KEGG   Rattus norvegicus (rat): 25734
Entry
25734             CDS       T01003                                 
Symbol
Hck
Name
(RefSeq) tyrosine-protein kinase HCK
  KO
K08893  hemopoietic cell kinase [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04062  Chemokine signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    25734 (Hck)
   04062 Chemokine signaling pathway
    25734 (Hck)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    25734 (Hck)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    25734 (Hck)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    25734 (Hck)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     25734 (Hck)
Protein kinases [BR:rno01001]
 Non-receptor tyrosine kinases
  SRC family
   25734 (Hck)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    25734 (Hck)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH3_3 Haspin_kinase
Other DBs
NCBI-GeneID: 25734
NCBI-ProteinID: NP_037317
RGD: 2785
Ensembl: ENSRNOG00000009331
UniProt: P50545
Position
3:162031833..162074933
AA seq 524 aa
MGGRSSCEDPGCPRGEGRVPRMGCVKSRFLREGSKASKIEPNANQKGPVYVPDPTSPKKL
GPNSINSLPPGVVEGSEDTIVVALYDYEAIHREDLSFQKGDQMVVLEESGEWWKARSLAT
KKEGYIPSNYVARVNSLETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSL
SVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVVHYKKGKDGLCQKLSVPCV
SPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAF
LAEANLMKTLQHDKLVKLHAVVSQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFS
AQISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIK
WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNC
PEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
NT seq 1575 nt   +upstreamnt  +downstreamnt
ctggggggtcgttcgagctgcgaggatccgggctgcccgcgaggcgaagggcgggtgccc
aggatgggatgtgtgaagtccaggttcctccgagaaggaagcaaggcctcaaaaatagag
ccaaatgccaaccagaaaggccctgtgtatgtgccggatcccacgtcccctaagaagctg
ggaccgaacagcatcaacagcctgcccccgggggtcgtggagggctctgaggacaccatt
gtggtcgcactgtacgactatgaggccattcaccgtgaagacctcagcttccagaaggga
gaccagatggtggttctggaggagtctggggagtggtggaaggcccgttccctggctacc
aagaaagaaggctatatcccaagcaattatgtagctcgagttaactctttggagactgag
gagtggttcttcaagggtatcagccggaaggatgcagagcgccacctgctggctcccggg
aacatgctgggctccttcatgatccgggacagtgagaccaccaaagggagctactcactt
tctgttcgagactttgacccccagcacggagacacggtgaagcattataaaatccggaca
ctggacagtggaggcttctacatctctccgaggagcaccttcagcagcctgcaggaactt
gtcgtccactacaagaaggggaaggatgggctctgccagaagctgtcagtgccctgtgtg
tctcccaaaccccagaagccatgggagaaagatgcctgggagattcctcgagaatccctc
cagatggagaagaaactgggagccgggcagtttggagaagtgtggatggccacctacaac
aagcacaccaaagtggcggtgaagacaatgaagccagggagcatgtctgtggaggccttc
ctggcagaggccaacctgatgaagacgttacagcatgataaactggtgaagctgcacgcc
gtggtctctcaggagcccatctttattgtcaccgagttcatggccaaaggaagcctgctg
gactttctcaagagtgaagaaggcagcaagcagccactgccaaaactcattgacttctca
gcccagatttcagagggcatggctttcattgagcagaggaactacatccaccgagacctc
cgggctgccaacatcttggtttctgcatcactggtgtgtaagatcgctgactttggactg
gcacggatcatcgaggacaatgagtacacagctcgggaaggagccaagttccccatcaag
tggacagctcctgaagccatcaactttggctccttcaccatcaagtcagatgtctggtcc
tttggtatcctgctgatggaaatcgtcacctacggccggatcccttacccaggtatgtca
aacccagaggtgattcgagcactagagcatgggtaccgtatgcctcgaccagataactgc
ccagaggagctctacagtatcatgatccgctgctggaagaaccgtccagaggaacggccc
actttcgaatacatccagagcgtgctggatgacttctacacggccactgagagccagtat
cagcagcaaccttga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (9)   
   Pfam (9)   
All databases (36)   

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