KEGG   Rattus norvegicus (rat): 25118
Entry
25118             CDS       T01003                                 
Symbol
Itga1
Name
(RefSeq) integrin alpha-1 precursor
  KO
K06480  integrin alpha 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04151  PI3K-Akt signaling pathway
rno04510  Focal adhesion
rno04512  ECM-receptor interaction
rno04640  Hematopoietic cell lineage
rno04810  Regulation of actin cytoskeleton
rno04820  Cytoskeleton in muscle cells
rno05165  Human papillomavirus infection
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    25118 (Itga1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    25118 (Itga1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    25118 (Itga1)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    25118 (Itga1)
   04810 Regulation of actin cytoskeleton
    25118 (Itga1)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    25118 (Itga1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    25118 (Itga1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    25118 (Itga1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    25118 (Itga1)
   05414 Dilated cardiomyopathy
    25118 (Itga1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    25118 (Itga1)
   04515 Cell adhesion molecules [BR:rno04515]
    25118 (Itga1)
   04090 CD molecules [BR:rno04090]
    25118 (Itga1)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   25118 (Itga1)
Cell adhesion molecules [BR:rno04515]
 Integrins
  Integrin alpha subunits
   25118 (Itga1)
CD molecules [BR:rno04090]
 Proteins
  25118 (Itga1)
SSDB
Motif
Pfam: VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_1 VWA_2 Integrin_A_Ig_3 FG-GAP_3 FG-GAP_2 DUF11 LYRIC Integrin_alpha Cation_ATPase_N
Other DBs
NCBI-GeneID: 25118
NCBI-ProteinID: NP_112256
RGD: 2923
Ensembl: ENSRNOG00000053550
UniProt: P18614 A6I5T3
Structure
Position
2:complement(48379181..48545336)
AA seq 1180 aa
MVPRRPASLEVTVACIWLLTVILGFCVSFNVDVKNSMSFSGPVEDMFGYTVQQYENEEGK
WVLIGSPLVGQPKARTGDVYKCPVGRERAMPCVKLDLPVNTSIPNVTEIKENMTFGSTLV
TNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSFAPVQECSTQLDIVIVLDGS
NSIYPWESVIAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAANKI
GRQGGLQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNYRLKQVIQDCEDE
NIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKALGERIF
ALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKANQMVIPHNTT
FQTEPAKMNEPLASYLGYTVNSATIPGDVLYIAGQPRYNHTGQVVIYKMEDGNINILQTL
GGEQIGSYFGSVLTTIDIDKDSYTDLLLVGAPMYMGTEKEEQGKVYVYAVNQTRFEYQMS
LEPIRQTCCSSLKDNSCTKENKNEPCGARFGTAIAAVKDLNVDGFNDVVIGAPLEDDHAG
AVYIYHGSGKTIREAYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAAL
FWARDVAVVKVTMNFEPNKVNIQKKNCRVEGKETVCINATMCFHVKLKSKEDSIYEADLQ
YRVTLDSLRQISRSFFSGTQERKIQRNITVRESECIRHSFYMLDKHDFQDSVRVTLDFNL
TDPENGPVLDDALPNSVHEHIPFAKDCGNKERCISDLTLNVSTTEKSLLIVKSQHDKFNV
SLTVKNKGDSAYNTRTVVQHSPNLIFSGIEEIQKDSCESNQNITCRVGYPFLRAGETVTF
KIIFQFNTSHLSENAIIHLSATSDSEEPLESLNDNEVNISIPVKYEVGLQFYSSASEHHI
SVAANETIPEFINSTEDIGNEINVFYTIRKRGHFPMPELQLSISFPNLTADGYPVLYPIG
WSSSDNVNCRPRSLEDPFGINSGKKMTISKSEVLKRGTIQDCSSTCGVATITCSLLPSDL
SQVNVSLLLWKPTFIRAHFSSLNLTLRGELKSENSSLTLSSSNRKRELAIQISKDGLPGR
VPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK
NT seq 3543 nt   +upstreamnt  +downstreamnt
atggtccccaggcgtcctgccagcctagaggtcactgtagcctgcatatggcttctcacg
gtcatcctaggcttctgcgtctccttcaatgttgatgtgaaaaactcaatgagtttcagt
ggcccagtagaggacatgtttggatacactgttcaacaatatgaaaacgaagaaggcaaa
tgggttcttattggttctcctttagttggccaacccaaagcaagaactggagatgtctat
aagtgtccggttgggagagagagagcaatgccttgcgtgaagttggacttgccagttaac
