KEGG   Rattus norvegicus (rat): 25388
Entry
25388             CDS       T01003                                 
Symbol
Arrb2
Name
(RefSeq) beta-arrestin-2
  KO
K04439  beta-arrestin
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04062  Chemokine signaling pathway
rno04144  Endocytosis
rno04340  Hedgehog signaling pathway
rno04728  Dopaminergic synapse
rno04740  Olfactory transduction
rno04926  Relaxin signaling pathway
rno04928  Parathyroid hormone synthesis, secretion and action
rno04929  GnRH secretion
rno05032  Morphine addiction
rno05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25388 (Arrb2)
   04340 Hedgehog signaling pathway
    25388 (Arrb2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    25388 (Arrb2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    25388 (Arrb2)
  09152 Endocrine system
   04929 GnRH secretion
    25388 (Arrb2)
   04926 Relaxin signaling pathway
    25388 (Arrb2)
   04928 Parathyroid hormone synthesis, secretion and action
    25388 (Arrb2)
  09156 Nervous system
   04728 Dopaminergic synapse
    25388 (Arrb2)
  09157 Sensory system
   04740 Olfactory transduction
    25388 (Arrb2)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    25388 (Arrb2)
  09165 Substance dependence
   05032 Morphine addiction
    25388 (Arrb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25388 (Arrb2)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   GPCR adaptor proteins
    25388 (Arrb2)
SSDB
Motif
Pfam: Arrestin_N Arrestin_C
Other DBs
NCBI-GeneID: 25388
NCBI-ProteinID: NP_037043
RGD: 2157
Ensembl: ENSRNOG00000019308
UniProt: P29067 A6HG47
Structure
Position
10:55645539..55653485
AA seq 410 aa
MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC
AFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTI
PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPG
PQPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQY
ADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDT
NLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHITLPRPQ
SAPREIDIPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDCDDQFC
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgggtgaaaaacccgggaccagggtcttcaagaagtcgagccctaactgcaagctcacc
gtgtacttgggcaagcgtgactttgtggatcacttggacaaagtggatcctgtcgatggt
gtggtgcttgtggatcctgactacttgaaggaccggaaagtgtttgtgaccctcacctgt
gccttccgctatggccgagaagacctggatgtactgggcctgtctttccgcaaagatctg
ttcatcgccacctaccaggccttcccccccatgcccaacccacctcggccccccacccgc
ctacaggaccgactgctgaagaagttgggccagcatgcccaccccttttttttcacaata
ccccagaatttgccttgctccgtcacactgcagccaggaccggaggacacagggaaggcc
tgtggagtagactttgagattcgagccttctgtgccaaatctatagaagaaaaaagccac
aaaaggaactccgtgcggcttatcatcagaaaggtacagtttgctcctgagacacccggc
ccccagccatcagctgaaaccacacgccacttcctcatgtctgaccggaggtccctgcac
ctagaggcttccctggacaaagagctgtactaccatggggaacccctcaatgtcaacgtc
cacgtcaccaacaattctgccaagaccgtcaagaagatcagagtgtctgtgagacagtat
gccgacatttgcctcttcagcaccgcgcagtacaagtgtcctgtggctcagcttgaacaa
gatgaccaggtgtctcccagttccacattctgcaaggtgtacaccataaccccgctgctc
agtgacaaccgagagaagcgtggccttgcccttgatgggcaactcaagcacgaagacacc
aacctggcttccagcaccattgtgaaggagggagccaacaaggaggtgctgggaatccta
gtatcctacagggtcaaggtgaagctggtggtgtctcgaggcggggatgtctccgtggag
ctacctttcgtcctaatgcaccccaagccccacgaccacatcacccttccccgaccccag
tcagccccccgggaaatagacatccctgtggataccaacctcattgaattcgataccaac
tatgccacagacgacgacatcgtgtttgaggactttgcgaggcttcggctgaaggggatg
aaggatgacgactgtgatgaccagttctgctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (12)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (15)   
   RefSeq(nuc) (11)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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