KEGG   Rattus norvegicus (rat): 266732
Entry
266732            CDS       T01003                                 
Symbol
Npc1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
  KO
K12385  Niemann-Pick C1 protein
Organism
rno  Rattus norvegicus (rat)
Pathway
rno03265  Virion - Ebolavirus and Lyssavirus
rno04142  Lysosome
rno04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:rno00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus and Lyssavirus
    266732 (Npc1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    266732 (Npc1)
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    266732 (Npc1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    266732 (Npc1)
Transporters [BR:rno02000]
 Solute carrier family (SLC)
  SLC65: NPC-type cholesterol transporter
   266732 (Npc1)
SSDB
Motif
Pfam: Patched NPC1_N Sterol-sensing MMPL ACR_tran
Other DBs
NCBI-GeneID: 266732
NCBI-ProteinID: NP_705888
RGD: 628693
Ensembl: ENSRNOG00000012016
Vega: OTTRNOG00000002300
UniProt: G3V7K5 A6KNH0
Position
18:complement(3654237..3699853)
AA seq 1278 aa
MGAHHPALGLLLLLLLCPAQVFSQSCVWYGECGVAFGDKRYNCEYSGPPKPLPKDGYDLV
QELCPGLFFGNVSLCCDVQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQ
FLNVTATEDYFDPETRENKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGR
DARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSVLGMEPMRNATKGCNESVDEVTGPCS
CQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLAVWCHRRRYFV
SEYTPIDSNIAFSSNSSDKGEASCCDPLGVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLV
FIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHI
YEPYPSGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNC
TIMSVLNYFQNSHAVLDNQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGG
PVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAWAWEKEFINFVKNYKNPNL
TISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIA
GILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEET
LDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCF
VSFLGLDIKRQEKNRLDILCCVRGPDDGQESQASESYLFRFFKNAFAPFLLTDWLRPVVM
AVFVGILSFSIAVVNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGYNY
SSRRGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRL
YNVTHQFCNASVIDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAY
SSAVNIMGDDTYIGATYFMTYHTILKTSADYIDALKKARLIASNITETMRSKGSDYRVFP
YSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFG
VMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFS
GITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKR
HTTQERYKGTERERLLNF
NT seq 3837 nt   +upstreamnt  +downstreamnt
atgggcgcgcaccacccggccctcggcctcctgctgctgctgctgctgtgccctgcgcag
gtgttctcacagtcctgtgtctggtacggagagtgtggagtcgcctttggagataagagg
tacaactgtgaatattcgggcccaccgaaacccctcccaaaggacggctatgacttagtg
caggaactctgtccaggactcttctttggcaatgtcagtctttgctgtgacgttcagcag
cttcagacactgaagagcaacctgcagctgcccctgcagtttctgtccaggtgtccgtca
tgtttttataacctgatgaccctgttttgtgagctaacatgtagcccgcaccagagtcag
tttctgaatgtgacagcaactgaagattatttcgaccccgagactcgggaaaataaaaca
aatgtaaaggaattagagtactacgtcggacggagctttgcgaatgcaatgtacaatgcc
tgccgagatgtggaggcgccttccagtaatgagaaggccttaggactcctgtgcggaagg
gatgcccgtgcctgcaatgccaccaactggattgagtacatgttcaacaaagacaacggg
caagcaccgtttaccatcatccccgtattttcagatctttcggttcttggaatggaaccc
atgaggaatgccaccaaaggctgcaacgagtctgtagatgaggtcacagggccgtgtagc
