KEGG   Rattus norvegicus (rat): 25021
Entry
25021             CDS       T01003                                 
Symbol
Itgam
Name
(RefSeq) integrin alpha-M precursor
  KO
K06461  integrin alpha M
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04145  Phagosome
rno04514  Cell adhesion molecules
rno04610  Complement and coagulation cascades
rno04613  Neutrophil extracellular trap formation
rno04640  Hematopoietic cell lineage
rno04670  Leukocyte transendothelial migration
rno04810  Regulation of actin cytoskeleton
rno05133  Pertussis
rno05134  Legionellosis
rno05140  Leishmaniasis
rno05146  Amoebiasis
rno05150  Staphylococcus aureus infection
rno05152  Tuberculosis
rno05202  Transcriptional misregulation in cancer
rno05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    25021 (Itgam)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    25021 (Itgam)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    25021 (Itgam)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    25021 (Itgam)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    25021 (Itgam)
   04610 Complement and coagulation cascades
    25021 (Itgam)
   04613 Neutrophil extracellular trap formation
    25021 (Itgam)
   04670 Leukocyte transendothelial migration
    25021 (Itgam)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    25021 (Itgam)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    25021 (Itgam)
  09171 Infectious disease: bacterial
   05133 Pertussis
    25021 (Itgam)
   05134 Legionellosis
    25021 (Itgam)
   05150 Staphylococcus aureus infection
    25021 (Itgam)
   05152 Tuberculosis
    25021 (Itgam)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    25021 (Itgam)
   05140 Leishmaniasis
    25021 (Itgam)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25021 (Itgam)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    25021 (Itgam)
   04515 Cell adhesion molecules [BR:rno04515]
    25021 (Itgam)
   04090 CD molecules [BR:rno04090]
    25021 (Itgam)
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    25021 (Itgam)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    25021 (Itgam)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   25021 (Itgam)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   25021 (Itgam)
CD molecules [BR:rno04090]
 Proteins
  25021 (Itgam)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Adhesion molecules of cell surface
   25021 (Itgam)
SSDB
Motif
Pfam: ITGAX-like_Ig_3 VWA FG-GAP Integrin_A_Ig_2 VWA_2 Integrin_A_Ig_1 Integrin_alpha FG-GAP_3 FG-GAP_2 Integrin_A_Ig_3 DUF3660
Other DBs
NCBI-GeneID: 25021
NCBI-ProteinID: NP_036843
RGD: 2926
Ensembl: ENSRNOG00000019728
UniProt: Q9JI30
Position
1:192089496..192139947
AA seq 1151 aa
MTLKFLLVTVLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQT
GALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVN
GLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQF
QKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQ
KINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRREL
DTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAIT
SNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLV
LGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAP
HHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAI
GAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMD
LAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKN
TKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPD
CVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDL
SITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSK
KPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVV
TSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLG
QRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLN
CSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFAL
LPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMM
NEAAPQDGPPQ
NT seq 3456 nt   +upstreamnt  +downstreamnt
atgactcttaaatttcttctggtgacagtcctaaccttgtgtcatggcttcaatttggac
actgaaaatcccatgaccttccaagagaatgcaagaggcttcgggcagagtgtgatccag
cttggtgaaacccgagtggttgttgcagccccccaggaggtaaaggcggttaaccagaca
ggtgccctctaccagtgtgactacagcacaaaccggtgcgaccccattcccctgcaagta
cctccagaggctgtgaatatgtccttgggcctgtccctggctgctactaccgtccctcca
cagctgctggcttgtggccccacagtacaccagaactgcaaggagaacacttacgtcaat
ggattgtgctacctattcggctccaacctgctgaggaagccccagcagttcccagaggct
ctcagaggatgtcctcagcaggagagcgacattgccttcttgattgacggctccggtagc
atcaacagcatcgactttcagaagatgaaggaatttgtctcaactgtgatggaccagttc
caaaagtctaaaaccttgttctctttgatgcagtactctgatgaattccggactcacttc
accttcaatgatttcaagagaaaccctgacccaaaatcacatgtgagacccataaggcag
ctgaatggaaggacaaaaactgcctcagggatccgtaaagtagtgagagaactgtttcag
aaaatcaatggggcccgggacaatgccgcgaagatcctagttgtcatcacagacggagaa
aagtttggtgaccccctaaattatgaggatgtcattcctgaggcagaggaagcagggatc
attcgctacgttattggggtgggaaacgccttccacaaaccacagtcccgcagagagctt
gacaccatcgcgtctaagccagctggtgatcacgtgttccaagtggacaactttgaagct
ctgaataccattcggaaccagctccaggaaaagatctttgcaattgagggcacccagaca
ggaagtaccagctcctttgagcatgagatgtctcaagaaggctttagcgctgccattacc
tctaacggtcccttgctgggctccgtggggagctttgactgggcaggtggagccttcctg
tatccatcaaaggataaagccactttcatcaacacaaccagaatagattcagacatgaac
gatgcttacttgggttatgcttctgcagtcatctcgaggaaccgcgtccaaagcttggtt
ttaggggcacctcgatatcagcatatcggcctggtggtgatgttcaagcagaatttcggt
gcctgggagccccacactgatatcaagggcagccagatcggctcttattttggggcctcc
ctctgttctgtggacatggacgctgatggcaataccaacttgatcctcattggggcccct
catcactatgagaagacccgagggggccaggtgtcagtgtgccccttgcctagggggaga
gcacggtggcagtgtgaagctattctccatggcgatcagggccatccatggggtcgcttt
ggggcagcattgacagtgctgggagatgtgaatggagacaaactgacagatgtggccatt
ggggccccaggagagcaggagaatcagggtgctgtctacatttttcatggagcatcagta
gccagcatcagtacccctcacagccagcggatcgcaggcgcccgcttctcccccgggctc
cagtactttgggcagtctctgagtgggggcaaggatctcacaatggacggcctgatggac
ttggctgtgggggcgcaggggcgtcttctgctgatcagagcccagcctgtgctgagactg
gaggcaaccatggaattcagccccaagaatctagcaaggagtgtgtttgcgtgtcaagaa
gaagtagtcaaaaacaaggatgctggggaggtcagagtctgcctccatgtccgcaagaac
accaaggacaggctgcgagaaggagacatccagagcactgtcacttatgacctggcttta
gaccccggccgctcagttgtccgagccttctttgatgaaacaaagaacggcatactcagg
cgcatccgggtctttggattgacacagaaatgtgaaaccctgaagctaattttaccggac
tgtgtggacaactcagtgagtcccatcatcctgcgccttaattacacactggttggggag
cccttgcggtcctctagggaccttcggccagttctggctatggaggctcagaggatcttc
acagctatgtttccctttgagaagaattgtggcaatgacaccatttgccaggatgatctc
agcatcaccgtgagttccatacgcgtgaacactttggtggtgggagactcccgggacttt
gacgtgagtgtgactctgagaaatgatggcgaggattcctatgggaccaaggttacctgt
tattacccatctggcttgtcttaccggaaggtgtcagcaagccagaaccagttctccaag
aagccttggcgtgtgatagctgagcccagttcttctgaagggcaaggggttctgaagagc
accatctgggatataaaccatcccatctttcccgctaattctgaggtcacgtttaatgtc
acatttgatgtggactctgatgcctcccttgggaacaaactgctcctcaaggtcgttgtg
accagcgagaacaacgtgtccaggaccgacaaaactgagtctcagttggagctgcctgtg
aagtacgccatctacatggtcgtcaccagtggtgagagttctatcaaatatctcaacttc
acagcttcagagatgaccagtaaggtcatacagcatcagtaccagttcaacaacctgggc
cagaggagcttccctgtcagcgtggtcttctggatccctgtccagatcaacaaggtgacc
atatgggatcctccccaggtcaccttctcccagaacctctcaagtgtctgtcgcactgag
cagaaatccccctctcactccaagttccaggatgagcttgaaaggaccccagtgctgaac
tgctctgttgcagtctgcaagagaatccagtgtgacatcccttccttcaacagtaaagaa
atattcaacgtcaccctccagggcaatctgctatttgactggtacatcgagacttctcac
gaccacctcctgcttgtgagcactgccgagatcctctttaacgactccgcatttgcccta
cttccggggcaggagacgtttgtgaaggctcagacagagaccaaagtggagccatataaa
gttcacaaccctgtaccactcattgtgggcagctccgtcggaggcctggtgctcttggct
ctcatcactgctggcctgtacaagcttggctttttcaaacgacagtacaaggacatgatg
aatgaagccgctccccaagatggcccccctcagtaa

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (11)   
   Pfam (11)   
All databases (49)   

Download RDF
DBGET integrated database retrieval system