KEGG   Rattus norvegicus (rat): 25155
Entry
25155             CDS       T01003                                 
Symbol
Syk
Name
(RefSeq) tyrosine-protein kinase SYK
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04064  NF-kappa B signaling pathway
rno04072  Phospholipase D signaling pathway
rno04151  PI3K-Akt signaling pathway
rno04380  Osteoclast differentiation
rno04611  Platelet activation
rno04613  Neutrophil extracellular trap formation
rno04625  C-type lectin receptor signaling pathway
rno04650  Natural killer cell mediated cytotoxicity
rno04662  B cell receptor signaling pathway
rno04664  Fc epsilon RI signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno05152  Tuberculosis
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05168  Herpes simplex virus 1 infection
rno05169  Epstein-Barr virus infection
rno05171  Coronavirus disease - COVID-19
rno05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    25155 (Syk)
   04072 Phospholipase D signaling pathway
    25155 (Syk)
   04151 PI3K-Akt signaling pathway
    25155 (Syk)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    25155 (Syk)
   04613 Neutrophil extracellular trap formation
    25155 (Syk)
   04625 C-type lectin receptor signaling pathway
    25155 (Syk)
   04650 Natural killer cell mediated cytotoxicity
    25155 (Syk)
   04662 B cell receptor signaling pathway
    25155 (Syk)
   04664 Fc epsilon RI signaling pathway
    25155 (Syk)
   04666 Fc gamma R-mediated phagocytosis
    25155 (Syk)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    25155 (Syk)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    25155 (Syk)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    25155 (Syk)
   05168 Herpes simplex virus 1 infection
    25155 (Syk)
   05167 Kaposi sarcoma-associated herpesvirus infection
    25155 (Syk)
   05169 Epstein-Barr virus infection
    25155 (Syk)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    25155 (Syk)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    25155 (Syk)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     25155 (Syk)
Protein kinases [BR:rno01001]
 Non-receptor tyrosine kinases
  SYK family
   25155 (Syk)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1
Other DBs
NCBI-GeneID: 25155
NCBI-ProteinID: NP_036890
RGD: 3796
Ensembl: ENSRNOG00000012160
UniProt: Q64725
Position
17:complement(12756493..12830927)
AA seq 629 aa
MAGNAVDNANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA
HHYTIERELNGTYAISGGRAHASPADLCHYHSQEPEGLVCLLKKPFNRPPGVQPKTGPFE
DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQT
VLIGSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGVQMGHPGSSNAHPVTWSPGGIISRIKSYSFPKPGHKKP
PPPQGSRPESTVSFNPYEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLD
RKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQ
LDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLE
ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY
FKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYDLMN
LCWTYDVENRPGFAAVELRLRNYYYDVVN
NT seq 1890 nt   +upstreamnt  +downstreamnt
atggcgggcaatgctgtggacaatgccaaccacctgacctacttttttggcaacatcacc
cgggaagaggccgaagactacctggtccagggaggcatgaccgatgggctctacctgcta
cgccagagccgcaattacctgggtggttttgctttgtcggtggcacacaacaggaaggca
caccactacactatcgagagagaacttaacggcacctacgccatctccgggggcagggcc
catgccagcccggcagacctctgccattaccactcccaggaacccgaaggccttgtctgc
ctcctcaagaagcccttcaaccggcccccgggggtacagcccaagactggaccctttgag
gacctgaaggagaacctcatcagggaatatgtgaaacagacctggaaccttcagggccag
gctctggagcaagccatcatcagtcagaagccccaactggagaagttgatcgccacgacg
gctcatgagaagatgccctggttccatggcaacatctccagagacgagtcagagcagacg
gtcctcatagggtcaaagaccaacggaaaattcctgatcagggccagagacaacaacggc
tcctttgcactgtgcctgctgcacgaagggaaggtattacactatcgcatcgacagggac
aagaccgggaagctttccatccccgaggggaagaagtttgacaccctctggcagctagtg
gaacattactcttacaagccagatgggctattaagagtcctcacggtaccatgtcaaaag
attggcgtgcagatgggccacccaggaagttcaaatgcccatcctgtgacttggtcacca
ggtggaataatctcaagaatcaaatcctactccttcccaaagcctggccacaaaaagcct
cccccaccccaagggagccgtccggagagcaccgtgtccttcaatccctatgagccaacg
ggaggggcctggggcccagacagaggccttcagagagaagccctgcccatggacactgag
gtatatgagagtccttacgctgaccctgaagagatccggcccaaagaggtctacctggac
aggaaactgctgaccctggaggacaatgaactgggctctggcaacttcgggactgtgaaa
aagggatactaccaaatgaaaaaagttgtaaaaacagtggctgtgaaaatcctgaagaat
gaggccaacgacccggctctgaaggacgagctgctggcggaggccaacgtcatgcagcag
ctggacaacccctacattgtgcgcatgatcggaatctgtgaggcggagtcgtggatgctg
gtgatggagatggcggagctggggcccctcaacaagtacctgcagcagaacaggcacatc
aaggataagaacatcatcgagctggttcaccaggtttccatgggaatgaagtatttggag
gagagcaattttgtgcacagagatctggccgcgaggaacgtgcttctggtcacccagcac
tacgccaagatcagtgacttcggtctttccaaagccctccgtgctgatgaaaactactac
aaggcccagacccacgggaagtggccggtgaagtggtacgcccccgaatgcatcaactac
tttaagttctccagtaagagtgatgtctggagcttcggagtcctgatgtgggaagcgttc
tcctacgggcagaagccatacagagggatgaaagggagcgaagtgactgccatgctggag
aaaggagagcggatggggtgccctccaggatgcccgagagagatgtacgacttgatgaac
ctatgctggacttacgatgtggagaacaggccaggattcgcggctgtggaactgcggctt
cgcaattactactacgacgtggttaactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
Protein domain (5)   
   Pfam (5)   
All databases (51)   

Download RDF
DBGET integrated database retrieval system