tgccaggactgctctgccgtctgcggccccaaaccccagcccccaccgccccctgtgccc
tggaggatcttaggtttggacgccatgtatgtcatcatgtgggtcgcctacatggcgttc
ctggtcctgttctttggaggactgctggcagtgtggtgccacagaaggcggtactttgtg
tccgagtacacccccattgacagcaacattgccttttcctcgaatagcagtgacaaaggg
gaagcctcgtgctgcgacccacttggtgtagcgtttgatgactgtctgaggcgcatgttc
acaaagtggggggctttctgtgtccggaatcccacctgcatcattttcttctcgttggtc
ttcattgctgcgtgctcttctggcctggtgtttgtccaggtcaccaccaatcccgtggag
ctctggtcagcccctcacagtcaggcccgcttggaaaaggagtactttgacaagcacttt
gggcctttctttcgtacggagcagcttattatccaggcccccaactccagcgtccatatc
tacgagccgtacccttccggagccgatgtgcccttcgggcctccattgaacaaagagatt
ctgcaccaggttctggacttacagatcgccattgaaagtatcactgcgtcctataacaat
gaaaccgtgacacttcaggacatctgtgtggcccccctctctccatacaacaagaactgc
accattatgagtgtgttaaattacttccagaacagccatgcggtgctggacaaccaagta
ggcgatgacttctttgtctatgccgattaccacacgcactttctgtactgtgtgagggct
cccgcctccttgaatgatacgagtttgctccacggcccttgcctgggcacatttggagga
cctgtgttcccgtggcttgtgttgggcggctatgatgatcagaactacaataatgccacc
gcgcttgtgattaccttccctgtcaataattactataatgacacagagaagctccagagg
gcctgggcctgggagaaagaatttattaactttgtgaagaactacaagaatccaaatctg
accatttctttcactgctgagcgaagcattgaagatgaactcaatcgggaaagcaacagt
gacgtattcaccgtcctcatcagctatgccgtgatgtttctgtacatttccctcgccctg
gggcacatccagagctggaacagggtcctggtggattctaaaatctcgctgggcattgcg
gggatcctgatagtgctgagctcggtgacctgctccctgggcatcttcagctacatcgga
atgccactgaccctcatcgtcattgaggtcatcccgttcctggtgctggctgttggggtg
gacaacatcttcattctagtgcagacctaccagagagatgagcgtcttcaggaggagacg
ttggatcagcagctgggcaggatcctgggggaagtggccccaaccatgttcctttcgtcc
ttctctgagacctcggcatttttctttggggcgctgtcctcgatgccagctgtccacacc
ttctctctgtttgcggggatggccgtcctcattgacttcctccttcagattacctgcttt
gtgagcttcttggggttagatattaagagacaagagaaaaaccgtctggacatcctgtgc
tgtgtcagaggccctgacgacggacaagaatcccaagcctccgaaagctacctgttccgc
ttcttcaaaaacgcctttgccccatttctgctgacggactggctgcggccagttgtgatg
gccgtgtttgtgggcattctgtcattcagtattgcagtagtgaacaaagtagaaatcgga
ttggatcagtctctctcgatgccaaatgattcgtatgtgattgactatttcaagtcactc
ggtcagtacctgcactcgggcccacccgtgtacttcgtcctggaagagggctacaactac
agttcccgcagagggcagaacatggtgtgcggtggcatgggctgtgacaatgactccctg
gtgcagcagatatttaacgcagcagagctggacacctacacccgcgtaggcttcgctccc
tcatcctggattgatgattactttgactgggtctcaccgcaatcctcctgctgtagactc
tacaatgtcactcaccagttctgcaatgcttctgtgattgacccaacctgtgtccgctgc
agacctctgactccagagggcaaacagaggcctcaggggaaagaattcatgaaattcctg
cccatgttcctgtctgataaccccaaccccaagtgtggcaaagggggacatgctgcttac
agttctgctgttaacatcatgggagatgacacttacattggggccacttacttcatgacc
taccacaccattcttaagacctctgctgattatatcgatgccctgaagaaagctcggctt
atagccagtaacatcacggaaaccatgcgttctaaggggagtgattatcgtgtgtttcct
tacagtgtgttctatgtcttctatgaacaatacctgaccattattgatgacgccatcttt
aacctaagtgtgtctctgggctccatatttctcgtgaccttggtggctctgggctgtgaa
ctgtggtctgcggtcatcatgtgtctcaccatagctatgatcctggtcaacatgtttggt
gttatgtggctgtggggcatcagtctgaacgctgtttccttggtcaacttggtgatgacc
tgtggcatttctgtggagttctgcagccatataacaagagctttcaccatgagcaccaaa
ggaagcagagtgagcagggcggaagaggcactggcccacatgggtagttctgtattcagt
ggaatcacacttacaaaatttggagggatcgtggtgttggcctttgccaagtctcaaatt
tttgagatcttttacttcaggatgtacttagccatggtcttacttggagctactcacgga
ctaatatttcttcccgtcttactcagttacatagggccatcagtgaataaagctaaaaga
cacaccactcaagagcggtacaaagggacagagagagaacggctcctcaatttttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (30)   

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