgct
cgtttcttcaagcagccaaccttctgcagtcactgtaccgacttcatctggggcattgga
aagcagggcctgcaatgtcaagtctgcagctttgtggttcaccgccgatgccacgaattt
gtgaccttcgagtgtccaggcgctggaaagggcccccagacggacgaccctcgcaacaag
cacaagttccgtctgcacagctacagcagtcccaccttctgcgaccactgtggttccctc
ctctacgggctggtgcaccagggcatgaaatgttcctgttgcgaaatgaatgtgcaccga
cgctgtgtgcgcagcgtgccctccctttgcggcgtggaccatacagagcgccgtggacgt
ctgcaactggaaatccgggctcccacatcagatgagatccatattactgtgggtgaggcc
cggaacctcattcctatggaccccaatggcctgtctgatccctatgtgaaactgaagctc
atcccggaccctcggaacctgacaaaacagaagacaaagaccgtgaaagccacactgaat
cccgtgtggaacgagaccttcgtgttcaacctgaagccgggggatgtggagcgccggctc
agtgtggaggtgtgggattgggataggacatcccgaaatgacttcatgggtgccatgtcc
tttggtgtctcagagctactcaaggctcctgtggatggatggtacaagttactgaaccag
gaggagggcgagtattacaatgtaccggtggccgatgctgacaactgcagcctcctccag
aagtttgaggcctgtaattaccccttggaattgtatgagagagtgcggatgggcccctct
tcctctcccattccttctccatcccccagtcccacggactccaagagatgcttcttcggt
gccagcccaggacgcctgcatatctctgacttcagcttcctcatggttctagggaaaggc
agttttgggaaggtgatgctggcagagcgcagaggatccgatgaactctatgccatcaag
atactgaaaaaagacgtcattgtccaggatgatgatgtagactgcacccttgtggagaag
cgtgtgctggcattgggaggccgaggtcctggaggccggccacactttctcacacaactt
cattccacctttcagactccggaccgcctgtattttgtgatggagtacgtcactgggggc
gatttaatgtaccacattcagcaactgggcaagtttaaggagccccacgcagcattctat
gccgcggaaatcgccataggcctcttcttccttcacaaccagggcatcatctacagggac
ctcaagttggataatgtgatgctggatgctgaaggacacatcaagatcacagacttcggc
atgtgtaaagagaatgtcttccctgggtccacaacccgcaccttctgtgggaccccagac
tacatagcacctgagatcattgcctatcagccctatgggaagtctgtcgactggtggtcc
tttggagtcctgctgtatgagatgttggcaggacagccaccctttgatggggaagatgag
gaggagctgtttcaagccatcatggaacaaactgtcacctatcccaagtcactttcccgg
gaagctgtggccatctgcaaggggttcctgaccaagcacccaggaaagcgcctgggctca
gggccagatggggaacccaccatccgggctcatggctttttccgttggatcgattgggag
aggttggagagactggaaattgcgcctccttttagaccacgtccgtgtggccgcagcggc
gaaaactttgacaagttcttcacgcgggcagcgccagccttgaccccgccagaccgcttg
gtcctagccagcatcgaccaagctgatttccagggctttacttatgtgaacccggacttc
gtgcacccagatgcccgcagccccacaagccctgtgcctgtgcccgtcatgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (62)   
   KEGG PATHWAY (62)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (99)   

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