acatcgatccccaatgtcacagaaataaaggaaaacatgacatttggatcaactttagtc
accaacccgaatggaggatttctggcatgtgggcccttgtatgcctatagatgtggacat
ttgcattatacaactggaatatgttctgatgtcagtcctacatttcaagttgtgaactcc
tttgcccctgtacaagaatgcagcacccagctggacatagtcatcgtcctggatggctcc
aacagcatctacccctgggaaagtgtcatcgcctttttaaacgaccttcttaagaggatg
gatattggccctaagcagacacaggtcgggattgtacagtatggagagaatgtaacccat
gagttcaacctcaataagtattcatccacagaagaggtccttgtcgcagcaaacaaaata
ggccgacagggaggcctccaaacgatgacagcccttggaatagacacagccaggaaagag
gcattcactgaagctcggggtgccaggaggggagttaaaaaagtcatggttattgtgacc
gacggagaatcgcatgacaactatcgcctgaaacaggtcatccaagactgcgaggacgaa
aacattcagcgattttccatagctatccttggccactataacagggggaacttaagcact
gaaaaatttgtggaggaaataaaatcgatcgcaagcgagcccacggaaaagcacttcttc
aatgtctcggatgagttggccctggtcactattgttaaagctctgggagaaaggatattc
gctttggaagcgacagctgaccagtcagcagcttcatttgagatggaaatgtctcagact
ggcttcagtgctcactactcccaggactgggtcatgcttggagcggtgggagcctatgac
tggaacggaactgtggtcatgcagaaggctaaccagatggtcatccctcataacaccacc
tttcaaactgagcccgccaagatgaacgagcctctggcttcttatttaggttacacagtg
aactcggccaccatccctggagatgtgctctacatcgctgggcagcctcggtacaatcat
acgggccaggtcgtcatctacaagatggaggatgggaacatcaacattctgcagacactc
ggcggagagcagattggttcctactttggtagtgtcttaacaacaattgacatcgacaaa
gattcttatactgatctgcttctcgtcggggcccccatgtacatggggacagagaaagag
gaacagggcaaggtgtacgtgtacgctgtgaatcagacaaggtttgaatatcaaatgagc
ctggaaccaattaggcagacctgctgctcatccctgaaggataattcatgcacgaaagaa
aacaagaatgagccctgcggggcccgcttcggaacagcaattgctgctgtaaaagacctc
aacgtggatggatttaatgacgtcgtgattggagctccgctggaagatgaccacgcagga
gctgtgtacatttatcatggcagtggcaagaccataagggaggcgtatgcacaacgcatt
ccatcaggtggggatggcaagaccctgaaatttttcggccagtctatccacggagagatg
gatttaaatggtgacggtctgactgacgtgaccattggaggccttggtggagcagccctc
ttctgggccagagatgtggctgtagttaaagtgaccatgaattttgaacccaataaagtg
aatattcaaaagaaaaactgccgtgtggagggcaaagaaacagtgtgcataaatgctaca
atgtgttttcatgtgaaattaaagtctaaagaggactcaatttacgaggctgatctgcag
taccgtgtcacccttgattcactgaggcagatatcacggagctttttttctggaactcag
gaaaggaagattcaaagaaatatcaccgttcgagaatcagaatgcatcaggcactccttc
tacatgttggacaaacatgactttcaggactctgtgagagtgactctggattttaatctc
actgatccagaaaatggtcctgtacttgatgacgctctgccaaactcagtccacgaacac
attccctttgccaaagactgtggaaacaaggaaagatgcatttcagacctcactctgaat
gtgtccaccacagaaaagagcctgctgatcgtcaagtcccagcatgacaagttcaacgtt
agcctcaccgtcaaaaacaaaggagacagtgcgtacaacaccaggacagtggtgcagcat
tcaccaaatctgattttttcgggaattgaggagatccaaaaagatagctgtgaatctaat
caaaatatcacttgcagagttggatatcctttcctaagagcaggagaaacggttaccttc
aaaataatattccagtttaacacatcccatctctcggaaaatgcaatcattcacttaagt
gcaacaagtgacagtgaggagcccctggaatctcttaatgataatgaagtaaatatttcc
atcccagtaaaatatgaagttggactgcagttttacagttctgcgagtgaacatcacatt
tcagtcgctgccaatgagacgatccctgagtttattaactccactgaggacattgggaat
gaaattaatgtcttctatacgattagaaagagggggcatttcccaatgccagaacttcag
ctgtcaatttcattccccaatttgacggcagatggttatcctgtactgtacccaattgga
tggtcatcttcagataatgtgaactgtagaccccggagccttgaggacccctttggcatc
aactctgggaagaaaatgacaatatcgaagtctgaggttctcaaaagaggcacaatccag
gactgcagtagtacgtgtggagttgccaccatcacgtgtagcctccttccttccgacctg
agtcaagtgaatgtctcgctcctcctgtggaaaccgactttcataagagcacatttttcc
agcttaaaccttactctaagaggagaacttaagagtgaaaattcatcgctgactttaagt
agcagcaaccggaagcgagagctggctattcagatatccaaagacgggctcccaggcaga
gtgccgctgtgggttatcctcctgagcgccttcgcggggctactgctgctaatgctcctt
atattggctctgtggaagattggattcttcaaaaggccactgaagaagaaaatggagaaa
tga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
3D Structure (3)   
   PDB (3)   
Protein domain (12)   
   Pfam (12)   
All databases (48)   

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