KEGG   Rattus norvegicus (rat): 25279
Entry
25279             CDS       T01003                                 
Symbol
Cyp24a1
Name
(RefSeq) 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial precursor
  KO
K07436  vitamin D3 24-hydroxylase [EC:1.14.15.16]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00100  Steroid biosynthesis
rno01100  Metabolic pathways
rno04928  Parathyroid hormone synthesis, secretion and action
rno05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    25279 (Cyp24a1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    25279 (Cyp24a1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    25279 (Cyp24a1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    25279 (Cyp24a1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.16  vitamin D3 24-hydroxylase
     25279 (Cyp24a1)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP24 family
   25279 (Cyp24a1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 25279
NCBI-ProteinID: NP_963966
RGD: 2462
Ensembl: ENSRNOG00000013062
UniProt: Q09128 A6JXS6
Structure
Position
3:complement(179694647..179709083)
AA seq 514 aa
MSCPIDKRRTLIAFLRRLRDLGQPPRSVTSKASASRAPKEVPLCPLMTDGETRNVTSLPG
PTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYR
TESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKIN
EVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLLQKETEEEALTFIT
AIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRLQRYSQQPGAD
FLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVL
PDNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYALPKGTVLTLNTQ
VLGSSEDNFEDSHKFRPERWLQKEKKINPFAHLPFGIGKRMCIGRRLAELQLHLALCWII
QKYDIVATDNEPVEMLHLGILVPSRELPIAFRPR
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgagctgccccattgacaaacggcgcaccctgatcgcttttctgcgccgactgcgcgac
ctgggacagcccccaaggtcggtgacatccaaggcgagcgcttcccgcgctccaaaagag
gtgcccctctgcccgctgatgacagacggtgagactcgaaacgtcacctccttgcctggg
cccaccaactggccactgctagggagtctactggagattttttggaaaggtggcctgaag
aaacagcacgacacgctggcagagtaccacaagaagtatggccagattttccggatgaag
ctgggctccttcgactccgtgcatctgggctcgccgagcctgctggaagctctgtaccgc
acagagagcgcgcatccccagcgactggagatcaaaccttggaaagcctatcgcgaccac
aggaacgaagcctacgggttgatgatcctggaaggacaggagtggcaaagggtccgcagc
gccttccagaagaaactcatgaagcccgtggagatcatgaagctggacaagaaaatcaat
gaggtcttggctgactttctagagcgcatggatgagctgtgcgatgagcgaggccgcatc
ccagacctgtacagtgagctgaacaagtggtcctttgaaagcatctgccttgtgttatat
gagaagagatttgggctccttcaaaaggagacagaagaagaagcgctgaccttcattacg
gccatcaaaacgatgatgagcacgtttgggaagatgatggtgacccccgtggagttgcac
aagcgcctcaacaccaaagtgtggcaggcacatacgctggcttgggacaccattttcaaa
tcagtcaaaccctgcatcgacaaccgcctacagagatattcccagcagcccggggcagat
ttcctctgtgatatttatcagcaagatcacctttccaagaaggaactgtacgccgctgtc
acggagctgcagctcgctgcagtggagacgaccgcgaacagcttgatgtggattctctac
aatctatcccggaatcctcaagcgcaacggagactccttcaggaagttcagagcgtgctg
cctgacaatcagacgccacgggcggaagacctgaggaatatgccctatttaaaggcctgt
ctgaaagaatccatgaggcttaccccaagtgtgccatttacaactcggacccttgacaaa
ccaacggttctgggtgaatacgctctacccaaaggaacagtgttaaccctcaatacccaa
gtgctgggttctagtgaagacaattttgaagattctcataagttcagacccgaacgctgg
cttcaaaaggagaaaaagatcaaccccttcgctcatctcccattcggcatcgggaagaga
atgtgcatcgggcgccggctggctgagttacagctccacctggctctctgctggataatc
caaaaatacgacattgtggccacagacaatgaacctgtggagatgctgcaccttggcatc
ctggtacccagccgggagctgccaattgcgttccgtccacggtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (36)   

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