KEGG   Rattus norvegicus (rat): 25225
Entry
25225             CDS       T01003                                 
Symbol
Uba1y
Name
(RefSeq) ubiquitin-activating enzyme, Chr Y
  KO
K03178  ubiquitin-activating enzyme E1 [EC:6.2.1.45]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04120  Ubiquitin mediated proteolysis
rno05012  Parkinson disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    25225 (Uba1y)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    25225 (Uba1y)
   05022 Pathways of neurodegeneration - multiple diseases
    25225 (Uba1y)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:rno04121]
    25225 (Uba1y)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    25225 (Uba1y)
Enzymes [BR:rno01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.45  E1 ubiquitin-activating enzyme
     25225 (Uba1y)
Ubiquitin system [BR:rno04121]
 Ubiquitin-activating enzymes (E1)
  Ubiquitin activating enzyme
   25225 (Uba1y)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   25225 (Uba1y)
  Exosomal proteins of other body fluids (saliva and urine)
   25225 (Uba1y)
  Exosomal proteins of colorectal cancer cells
   25225 (Uba1y)
SSDB
Motif
Pfam: UBA_E1_SCCH ThiF E1_UFD E1_FCCH E1_4HB BCDHK_Adom3
Other DBs
NCBI-GeneID: 25225
NCBI-ProteinID: NP_001395667
RGD: 3925
Ensembl: ENSRNOG00000063279
Vega: OTTRNOG00000002372
Position
Y:481352..504038
AA seq 1057 aa
MSSSVLSKKRRVSGPDSEVDSSWPSTHSVMFGAPPGPNSGMSKNKEMDIDESLYSRQLYV
LGHEAMKHLQTSSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLHEE
DIGKNRAEVSQPRLAELNSYVPVHTYTGPLVDDFLSGFQVVVLTNTPLEYQLQVGEFCHS
HGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLSAMVSMITKENPGIVTCLEETRHG
FESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFSICDTSSFSEYTRGGIVSQVKVSQKI
SFKSLVASLAEPEFVITDFAKCCRPAQLHIGFQALHQFCTQHSRPPRPHNEEDAAEMVTL
AQAVNAQSLPAVQQDCLDIDLIRKLAYVAAGDLAPMSAFIGGLAAQEVMKACSGKFMPIR
QWLYFDALECLPEHRVAFMEDKCLPRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGC
ELLKNFAMIGLGCGEGGEITVTDMDTIEKSNLNRQFLFRPWDVTKLKSETAAAAVRDINP
HIRVCSHQNRVGPETEHVYDDDFFQNLDGVANALDNVDARLYMDRRCVYYRKPLLESGTL
GTKGNVQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQSAE
NVNQYLMDPKFMERTLQLAGTQPLEVLEAIQCSLVLQRPQTWADCVTWAYQHWHTQYSHN
IQQLLHNFPPDQLTSSGVLFWSGPKRCPHPLTFDTNNPLHLDYVMAAANLFAQTYGLEGS
QDCAAVTTLLQSLPAPKFAPKSGIRIHVSEQELQSTSATVDDSHLEELKTSLPTPDKMLG
FKMHPIDFEKDDDSNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTSAV
VGLVCLELYKVVQGHQQLDSFKNSFINLALPFFSFSAPLAPGYHQYYDKKWTLWDRFDVQ
GLQPSGEEMTLKQFLDYFKTEHKLEITILSQGVSMLYSFFMPATKLQERLDQPMTEIVSR
VSKRKLGQHVKSLVFELCCNNESGDDIEVPYVRYIIG
NT seq 3174 nt   +upstreamnt  +downstreamnt
atgtccagctcggtcctgtccaagaaacgcagagtgtctggacctgactctgaggtggat
tctagttggccttctacccattctgtgatgtttggcgcacccccagggccaaacagcgga
atgtcaaaaaacaaggaaatggatatagatgaaagcctttactcccgccagctgtatgta
ctaggtcatgaggcaatgaaacatctccagacgtccagtgtactgatatcaggcctgcag
ggtctgggtgtggaaattgccaagaatatcatccttggtggggtcaaggctgtcactctc
catgaccagggcactgcccagtgggctgatctgtcttcccagttctacctgcatgaggaa
