KEGG   Rattus norvegicus (rat): 25594
Entry
25594             CDS       T01003                                 
Symbol
Ppp1cb
Name
(RefSeq) serine/threonine-protein phosphatase PP1-beta catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03015  mRNA surveillance pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04114  Oocyte meiosis
rno04218  Cellular senescence
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04390  Hippo signaling pathway
rno04510  Focal adhesion
rno04611  Platelet activation
rno04720  Long-term potentiation
rno04728  Dopaminergic synapse
rno04750  Inflammatory mediator regulation of TRP channels
rno04810  Regulation of actin cytoskeleton
rno04910  Insulin signaling pathway
rno04921  Oxytocin signaling pathway
rno04931  Insulin resistance
rno05031  Amphetamine addiction
rno05034  Alcoholism
rno05168  Herpes simplex virus 1 infection
rno05205  Proteoglycans in cancer
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    25594 (Ppp1cb)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    25594 (Ppp1cb)
   04024 cAMP signaling pathway
    25594 (Ppp1cb)
   04022 cGMP-PKG signaling pathway
    25594 (Ppp1cb)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    25594 (Ppp1cb)
   04218 Cellular senescence
    25594 (Ppp1cb)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    25594 (Ppp1cb)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    25594 (Ppp1cb)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    25594 (Ppp1cb)
  09152 Endocrine system
   04910 Insulin signaling pathway
    25594 (Ppp1cb)
   04921 Oxytocin signaling pathway
    25594 (Ppp1cb)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    25594 (Ppp1cb)
   04270 Vascular smooth muscle contraction
    25594 (Ppp1cb)
  09156 Nervous system
   04728 Dopaminergic synapse
    25594 (Ppp1cb)
   04720 Long-term potentiation
    25594 (Ppp1cb)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    25594 (Ppp1cb)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    25594 (Ppp1cb)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    25594 (Ppp1cb)
  09165 Substance dependence
   05031 Amphetamine addiction
    25594 (Ppp1cb)
   05034 Alcoholism
    25594 (Ppp1cb)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    25594 (Ppp1cb)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    25594 (Ppp1cb)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    25594 (Ppp1cb)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:rno03021]
    25594 (Ppp1cb)
   03019 Messenger RNA biogenesis [BR:rno03019]
    25594 (Ppp1cb)
   03041 Spliceosome [BR:rno03041]
    25594 (Ppp1cb)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     25594 (Ppp1cb)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     25594 (Ppp1cb)
Transcription machinery [BR:rno03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     25594 (Ppp1cb)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     25594 (Ppp1cb)
Spliceosome [BR:rno03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    25594 (Ppp1cb)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 25594
NCBI-ProteinID: NP_037197
RGD: 3376
Ensembl: ENSRNOG00000004612
UniProt: P62142 A6HA24
Position
6:complement(29681099..29712835)
AA seq 327 aa
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt   +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccgcctgctggaggtacgagga
tgtcgtccgggaaaaattgtgcagatgactgaagcagaagtccgaggactgtgtatcaag
tctcgtgaaatctttcttagccagcctattcttttggaattggaagcgccactgaagatt
tgtggagatattcatggacagtatacagacttactgagattatttgaatatggaggtttt
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatctgtttgctattggcttacaaaatcaaatacccagagaacttctttcttcta
cgaggaaaccatgagtgtgctagcatcaaccgcatttatggattctatgatgagtgcaaa
cgaagatttaatattaaattgtggaagacattcactgattgttttaattgtctgcctata
gctgctattgttgatgagaaaatcttctgctgtcatggaggactgtcaccagacctacag
tctatggaacagattcggagaattatgagacccactgacgtacctgatacaggtttgctt
tgtgatttactgtggtccgacccagataaggatgtacaaggctggggagaaaatgatcgt
ggtgtttcttttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgatttg
gacttgatttgtcgagcccatcaggtggtagaagatggatatgaattttttgctaaacga
caattggtaactttattttctgccccaaattactgcggcgagtttgacaatgctggtggt
atgatgagtgtggatgaaactttgatgtgttcattccagatattgaaaccatctgaaaag
aaagctaagtaccagtatggtgggctgaattctggacgtcctgtcactccgcctcgaaca
gctaatccaccgaagaaaaggtga

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (22)   
   KEGG PATHWAY (22)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
Protein domain (2)   
   Pfam (2)   
All databases (65)   

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