KEGG   Rattus norvegicus (rat): 24941
Entry
24941             CDS       T01003                                 
Symbol
Atp7a
Name
(RefSeq) copper-transporting ATPase 1
  KO
K17686  P-type Cu+ transporter [EC:7.2.2.8]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno01524  Platinum drug resistance
rno04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    24941 (Atp7a)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    24941 (Atp7a)
Enzymes [BR:rno01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     24941 (Atp7a)
SSDB
Motif
Pfam: HMA E1-E2_ATPase Hydrolase DUF6286 Hydrolase_3 Hydrolase_6 HAD_2
Other DBs
NCBI-GeneID: 24941
NCBI-ProteinID: NP_434690
RGD: 2179
Ensembl: ENSRNOG00000061367
Vega: OTTRNOG00000001771
UniProt: P70705 A6IV40
Position
X:75159635..75267094
AA seq 1492 aa
MEPNMDANSITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATVIYNPKLQTPK
TLQEAIDDMGFDALLHNANPLPVLTNTVFLTVTAPLALPWDHIQSTLLKTKGVTGVKISP
QQRSAVVTIIPSVVSANQIVELVPDLSLDMGTQEKKSGTSEEHSTPQAGEVLLKMRVEGM
TCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKKQIEAVGFPAFIKK
QPKYLKLGAIDVERLKSTPVKSSEGSQQKSPAYPSDSAITFTIDGMHCKSCVSNIESALS
TLQYVSSIVVSLENRSAIVKYNASLVTPEILRKAIEAVSPGQYRVSISSEVESPTSSPSS
SSLQKMPLNLVSQPLTQEVVININGMTCNSCVQSIEGVISKKPGVKSIHVSLTNSTGTIE
YDPLLTSPEPLREAIEDMGFDAVLPADMKEPLVVIAQPSLETPLLPSTTEPENVMTPVQN
KCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAELIRE
LGFGAVVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKY
DPEIIGPRDIIHTIGNLGFEASLVKKDRSANHLDHKREIKQWRGSFLVSLFFCIPVMGLM
IYMMVMDHHLATLNHNQNMSNEEMINMHSSMFLERQILPGLSIMNLLSLLLCLPVQFCGG
WYFYIQAYKALRHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPITFFDTPPMLF
VFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDII
KVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVG
ADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVE
AYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKG
GEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNKISRNKILAIVGTAESNSEHPL
GAAVTKYCKQELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLV
QIDAINEQSSPSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHER
RGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQV
GITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMASVGIAIGTGTDVAIEA
ADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFLPIGLVLQPWM
GSAAMAASSVSVVLSSLFLKLYRKPTYDNYELRPRSHTGQRSPSEISVHVGIDDTSRNSP
RLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTTL
NT seq 4479 nt   +upstreamnt  +downstreamnt
atggaaccaaatatggatgcaaattcaattactatcactgttgagggaatgacatgtatt
tcctgtgtccggaccattgagcagcagattgggaaagtgaatggtgtccatcacattaaa
gtttccctagaagaaaaaagtgcaactgttatttataaccctaaacttcagactccaaag
accctccaagaagctatcgatgacatgggctttgatgctcttcttcacaatgctaaccct
cttcctgtcttaaccaatactgtgtttctgactgttactgctccactggctctgccatgg
gaccatatccaaagtacattgctcaagaccaagggtgtgactggggttaagatttcccct
cagcaaagaagtgcagtggttaccataatcccatctgtggtgagtgctaatcagatcgtg
gagctggtcccagacctcagtttagacatgggaactcaggagaaaaagtcaggaacttct
gaagagcatagcacacctcaggcaggggaagtcctgctgaagatgagagtggaagggatg
acctgccattcatgcactagcaccattgaaggaaaagttggaaagctgcaaggtgtacaa
cgcattaaagtgtccctagacaaccaagaagctactattgtgtatcaacctcatctgatc
acagcagaggaaataaagaagcagattgaagctgtgggttttccagccttcataaaaaaa
cagccaaagtacctcaaattgggagccattgacgttgagcgcctgaagagtacaccagtc
aaatcttcagaaggatctcagcaaaagagcccagcgtatcccagtgactcagcaatcaca
tttaccatagacggcatgcattgtaaatcatgtgtgtcaaatatcgaaagtgctttatct
acactccagtatgtaagcagcatagtagtttctttagagaataggtcagccattgtaaag
tacaatgcaagcttagtcactccagaaatactgagaaaagcgatagaggccgtttctcca
gggcaatacagagttagtatttcaagtgaagttgaaagtcccaccagctctccctccagc
tcatctcttcagaagatgcctttgaacttagtgagccagcctctgacccaagaagttgta
