KEGG   Rattus norvegicus (rat): 25399
Entry
25399             CDS       T01003                                 
Symbol
Cacna2d1
Name
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 precursor
  KO
K04858  voltage-dependent calcium channel alpha-2/delta-1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04921  Oxytocin signaling pathway
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25399 (Cacna2d1)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    25399 (Cacna2d1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    25399 (Cacna2d1)
   04261 Adrenergic signaling in cardiomyocytes
    25399 (Cacna2d1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    25399 (Cacna2d1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    25399 (Cacna2d1)
   05414 Dilated cardiomyopathy
    25399 (Cacna2d1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    25399 (Cacna2d1)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   25399 (Cacna2d1)
SSDB
Motif
Pfam: VGCC_alpha2 VWA_N VWA VWA_3 VWA_2 dCache_1 IFN-gamma
Other DBs
NCBI-GeneID: 25399
NCBI-ProteinID: NP_001104317
RGD: 2247
Ensembl: ENSRNOG00000033531
UniProt: Q8VHS9
Position
4:complement(19902324..20330287)
AA seq 1079 aa
MAAGCLLALTLTLFQSWLIGPSSEEPFPSPVTIKSWVDKMQEDLVTLAKTASGVTQLADI
YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAMEAEKVQAAHQWREDFASN
EVVYYNAKDDLDPERNESESGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL
NELNWTSALDEVFKRNRDEDPTLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
FTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNVTGQSENKTNLK
NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKEPVTLDFLDA
ELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLP
TYSFYYIKAKIEETITQARYSETLKPDNFEESGYTFIAPREYCNDLKPSDNNTEFLLNFN
EFIDRKTPNNPSCNTDLINRILLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVY
PKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVELYIQG
KLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANH
DDYTNQIGRFFGEIDPSMMRHLVNISLYAFNKSYDYQSVCDPGAAPKQGAGHRSAYVPSI
TDILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSKQSCITEQTQYFFK
NDTKSFSGLLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLMQAEQTSDGPDPC
DMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIFGLQFILLWLVSGSRHYLW
NT seq 3240 nt   +upstreamnt  +downstreamnt
atggctgctggctgcctgctggccttgactctgacacttttccaatcttggctgatcggc
ccctcgagcgaggagcccttcccttcgcccgtcactatcaagtcatgggtggataaaatg
caggaagaccttgtcacactggcaaagacagcaagtggagtgactcagcttgctgacatt
tatgaaaaataccaagatttgtatactgtggagccaaataatgcacgccaactggttgaa
attgcagctagagacattgagaaacttctgagcaacagatctaaagccctggtgcgcctg
gctatggaagcagagaaagtccaagccgcccaccaatggagggaagattttgcaagcaac
gaagttgtctactacaacgctaaagacgatcttgatcctgaaagaaatgagagtgagtca
ggcagccaacggattaaacctgttttcatcgaagacgctaattttggacgccagatatcc
tatcaacatgcagcggtccatattcccacggacatctatgagggctcaaccatagtgtta
aacgaactcaactggacaagtgccttagatgaagttttcaaaagaaatcgagatgaagac
cctacattgctgtggcaagtgtttggcagcgccaccggcctggcccgatattatccagct
tctccgtgggtggataacagcagaactccaaacaagatcgatctctacgatgtacgcaga
agaccatggtacatccagggagctgcatcccccaaagacatgctcattctggtggacgtg
agtggaagtgtgagcggattgactctgaaactcatccggacatctgtctctgagatgtta
gaaaccctttccgatgatgatttcgtgaatgtagcttcatttaacagcaatgctcaggat
gtgagttgtttccagcacctggttcaagcgaatgtaaggaacaagaaggtgctgaaggat
gcggtgaataacatcacagcaaaggggataacagattacaagaaaggctttagcttcgcg
tttgaacagctacttaattataatgtttccagagccaattgtaataagatcatcatgtta
ttcacggatggaggagaagagagagcccaggagatatttgccaagtacaataaagacaaa
aaagtccgcgtgtttacattttctgttggtcaacataattatgacagaggacctattcag
tggatggcttgtgaaaacaaaggttattattatgagattccctctattggtgcaataaga
atcaatactcaggaatatctagatgttctgggaagaccaatggttttagccggggacaaa
gcaaagcaagtccagtggacaaatgtgtatttggatgctctggagctgggacttgtcatt
actggaactctaccggtcttcaacgtcactggccagtctgaaaataagactaacttgaag
aaccagttgattcttggtgtgatgggcgttgatgtgtctctggaagatattaagagattg
acaccacgttttacactgtgccccaacggttactattttgcaatcgatcctaatggttat
gtcttactgcatccaaatcttcagccaaaggagccggtcacactggattttctcgatgct
gagttagagaatgatattaaagtggagattcgaaataaaatgatagacggagaaagtgga
gaaaaaacattcagaactctggtcaaatctcaagatgagagatatattgacaaaggaaat
cgaacatacacatggacacctgtcaatggcacagattacagtttggccttggtattgcca
acctacagtttttactatataaaagccaaaatagaagagacaataactcaggccagatat
tcagaaaccctgaagccagacaattttgaagaatctggctacactttcatagcaccaagg
gaatactgcaatgacctgaaaccttcagataataacactgaatttcttttaaatttcaat
gaatttattgataggaaaactccaaacaacccttcctgtaatacagatttgattaataga
atcttgctggatgcgggttttacaaatgaacttgtccaaaattattggagtaaacagaaa
aatatcaaaggagtgaaggcacgctttgtggtgactgatggcggaattacaagagtttac
cccaaagaggctggagaaaactggcaagagaacccagagacgtatgaggacagcttctac
aaacggagcctagataacgataactacgttttcactgcgccctacttcaacaaaagtgga
cctggtgcctatgaatctggaattatggtaagcaaagctgtagaactgtacatccaagga
aaacttcttaagcctgcagttgtgggaattaaaattgacgtaaactcctggatagaaaat
tttaccaaaacttcaatcagggatccgtgtgctggtccagtttgtgactgcaaaagaaac
agtgatgtaatggactgtgtcattctagatgatggtggatttcttctgatggccaatcat
gatgattacactaatcagattggacgtttttttggagagattgacccgagcatgatgaga
cacctggttaatatatcactttatgcattcaataaatcatatgactatcagtctgtgtgt
gatccaggggcagcaccaaagcaaggagcaggacatcgctcagcctatgtgccatcaatt
acagacatactccagattggctggtgggccactgctgccgcctggtcaattctccagcag
ctactcttgagtttgacatttccacggctccttgaggcagttgaaatggaagaggatgac
ttcacagcttccctgtctaagcagagctgcatcacagaacaaactcagtacttcttcaag
aacgatactaaatcattcagtggtttactggactgtggaaactgttccaggatctttcat
gttgagaagcttatgaacaccaacctagtgttcataatggtggagagcaagggaacatgt
ccgtgtgacacgcggctgctcatgcaagcagaacagacttctgatggtccagatccttgc
gacatggttaagcagcccagataccgaaaaggacctgatgtctgctttgataacaatgtg
ctggaggattataccgactgtggtggtgtttctggattaaacccttccttatggtctatc
tttggactccaatttatactcctttggctggtatctggcagcagacactatctatggtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (12)   
   UniProt (1)   
   RefSeq(pep) (11)   
DNA sequence (21)   
   RefSeq(nuc) (11)   
   GenBank (5)   
   EMBL (5)   
Protein domain (7)   
   Pfam (7)   
All databases (56)   

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