KEGG   Rattus norvegicus (rat): 25489
Entry
25489             CDS       T01003                                 
Symbol
Nedd4
Name
(RefSeq) E3 ubiquitin-protein ligase NEDD4
  KO
K10591  E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04120  Ubiquitin mediated proteolysis
rno04144  Endocytosis
rno04530  Tight junction
rno05169  Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    25489 (Nedd4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    25489 (Nedd4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    25489 (Nedd4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    25489 (Nedd4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25489 (Nedd4)
   04121 Ubiquitin system [BR:rno04121]
    25489 (Nedd4)
   03029 Mitochondrial biogenesis [BR:rno03029]
    25489 (Nedd4)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     25489 (Nedd4)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    25489 (Nedd4)
Ubiquitin system [BR:rno04121]
 Ubiquitin ligases (E3)
  HECT type E3
   25489 (Nedd4)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Morphogenesis factors
    25489 (Nedd4)
SSDB
Motif
Pfam: HECT WW C2
Other DBs
NCBI-GeneID: 25489
NCBI-ProteinID: NP_037118
RGD: 3157
Ensembl: ENSRNOG00000058898
UniProt: Q62940 A0A0G2K8P3 A6KEM7
Structure
Position
8:82264751..82349642
AA seq 889 aa
MSSDMAADDTEAPVLSEDEVWEFCLDKNEEGGGSPGSDVTDTCEPPCGCWELNPSSLEEE
HVLFTADPYLELHNDDTRVVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQT
KTIKKSLNPKWNEEILFRVLPQQHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRME
RPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKNGSDDENADQAEELEPGWVVLDQPDAAT
HLQHPPEPSPLPPGWEERQDVLGRTYYVNHESRTTQWKRPSPEDDLTDDENGDIQLQAQR
AFTTRRQISEDVDGPDNHESPENWEIVREDENTMYSGQAVQSPPSGHPDVQVRLAEELDT
RLTMYGNPATSQPVTSSNHSSRGGSSQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGR
SYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTPVDSNDLGPLPPGWEERTHTDGRVFF
INHNIKKTQWEDPRMQNVAITGPAVPYSRDYKRKYEFFRRKLKKQTDIPNKFEMKLRRAN
ILEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYS
ATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITL
HDMESVDSEYYSSLRWILENDPTELDLRFIIDEELFGQTHQHELKTGGSEVVVTNKNKKE
YIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREH
TKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFT
VEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD
NT seq 2670 nt   +upstreamnt  +downstreamnt
atgagctcggacatggcagccgacgacactgaggccccagtgctttcggaggacgaggta
tgggagttctgtctggataagaatgaagagggtggtggatcccccggaagtgatgtcaca
gatacttgtgagccaccatgtggatgctgggagttaaatccgagttccctggaagaggag
cacgtgcttttcactgccgatccatatctcgagcttcacaatgatgacacgcgagttgtg
agagtgaaggttatagctggcataggtctggccaagaaagacatcttgggagccagtgat
ccttatgtaagagtgacattgtatgacccgatgagtggagtccttaccagcgtgcagacg
aaaactatcaaaaagtctttgaatccaaaatggaacgaagaaatactgttcagagtcctt
ccacaacagcaccggattcttttcgaagtgtttgatgaaaatcgtttgacaagagatgat
ttcctgggtcaagtggatgtccctctctatcctttaccgactgaaaacccaagaatggag
agaccatatacatttaaggattttgttcttcatccaagaagccacaaatcaagagttaaa
ggttatctgagattaaaaatgacttacttacctaaaaacggctcagatgatgaaaatgca
gaccaggctgaggagttagagcctggctgggttgttttggaccaaccagatgctgccacc
catttgcagcatccaccagaaccttctcccctacctccagggtgggaagagaggcaggat
gtccttggaaggacctactacgtaaaccatgagtctagaacaacacaatggaaaagacca
agccctgaggatgacctcacagatgatgagaatggtgacattcagctgcaggcgcagcga
gcatttaccaccaggcggcagatatcggaggatgtggatggccctgacaaccacgagtcc
cctgagaattgggagattgtacgagaagatgagaacaccatgtacagtggtcaggctgtt
cagtcgcctccgtcaggtcacccagacgtgcaggtccgcctcgcagaggagttagatacc
agactcaccatgtatggaaacccggccaccagccagccagtcaccagctcaaaccattcc
agcagaggaggcagctcgcaaacctgtatctttgaggaacagcctacacttcctgtgctt
ttgcctacttcatctggattgccaccaggttgggaagaaaaacaagatgacagaggacga
tcgtactatgtagaccacaactctaagacaaccacatggtccaagcccaccatgcaggat
gatccaagatcgaaaattcctgctcatctgagaggaaagacaccagtcgactccaatgac
ctgggacctttacctccaggctgggaagaaagaacgcacacagatggaagggtcttcttc
ataaatcacaatataaagaagacacagtgggaagatcctcggatgcagaatgtggccata
actggaccagcagtgccctactccagagattacaaaagaaagtatgagtttttccgaagg
aagctgaagaagcagactgacattccaaacaaatttgaaatgaaacttcgccgtgcaaac
attctggaggattcttaccggagaattatgggtgtgaagagagctgacttcctcaaggcc
cgactctggattgagtttgatggtgaaaagggccttgactatggaggagttgcccgagaa
tggttcttcctcatctcaaaggagatgtttaatccctattatggcctgtttgaatattcc
gctacggacaattacactctgcagataaatccaaactcgggcttgtgtaatgaagatcac
ctctcatacttcaagttcattggccgtgtggctgggatggcggtttatcatggcaagctg
ttggatgggtttttcatccgccccttttacaagatgatgcttcagaaactgataacactg
cacgacatggagtccgtggatagtgaatattacagttctctgcgatggattcttgaaaat
gacccgacggagctggacctgagatttatcatagatgaagagctttttggacagacacat
caacacgagctgaaaactggtggatcggaggttgtggtcaccaacaagaacaaaaaggag
tatatctaccttgtaatccagtggcgatttgtgaacagaatccagaagcaaatggctgct
tttaaagagggattttttgaactgataccacaggatctgatcaagatattcgatgaaaat
gaactagagcttctcatgtgtggtctgggagatgtggacgtgaacgactggagggaacat
acaaaatacaaaaatggatacagcttaaaccaccaggtcatccactggttctggaaggct
gttttgatgatggattcagaaaaaagaatacgcttacttcagtttgttactggcacatcc
cgtgtgcctatgaatggatttgctgaactctatggctcaaatggaccacagtccttcaca
gtggaacagtggggcacccctgataagctgcccagagcacatacctgcttcaaccgcctg
gacctgccaccctatgaatcctttgacgaactctgggataaacttcagatggcgattgag
aacacgcagggctttgatggggttgattag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   Pfam (3)   
All databases (62)   

Download RDF
DBGET integrated database retrieval system