KEGG   Rattus norvegicus (rat): 25423
Entry
25423             CDS       T01003                                 
Symbol
Ctsc
Name
(RefSeq) dipeptidyl peptidase 1 precursor
  KO
K01275  cathepsin C [EC:3.4.14.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04142  Lysosome
rno04210  Apoptosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    25423 (Ctsc)
  09143 Cell growth and death
   04210 Apoptosis
    25423 (Ctsc)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    25423 (Ctsc)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    25423 (Ctsc)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    25423 (Ctsc)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.14  Dipeptidyl-peptidases and tripeptidyl-peptidases
    3.4.14.1  dipeptidyl-peptidase I
     25423 (Ctsc)
Peptidases and inhibitors [BR:rno01002]
 Cysteine peptidases
  Family C1: papain family
   25423 (Ctsc)
Chaperones and folding catalysts [BR:rno03110]
 Intramolecular chaperones
  Papain family
   25423 (Ctsc)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   25423 (Ctsc)
SSDB
Motif
Pfam: Peptidase_C1 CathepsinC_exc Peptidase_C1_2 Pox_I6 Propeptide_C1
Other DBs
NCBI-GeneID: 25423
NCBI-ProteinID: NP_058793
RGD: 2445
Ensembl: ENSRNOG00000016496
UniProt: P80067 A6I5Z1
Structure
Position
1:151440860..151472430
AA seq 462 aa
MGPWTHSLRAALLLVLLGVCTVSSDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPT
EEKVVIHLKKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHE
TMTGWVHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINS
VQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVR
GINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGG
FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMK
LELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLD
YWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPIPKL
NT seq 1389 nt   +upstreamnt  +downstreamnt
atgggtccgtggacccactccttgcgcgccgccctgctgctggtgcttttgggagtctgc
accgtgagctccgacactcctgccaactgcacttaccctgacctgctgggtacctgggtt
ttccaggtgggccctagacatccccgaagtcacattaactgctcggtaatggaaccaaca
gaagaaaaggtagtgatacacctgaagaagttggatactgcctatgatgaagtgggcaat
tctgggtatttcaccctcatttacaaccaaggctttgagattgtgttgaatgactacaag
tggtttgcgtttttcaagtatgaagtcaaaggcagcagagccatcagttactgccatgag
accatgacagggtgggtccatgatgtcctgggccggaactgggcttgctttgttggcaag
aagatggcaaatcactctgagaaggtttatgtgaatgtggcacaccttggaggtctccag
gaaaaatattctgaaaggctctacagtcacaaccacaactttgtgaaggccatcaattct
gttcagaagtcttggactgcaaccacctatgaagaatatgagaaactgagcatacgagat
ttgataaggagaagtggccacagcggaaggatcctaaggcccaaacctgccccgataact
gatgaaatacagcaacaaattttaagtttgccagaatcttgggactggagaaacgtccgt
ggcatcaattttgttagccctgttcgaaaccaagaatcttgtggaagctgctactcattt
gcctctctgggtatgctagaagcaagaattcgtatattaaccaacaattctcagacccca
atcctgagtcctcaggaggttgtatcttgtagcccgtatgcccaaggttgtgatggtgga
ttcccatacctcattgcaggaaagtatgcccaagattttggggtggtggaagaaaactgc
tttccctacacagccacagatgctccatgcaaaccaaaggaaaactgcctccgttactat
tcttctgagtactactatgtgggtggtttctatggtggctgcaatgaagccctgatgaag
cttgagctggtcaaacacggacccatggcagttgcctttgaagtccacgatgacttcctg
cactaccacagtgggatctaccaccacactggactgagcgaccctttcaacccctttgag
ctgaccaatcatgctgttctgcttgtgggctatggaaaagatccagtcactgggttagac
tactggattgtcaagaacagctggggctctcaatggggtgagagtggctacttccggatc
cgcagaggaactgatgaatgtgcaattgagagtatagccatggcagccataccgattcct
aaattgtag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (32)   

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