gatattggcaaaaatcgagctgaggtatcccaaccacgccttgctgaactcaacagttat
gttcctgtgcacacttacactggacctctagttgacgacttccttagtggttttcaggtg
gtggttcttaccaacactcctttggaatatcagctgcaggtgggtgaattctgccatagc
catggaatcaagctggtagtagcagacactcggggcctagttggacaactcttctgtgac
tttggagaggaaatgattctcactgatgcaaatggagaacagccactcagtgctatggtt
tcaatgatcactaaggagaatccagggattgtcacctgcttggaggaaacccggcatgga
tttgaaagtggtgactttgtctctttcacagaagttcaaggcatgagtgaactgaatggc
attggtcctatggagatcaaagttctgggtccctattcctttagtatctgtgatacctcc
agcttctctgagtacacccgtggaggcattgtcagtcaagtgaaagtatctcagaagatc
agttttaaatccctagttgcctcgctggcagagccagagtttgtgataacagattttgct
aagtgctgtcgccctgctcagctccacattggcttccaggccctgcatcagttctgtact
cagcacagcaggcctcctcggccccataatgaggaggatgctgcagaaatggtgacctta
gcacaggctgtgaatgctcaatctttgccagcagtccagcaggattgcctagatatagac
ctcatccggaagttggcctatgtagcagctggggatctggcacccatgagtgctttcatt
ggtggtttggctgcccaggaggtcatgaaggcttgttctggaaagtttatgcctattagg
cagtggctgtactttgatgccctcgaatgtctcccggagcacagagtggccttcatggaa
gataagtgcctgccgcgccagaaccgttacgatgggcaagtggcggtatttggatcagac
ctacaagagaagcttggcaagcagaagtacttcctggtaggtgcaggtgccattggttgt
gagctgctcaagaactttgccatgattggccttggctgtggagagggtggagaaatcaca
gttacagacatggacaccattgagaagtcaaacctgaacagacagtttctctttcgcccc
tgggatgtcacaaaattaaagtctgagactgctgctgcagcagtacgtgacataaatcca
cacatcagggtgtgcagccaccagaatcgagtaggccctgagacagaacacgtctatgat
gatgacttcttccaaaacctggatggtgtggccaatgctctagacaatgtggatgctcga
ttatacatggaccgccgttgtgtttactatcgtaagcctctgctggaatccggcacattg
ggcaccaagggcaacgtgcaagtggttgttcccttcttgacagaatcttacagctctagc
caggacccacctgagaaatccatccccatctgcacactgaagaacttccccaatgccatt
gagcataccctgcagtgggctcgggatgagtttgaaggactgttcaagcagtcagccgaa
aatgttaaccaatacctcatggaccccaagttcatggagcggacactgcagctagctggc
acccagcctttggaagtactggaggctatacagtgcagcctggtcctgcagaggccacag
acttgggccgactgtgtgacttgggcctaccagcactggcacacccagtattctcacaac
atccagcagttgctgcacaacttccctccagaccagcttacaagctctggggtacttttt
tggtcaggacctaaacgctgtccacatccactcacctttgacacaaacaatcccctacat
ctggattatgttatggctgctgccaacctgtttgctcagacatacggactagaagggtcc
caggactgtgctgctgtgaccacactcctgcagtctctgccagcccccaagtttgctccc
aagtctggcatcaggatccatgtttctgaacaggagctgcagagtaccagtgccacagtc
gatgacagccacctagaggaactcaagacttcactacctactccagacaagatgcttgga
ttcaagatgcatcccattgatttcgagaaggatgatgacagcaactttcacatggatttc
attgtggcagcatccaacctccgggcagaaaactatgacattccccctgcagaccggcat
aagagcaaactgattgcagggaagatcatcccagctattgcaaccactacatcagctgta
gttggcctcgtgtgtctggagctgtataaggtggttcagggtcaccaacaactggattct
tttaaaaacagttttatcaacttggctctgcctttcttcagcttctctgcacctctagct
ccagggtatcaccagtactatgataaaaagtggacattgtgggatcgttttgatgtgcag
ggactgcaacctagtggtgaagagatgaccctcaagcagtttctagactactttaagaca
gagcacaagctggaaatcaccatactatcccagggtgtgtccatgctctattccttcttt
atgccagccaccaaactccaggaacggttggatcagccgatgacagagattgtgagccgt
gtgtcaaagcggaaactgggccagcacgtgaagtcccttgtgtttgagctgtgctgcaac
aatgagagtggagacgacattgaagttccttatgtacgatacatcatcggctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   Pfam (6)   
All databases (29)   

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