KEGG   Rattus norvegicus (rat): 25748
Entry
25748             CDS       T01003                                 
Symbol
Alas2
Name
(RefSeq) 5-aminolevulinate synthase, erythroid-specific, mitochondrial
  KO
K00643  5-aminolevulinate synthase [EC:2.3.1.37]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00260  Glycine, serine and threonine metabolism
rno00860  Porphyrin metabolism
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
Module
rno_M00868  Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    25748 (Alas2)
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    25748 (Alas2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:rno01007]
    25748 (Alas2)
Enzymes [BR:rno01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.37  5-aminolevulinate synthase
     25748 (Alas2)
Amino acid related enzymes [BR:rno01007]
 Aminotransferase (transaminase)
  Class II
   25748 (Alas2)
SSDB
Motif
Pfam: Aminotran_1_2 Preseq_ALAS Aminotran_5 Cys_Met_Meta_PP DegT_DnrJ_EryC1 Beta_elim_lyase
Other DBs
NCBI-GeneID: 25748
NCBI-ProteinID: NP_037329
RGD: 2084
Ensembl: ENSRNOG00000000167
UniProt: Q63147
Position
X:22890650..22914046
AA seq 587 aa
MVAAAMLLRSCPVLSKGPTGLLGKVAKTYQFLFGIGRCPILATQGPTCSQIHLKATKAGA
DSPSWTKSHCPFMLSELQDRKSKIVQRAAPEVQEDVKTFKTDLLSFMESTTRSQSVPRFQ
DPEQTGGAPPLLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQH
FSEASMDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELE
QELAELHHKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKF
VFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVH
AVGLYGTRGAGIGERDGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRV
GNAALNSKICDLLLAKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAW
TEVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
NT seq 1764 nt   +upstreamnt  +downstreamnt
atggtggcagcagctatgttgctacggtcctgtccagtgctctctaagggccccacaggc
ctcctaggcaaagtggctaaaacttaccagttcctatttggtattggacgctgccccatc
ctggccactcaaggaccaacctgttctcaaatccatcttaaggcaaccaaggctggagca
gactctccgtcttggactaagagccattgtcctttcatgctgtcagaactccaagacagg
aagagcaagattgtgcagagggcagctccagaagtccaagaggatgtcaagactttcaag
acagacctgctgagcttcatggagtcaactacccgaagccaatcagtgcctcgtttccag
gatccagagcagactggaggggcacctcccctgctgattcagaataatatgactggaagc
caggcttttggttatgaccaattttttagagacaagatcatggaaaagaagcaggaccac
acataccgtgtgttcaagactgtgaatcgctgggctaatgcctacccctttgcccaacac
ttctccgaggcatctatggactcaaaggatgtttctgtctggtgcagtaatgactatttg
ggcataagcaggcaccctcgtgtcttgcaggccatagaggagaccctgaagaatcatgga
gctggagctgggggcactcgcaatatctcaggtacaagcaagtttcatgtggagcttgaa
caggagctggctgaactacatcataaggactcggctctgctcttctcctcctgttttgtg
gccaatgattctactctctttacactggccaagcttctgccagggtgtgagatctactca
gacgcaggcaatcatgcctccatgatccaaggcattcgtaacagtggtgcagtcaagttt
gtcttcagacacaatgacccaggccacctgaagaaacttcttgagaagtccgatcccaag
acaccaaaaattgtggcttttgagactgttcactccatggatggtgccatctgtcctctg
gaggaattgtgtgatgtggcccaccagtacggggccctgaccttcgtggatgaagtccat
gccgtaggactatatggaacccggggtgcagggatcggggagcgtgatggaattatgcac
aagcttgacatcatctctggaactcttggcaaggcctttggctgtgtcggtggctatatc
gccagcactcgggacttggtggacatggtgcgctcctacgctgcaggcttcatctttacc
acttcactgcctcccatggtgctctctggagctctagagtctgtgcgtctactcaaggga
gaggagggtcaagccctgaggcgtgcacaccagcgcaacgtcaaacatatgcgccagcta
ctaatggacaggggctttcctgttatcccctgtcccagccacatcatccccataagggtg
ggtaatgcggcactcaacagcaagatctgtgatcttctgctcgccaagcacagcatctat
gtgcaggccatcaactacccaactgtgcctcgtggtgaggagctgctgcgcttggccccc
tccccccaccacagccctcagatgatggaaaactttgtggagaagttgctgctggcctgg
actgaggtggggttgcccctccaagatgtgtctgtggctgcatgcaacttctgccgtcgt
cctgtgcactttgagcttatgagcgagtgggagcgatcctactttgggaacatgggaccc
caatatgttactacctatgcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (20)   
   RefSeq(nuc) (8)   
   GenBank (6)   
   EMBL (6)   
Protein domain (6)   
   Pfam (6)   
All databases (58)   

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