KEGG   Rattus norvegicus (rat): 25430
Entry
25430             CDS       T01003                                 
Symbol
Dio1
Name
(RefSeq) type I iodothyronine deiodinase isoform 1
  KO
K01562  type I thyroxine 5'-deiodinase [EC:1.21.99.4]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04919  Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    25430 (Dio1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.99  With unknown physiological acceptors
    1.21.99.4  thyroxine 5'-deiodinase
     25430 (Dio1)
SSDB
Motif
Pfam: T4_deiodinase
Other DBs
NCBI-GeneID: 25430
NCBI-ProteinID: NP_067685
RGD: 2504
Ensembl: ENSRNOG00000061237
UniProt: P24389
Position
5:complement(127303089..127319784)
AA seq 257 aa
MGLSQLWLWLKRLVIFLQVALEVATGKVLMTLFPERVKQNILAMGQKTGMTRNPRFAPDN
WVPTFFSIQYFWFVLKVRWQRLEDRAEYGGLAPNCTVVRLSGQKCNVWDFIQGSRPLVLN
FGSCTUPSFLLKFDQFKRLVDDFASTADFLIIYIEEAHATDGWAFKNNVDIRQHRSLQDR
LRAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVIQEGRICYKGKPGPWNYNPEEV
RAVLEKLCIPPGHMPQF
NT seq 774 nt   +upstreamnt  +downstreamnt
atggggctgtcccagctatggctgtggctgaagcggcttgtgatattcctgcaggtagcc
ttggaggtggctacgggcaaggtgctaatgacactgttcccagagagagtcaagcagaac
atcctggccatgggccaaaagaccggaatgaccaggaatccccgattcgcccctgacaac
tgggtccccaccttcttcagcatccagtacttctggttcgtcctgaaggtccgctggcag
agactggaagacagggctgagtatggggggctggcccccaactgcaccgtggtccgcctc
tcaggacagaagtgcaacgtctgggatttcattcaaggcagcagacccctggtgttgaac
ttcggcagctgcacctgaccttcatttcttctcaaatttgaccagttcaagagactcgta
gacgactttgcctccacagctgacttcctcatcatttacattgaagaagctcacgccaca
gatggatgggcttttaagaacaacgtggacatcaggcagcaccgaagcctccaggaccgc
ctgcgggcagcacatctgctgctggccaggagcccccagtgtcctgtggtggtggacaca
atgcagaaccagagcagccagctctatgcagctctgcctgagaggctctatgtgatacag
gaaggcaggatctgctacaagggtaaacctggcccttggaactacaatcctgaggaagtc
cgagctgttctggaaaagctttgcatcccacctggacacatgcctcagttctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (1)   
   Pfam (1)   
All databases (26)   

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