KEGG   Rattus norvegicus (rat): 25427
Entry
25427             CDS       T01003                                 
Symbol
Cyp51
Name
(RefSeq) lanosterol 14-alpha demethylase
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00100  Steroid biosynthesis
rno01100  Metabolic pathways
Module
rno_M00101  Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    25427 (Cyp51)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rno00199]
    25427 (Cyp51)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     25427 (Cyp51)
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     25427 (Cyp51)
Cytochrome P450 [BR:rno00199]
 Cytochrome P450, animal type
  CYP51 family
   25427 (Cyp51)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 25427
NCBI-ProteinID: NP_037073
RGD: 2481
Ensembl: ENSRNOG00000007234
Vega: OTTRNOG00000000746
UniProt: Q64654 A6K271
Position
4:30991693..31010147
AA seq 503 aa
MVLLGLLQSGGSVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKS
PPYIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNS
KNEDLNAEEVYGRLTTPVFGKGVAYDVPNAVFLEQKKILKSGLNIAHFKQYVSIIEKEAK
EYFKSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWL
LPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDDE
IAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDL
NLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLD
FNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLINGYFP
SVNYTTMIHTPENPVIRYKRRSK
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggtactgctgggcttgctgcagtcaggcggctcggtgctcgggcaggcgatggagcag
gtgacaggaggcaacctgctttccacgctgctcatcgcctgcgccttcacgcttagcctt
gtctacctgttccgcctcgcagtgggccacatggtccagctgcccgctggagcgaaaagt
ccgccatatatttactctccaattccgttccttggccacgcgatagcatttgggaaaagt
ccaattgagttcctggaaaatgcatatgagaagtacggacctgtgtttagctttaccatg
gtgggcaagactttcacttaccttttggggagtgacgcagccgccctgctcttcaacagt
aagaacgaagacctgaatgcggaagaggtctacggtcggctgacaacgcccgtgtttggg
aagggagttgcatacgacgtgccaaatgcagttttcctggaacagaagaaaatactaaaa
agcggccttaacatagcccacttcaagcagtatgtttctatcattgaaaaagaagcgaag
gagtactttaaaagttggggagaaagcggagaaagaaatgtgtttgaagcgctgtctgag
ctcataattttaacagctagccattgcttacatggaaaggaaattagaagtcagctcaac
gagaaggtggctcagctgtacgcagacctggatggaggctttagccatgccgcctggctg
ttgccaggctggctgcccctgccgagtttcaggcgcagggacagagcccatcgagagatc
aagaatattttctacaaggccatccagaaacgtaggctgtcaaaagaaccagccgaggac
attcttcaaactttactggattctacatacaaggatgggcgtcctctgacggacgacgag
atcgcagggatgctcatcggactgctgctggccggacagcacacatcctccaccaccagt
gcctggatgggcttctttctggccagagataaaccacttcaagacaaatgctacttagaa
cagaaaacggtgtgcggggaggatctgcctcccttaacttatgagcagttgaaggatctg
aatttacttgatagatgcataaaagaaacactaagactgaggcctcctataatgaccatg
atgagaatggccaagacccctcagactgtggctgggtacaccattcctccaggacatcag
gtgtgtgtttctccaactgtcaatcaaagactgaaagactcctgggtagaacgcttggac
ttcaatcctgaccgctacctacaggacaacccagcgtcgggagagaagtttgcctatgtg
ccgtttggagccgggcgccatcgttgtattggagaaaattttgcctatgttcaaattaag
acaatttggtccactatgcttcgtttatatgaatttgacctcatcaatggatattttccc
agtgtgaattatacaacaatgattcataccccagaaaacccagtaatccgttacaaacga
agatcaaaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (2)   
   KEGG MODULE (3)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (1)   
   Pfam (1)   
All databases (57)   

Download RDF
DBGET integrated database retrieval system