KEGG   Rattus norvegicus (rat): 25699
Entry
25699             CDS       T01003                                 
Symbol
Dbh
Name
(RefSeq) dopamine beta-hydroxylase
  KO
K00503  dopamine beta-monooxygenase [EC:1.14.17.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00350  Tyrosine metabolism
rno01100  Metabolic pathways
Module
rno_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    25699 (Dbh)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.17  With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.17.1  dopamine beta-monooxygenase
     25699 (Dbh)
SSDB
Motif
Pfam: Cu2_monoox_C Cu2_monooxygen DOMON DUF5937
Other DBs
NCBI-GeneID: 25699
NCBI-ProteinID: NP_037290
RGD: 2489
Ensembl: ENSRNOG00000006641
UniProt: Q05754
Structure
Position
3:30886313..30903313
AA seq 621 aa
MQPHLSHQPCWSLPSPSVREAASMYGTAVAIFLVILVAALQGSEPPESPFPYHIPLDPEG
TLELSWNVSYDQEIIHFQLQVQGPRAGVLFGMSDRGEMENADLVMLWTDGDRTYFADAWS
DQKGQIHLDTHQDYQLLQAQRVSNSLSLLFKRPFVTCDPKDYVIEDDTVHLVYGILEEPF
QSLEAINTSGLHTGLQQVQLLKPEVSTPAMPADVQTMDIRAPDVLIPSTETTYWCYITEL
PLHFPRHHIIMYEAIVTEGNEALVHHMEVFQCTNESEAFPMFNGPCDSKMKPDRLNYCRH
VLAAWALGAKAFYYPEEAGVPFGGSGSSRFLRLEVHYHNPRNIQGRRDSSGIRLHYTASL
RPNEAGIMELGLVYTPLMAIPPQETTFVLTGYCTDRCTQMALPKSGIRIFASQLHTHLTG
RKVITVLARDGQQREVVNRDNHYSPHFQEIRMLKNAVTVHQGDVLITSCTYNTENRTMAT
VGGFGILEEMCVNYVHYYPKTELELCKSAVDDGFLQKYFHIVNRFGNEEVCTCPQASVPQ
QFASVPWNSFNRDMLKALYNYAPISVHCNKTSAVRFPGNWNLQPLPKITSAVEEPDPRCP
IRQTRGPAGPFVVITTEADTE
NT seq 1866 nt   +upstreamnt  +downstreamnt
atgcagcctcacctcagccaccagccttgctggagcctccccagccccagcgtccgtgag
gcggcttccatgtatggcactgctgtggccatcttcctggtcatcctggtggctgcactg
cagggctcggagcctccggagagccccttcccttaccacatccccctggaccctgaaggg
actttagagctctcgtggaacgtcagctatgaccaggagatcatccacttccagctccag
gtgcaagggccgagggctggggtcctgttcggaatgtcggatcgaggtgagatggagaac
gcagacctcgtcatgctctggactgacggggacaggacctactttgcggacgcctggagt
gaccagaaagggcagatccatctggatacccatcaggactaccagctgctccaggcacag
agggtgtcaaacagcctatccctgctcttcaagaggccctttgtcacctgcgaccccaag
gattatgtcattgaggatgacactgtccatctagtgtatgggatcctggaggagccattc
cagtccctggaggccatcaacacctcaggcctacatacgggactacagcaggtgcagctt
ctgaagcctgaggtctccactccagccatgcctgcggatgtacaaaccatggatatccgg
gctcctgacgtcctcatccccagcactgagaccacatactggtgctatatcactgagcta
cccctacacttcccccgacaccacatcatcatgtatgaggccattgtcacggagggcaat
gaggccctggtgcaccacatggaggtcttccaatgtacaaatgagtctgaggccttcccc
atgttcaacggaccctgcgactccaagatgaaacctgacagactcaactactgtcgccac
gtgctggcggcatgggccctgggcgccaaggcattttactacccagaagaagccggtgtc
ccctttgggggctcaggatcctcccggtttctccgactggaagttcattaccacaatcca
cggaatatacaaggccggcgcgactcctctggcatccgtctacactacacagctagtctc
cgacccaatgaggcaggcatcatggagcttggactggtgtacacgcccttgatggccatc
ccccctcaggagaccacctttgttttgactggctactgcacagacaggtgcacccagatg
gcactgccgaaatctggaatccgcatctttgcctcacagctccacacgcacctgaccggc
aggaaggtgattactgtgctcgccagggatggccaacagagggaagtggtgaacagagac
aaccactacagcccccactttcaggagatcagaatgctgaagaatgctgtgactgtccac
cagggggatgtcctcatcacttcgtgcacatacaacacagaaaacaggacaatggccaca
gtgggggggtttggaatcttggaggagatgtgcgtcaactacgtccactactaccccaaa
acagagctggagctctgcaagagtgccgtggatgatggcttcctgcagaaatacttccac
atagtaaaccggttcggcaatgaggaggtctgcacctgccctcaggcctctgtcccccag
cagttcgcctctgtgccctggaactctttcaatcgtgatatgctcaaggctttgtataac
tatgcccctatctctgtgcactgtaacaagacctctgccgtccgcttcccgggtaactgg
aacctgcagcctctgcctaagatcacttccgcagtggaagaacccgacccacgctgcccc
atccgacagactcggggacccgccggccccttcgttgtcatcaccacggaggcagacact
gagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (33)   

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