atcaacattaatggcatgacttgtaattcttgtgtgcagtcgatagagggtgtaatatcg
aagaagccaggtgtaaaatccatccacgtttccctcacaaatagcaccgggactattgaa
tatgatcctctactaacctctccagaacccttgcgagaagcaattgaagacatgggattt
gatgctgtccttccagcagacatgaaagagccactggtcgtgatagctcagccctcactg
gaaacacctcttttgccctcaactactgagccagaaaatgtgatgacaccagttcagaac
aagtgttacatacaggtctcggggatgacgtgtgcttcttgtgtagcaaacattgaacgg
aacttaagacgagaagaaggaatatattctgtacttgtagccctaatggctggcaaggcg
gaagtaagatataacccagctgttatccaaccccgagtgatagcagagcttattcgagag
cttggctttggagctgtggtgatggaaaatgctggagaaggcaatggcattttggaactt
gttgtgagaggaatgacgtgtgcctcctgtgtccataaaattgaatcaacgctcacaaaa
cacaaagggatcttctactgctctgtggccctggcaacgaacaaagcacatattaaatat
gatccagaaattattggtcccagagatattatccataccattggaaacttaggttttgaa
gcttctttggtcaagaaagatcgatcagccaaccacttagatcataaacgagaaataaaa
caatggagagggtctttccttgtgagcctgtttttctgtatccctgtaatgggactgatg
atctatatgatggttatggaccaccaccttgcaactctaaaccataatcagaacatgagt
aatgaagaaatgatcaacatgcattcttctatgttcctggagcgtcagatcctgccggga
ctgtccattatgaatttgttgtcccttttattgtgtctacctgtacagttttgtggaggc
tggtacttttacattcaggcttacaaagcgctgaggcataagacagcaaatatggatgtg
ctgattgtgttggcaaccaccattgcatttgcctactctctggtcattcttctggttgca
atgtatgagagagccaaagtgaaccctattaccttctttgatacacctcctatgctgttt
gtgtttatcgcactaggccgatggctggaacacatagcgaagggcaaaacttccgaggct
cttgcaaagctaatttccttacaagcaacagaagcaactattgtaactcttaactctgaa
aatctcctcctgagtgaagaacaagtggatgtggaacttgtacaacgtggagatatcatt
aaggtcgttccaggaggcaaatttccagtggatggccgtgttattgaagggcattctatg
gtagacgagtccctcatcacaggggaagcaatgcctgtggctaagaaacctggcagcacg
gtgattgcaggttccattaaccagaatggatcgctcctcatccgggcaacacacgtaggg
gcagatacaacactttctcaaattgtcaaacttgtagaggaggcacagacatcaaaggct
cctatccagcagtttgcagacaaactcagtggctactttgttccttttatcgtcttggtt
tccattgttaccctcttggtgtggattataattggatttcaaaattttgaaattgtggaa
gcctactttcccggctacaacagaagcatctcccgaacagaaaccataatccgctttgct
ttccaagcgtctatcacagttctgtgtatcgcatgtccctgttcactggggctagccact
ccaactgctgtgatggtgggcacaggagtaggtgctcagaatggcatacttatcaaaggt
ggggagccactggagatggctcataaggtaaaggtagtggtgtttgacaagactggaacc
attacccatggaaccccagtagtgaaccaagtaaaggttctggtggaaagtaacaagata
tcacgcaataagatcctggccattgtgggaactgcagaaagtaacagtgaacatccttta
ggagcagctgtaaccaaatattgcaagcaggagctggacactgaaaccttgggtacctgc
acagatttccaggttgtacccggctgtggaattagctgtaaagtcaccaatattgaaggt
ttgctacataagagtaacttgaagatagaagaaaataacattaaaaatgcatccctggtt
caaattgatgcaattaatgaacagtcatcaccttcatcgtctatgattattgatgctcat
ctctcaaatgctgttaatactcagcagtacaaagtcctcattggtaaccgggaatggatg
attagaaatggtcttgtcataagtaatgatgtggacgagtctatgattgaacatgaaaga
agaggccggactgctgtgttggtgacaatcgatgatgaactgtgtggcttgatcgctatt
gctgatactgtgaaacctgaggcagagctggctgtgcacattctgaaatctatgggtttg
gaagtagttctgatgactggagacaacagtaaaacagctcggtctattgcttctcaggtt
ggcattactaaggtgtttgctgaagttctgccttcccacaaagttgctaaggtgaagcag
cttcaggaggagggaaagcgcgtagccatggtaggagatggaatcaatgactctccagct
ctggcaatggcaagcgtcggaattgccatcggcacaggcacagatgtagccatcgaagca
gctgacgtggttttgataaggaatgaccttctggatgttgtggcaagtattgacttgtca
aggaaaacagtcaagaggattcgaatcaattttgtctttgctctgatttataatctgatt
ggaattcccatcgctgctggagtttttctgcccatcggcttggttttacaaccctggatg
ggatccgcagccatggccgcttcatctgtctctgtggtactttcttcccttttcctcaag
ctttacaggaagccaacatatgacaattatgagttgcgtccccggagccacacaggacag
aggagtccttcagaaatcagcgttcacgttggaatagatgatacctccagaaattctcca
agactgggtttactggaccggattgtcaattacagcagagcctccataaattcactgctg
tctgacaaacgctccctcaacagcgtcgtcactagtgagcctgataagcactcacttctg
gtgggagacttccgggaagatgacgacaccacactgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (26)   
   RefSeq(nuc) (6)   
   GenBank (10)   
   EMBL (10)   
Protein domain (7)   
   Pfam (7)   
All databases (55)   

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